Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development T Ueda, R Watanabe-Fukunaga, H Fukuyama, S Nagata, R Fukunaga Molecular and cellular biology 24 (15), 6539-6549, 2004 | 615 | 2004 |
Dissecting eIF4E action in tumorigenesis HG Wendel, RLA Silva, A Malina, JR Mills, H Zhu, T Ueda, ... Genes & development 21 (24), 3232-3237, 2007 | 575 | 2007 |
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ... Genes & development 26 (18), 2038-2049, 2012 | 352 | 2012 |
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development T Ueda, M Sasaki, AJ Elia, IIC Chio, K Hamada, R Fukunaga, TW Mak Proceedings of the National Academy of Sciences 107 (32), 13984-13990, 2010 | 234 | 2010 |
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2 S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ... Cancer cell 30 (2), 337-348, 2016 | 217 | 2016 |
Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation X Wang, P Yue, CB Chan, K Ye, T Ueda, R Watanabe-Fukunaga, ... Molecular and cellular biology 27 (21), 7405-7413, 2007 | 197 | 2007 |
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ... Genes & development 27 (10), 1101-1114, 2013 | 152 | 2013 |
Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cells D Walsh, C Arias, C Perez, D Halladin, M Escandon, T Ueda, ... Molecular and cellular biology 28 (8), 2648-2658, 2008 | 127 | 2008 |
Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E Y Li, P Yue, X Deng, T Ueda, R Fukunaga, FR Khuri, SY Sun Neoplasia 12 (10), 848-855, 2010 | 104 | 2010 |
Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction K Kobatake, K Ikeda, Y Nakata, N Yamasaki, T Ueda, A Kanai, K Sentani, ... Clinical Cancer Research 26 (8), 2065-2079, 2020 | 99 | 2020 |
Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses S Joshi, S Kaur, AJ Redig, K Goldsborough, K David, T Ueda, ... Proceedings of the National Academy of Sciences 106 (29), 12097-12102, 2009 | 95 | 2009 |
Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model T Berger, T Ueda, E Arpaia, IIC Chio, EA Shirdel, I Jurisica, K Hamada, ... Oncogene 32 (41), 4989-4994, 2013 | 71 | 2013 |
Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2 T Ueda, A Nagamachi, K Takubo, N Yamasaki, H Matsui, A Kanai, ... Blood, The Journal of the American Society of Hematology 125 (22), 3437-3446, 2015 | 67 | 2015 |
EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms T Ueda, M Sanada, H Matsui, N Yamasaki, ZI Honda, LY Shih, H Mori, ... Leukemia 26 (12), 2557-2560, 2012 | 65 | 2012 |
Loss of MNK function sensitizes fibroblasts to serum‐withdrawal induced apoptosis CA Chrestensen, A Eschenroeder, WG Ross, T Ueda, ... Genes to cells 12 (10), 1133-1140, 2007 | 51 | 2007 |
CIZ1, a p21Cip1/Waf1‐interacting protein, functions as a tumor suppressor in vivo R Nishibe, W Watanabe, T Ueda, N Yamasaki, R Koller, L Wolff, Z Honda, ... FEBS letters 587 (10), 1529-1535, 2013 | 50 | 2013 |
Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2 B Dolniak, E Katsoulidis, N Carayol, JK Altman, AJ Redig, MS Tallman, ... Journal of biological chemistry 283 (18), 12034-12042, 2008 | 49 | 2008 |
TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation IIC Chio, M Sasaki, D Ghazarian, J Moreno, S Done, T Ueda, S Inoue, ... Nature cell biology 14 (6), 625-633, 2012 | 44 | 2012 |
Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling M Chevillard-Briet, M Quaranta, A Grézy, L Mattera, C Courilleau, ... Human molecular genetics 23 (8), 2120-2131, 2014 | 41 | 2014 |
Negative regulatory effects of Mnk kinases in the generation of chemotherapy-induced antileukemic responses JK Altman, H Glaser, A Sassano, S Joshi, T Ueda, R Watanabe-Fukunaga, ... Molecular pharmacology 78 (4), 778-784, 2010 | 39 | 2010 |