| Improved low molecular weight Myc-Max inhibitors H Wang, DI Hammoudeh, AV Follis, BE Reese, JS Lazo, SJ Metallo, ... Molecular cancer therapeutics 6 (9), 2399-2408, 2007 | 252 | 2007 |
| Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules AV Follis, DI Hammoudeh, H Wang, EV Prochownik, SJ Metallo Chemistry & biology 15 (11), 1149-1155, 2008 | 204 | 2008 |
| c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle H Wang, S Mannava, V Grachtchouk, D Zhuang, MS Soengas, ... Oncogene 27 (13), 1905-1915, 2008 | 190 | 2008 |
| Asparagine synthetase gene TaASN1 from wheat is up-regulated by salt stress, osmotic stress and ABA H Wang, D Liu, J Sun, A Zhang Journal of Plant Physiology 162 (1), 81-89, 2005 | 119 | 2005 |
| Perturbation of the c-Myc–Max protein–protein interaction via synthetic α-helix mimetics KY Jung, H Wang, P Teriete, JL Yap, L Chen, ME Lanning, A Hu, ... Journal of medicinal chemistry 58 (7), 3002-3024, 2015 | 111 | 2015 |
| Discovery of novel Myc− Max heterodimer disruptors with a three-dimensional pharmacophore model G Mustata, AV Follis, DI Hammoudeh, SJ Metallo, H Wang, ... Journal of medicinal chemistry 52 (5), 1247-1250, 2009 | 101 | 2009 |
| Pharmacophore identification of c-Myc inhibitor 10074-G5 JL Yap, H Wang, A Hu, J Chauhan, KY Jung, RB Gharavi, EV Prochownik, ... Bioorganic & medicinal chemistry letters 23 (1), 370-374, 2013 | 87 | 2013 |
| The metabolic fates of pyruvate in normal and neoplastic cells EV Prochownik, H Wang Cells 10 (4), 762, 2021 | 71 | 2021 |
| Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5 H Wang, J Chauhan, A Hu, K Pendleton, JL Yap, PE Sabato, JW Jones, ... Oncotarget 4 (6), 936, 2013 | 70 | 2013 |
| Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids H Wang, P Teriete, A Hu, D Raveendra-Panickar, K Pendelton, JS Lazo, ... Oncotarget 6 (32), 32380, 2015 | 59 | 2015 |
| Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma*♦ H Wang, J Lu, LR Edmunds, S Kulkarni, J Dolezal, J Tao, S Ranganathan, ... Journal of Biological Chemistry 291 (51), 26241-26251, 2016 | 52 | 2016 |
| Discovery of Methyl 4′‐Methyl‐5‐(7‐nitrobenzo[c][1,2,5]oxadiazol‐4‐yl)‐[1,1′‐biphenyl]‐3‐carboxylate, an Improved Small‐Molecule Inhibitor of c‐Myc–Max … J Chauhan, H Wang, JL Yap, PE Sabato, A Hu, EV Prochownik, ... ChemMedChem 9 (10), 2274-2285, 2014 | 50 | 2014 |
| Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma JM Dolezal, H Wang, S Kulkarni, L Jackson, J Lu, S Ranganathan, ... Journal of Biological Chemistry 292 (24), 10068-10086, 2017 | 49 | 2017 |
| Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice H Wang, JM Dolezal, S Kulkarni, J Lu, J Mandel, LE Jackson, ... Journal of Biological Chemistry 293 (38), 14740-14757, 2018 | 44 | 2018 |
| β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice W Zhang, J Meyfeldt, H Wang, S Kulkarni, J Lu, JA Mandel, B Marburger, ... Journal of Biological Chemistry 294 (46), 17524-17542, 2019 | 42 | 2019 |
| Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion H Wang, L Sharma, J Lu, P Finch, S Fletcher, EV Prochownik Oncotarget 6 (18), 15857, 2015 | 41 | 2015 |
| c-Myc and AMPK control cellular energy levels by cooperatively regulating mitochondrial structure and function LR Edmunds, L Sharma, H Wang, A Kang, S d’Souza, J Lu, M McLaughlin, ... PloS one 10 (7), e0134049, 2015 | 36 | 2015 |
| The pyridoxal kinase gene TaPdxK from wheat complements vitamin B6 synthesis-defective Escherichia coli H Wang, D Liu, C Liu, A Zhang Journal of plant physiology 161 (9), 1053-1060, 2004 | 32 | 2004 |
| Distribution and virulence diversity of Phytophthora sojae in China Z Zhendong, W Huabo, W Xiaoming, C Ruzhen, W Xiaofei Agricultural Sciences in China 3 (2), 116-123, 2004 | 32 | 2004 |
| Ribosomopathy-like properties of murine and human cancers S Kulkarni, JM Dolezal, H Wang, L Jackson, J Lu, BP Frodey, ... PloS one 12 (8), e0182705, 2017 | 31 | 2017 |
Edward V. ProchownikProfessor University of Pittsburgh School of Medicine and CHP of UPMC在 chp.edu 的电子邮件经过验证
Edward V. ProchownikProfessor University of Pittsburgh School of Medicine and CHP of UPMC在 chp.edu 的电子邮件经过验证