1,3,7-Triethyl-substituted xanthines—possess nanomolar affinity for the adenosine A1 receptor MM Van der Walt, G Terre’Blanche Bioorganic & medicinal chemistry 23 (20), 6641-6649, 2015 | 39 | 2015 |
2-Aminopyrimidines as dual adenosine A1/A2A antagonists SJ Robinson, JP Petzer, G Terre’Blanche, A Petzer, MM Van der Walt, ... European journal of medicinal chemistry 104, 177-188, 2015 | 33 | 2015 |
The adenosine A2A antagonistic properties of selected C8-substituted xanthines MM Van der Walt, G Terre’Blanche, A Petzer, ACU Lourens, JP Petzer Bioorganic chemistry 49, 49-58, 2013 | 33 | 2013 |
Evaluation of 2‐benzylidene‐1‐tetralone derivatives as antagonists of A1 and A2A adenosine receptors LJ Legoabe, MM Van der Walt, G Terre'Blanche Chemical biology & drug design 91 (1), 234-244, 2018 | 22 | 2018 |
5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions HDJ van Rensburg, G Terre'Blanche, MM van der Walt, LJ Legoabe Bioorganic Chemistry 74, 251-259, 2017 | 22 | 2017 |
5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions. RHD Janse, G Terre'Blanche, MM Van der Walt, LJ Legoabe Bioorganic chemistry 74, 251, 2017 | 22 | 2017 |
The adenosine receptor affinities and monoamine oxidase B inhibitory properties of sulfanylphthalimide analogues MM Van der Walt, G Terre’Blanche, A Petzer, JP Petzer Bioorganic chemistry 59, 117-123, 2015 | 20 | 2015 |
Imidazo [1, 2-α] pyridines possess adenosine A1 receptor affinity for the potential treatment of cognition in neurological disorders R Lefin, MM Van der Walt, PJ Milne, G Terre'Blanche Bioorganic & medicinal chemistry letters 27 (17), 3963-3967, 2017 | 18 | 2017 |
Selected C8 two-chain linkers enhance the adenosine A1/A2A receptor affinity and selectivity of caffeine MM Van der Walt, G Terre'Blanche European journal of medicinal chemistry 125, 652-656, 2017 | 17 | 2017 |
2–Benzylidene–1–Indanone Analogues as Dual Adenosine A1/A2a Receptor Antagonists for the Potential Treatment of Neurological Conditions HDJ van Rensburg, LJ Legoabe, G Terre’Blanche, MM Van der Walt Drug research, 2019 | 16 | 2019 |
Methoxy substituted 2-benzylidene-1-indanone derivatives as A 1 and/or A 2A AR antagonists for the potential treatment of neurological conditions HDJ van Rensburg, LJ Legoabe, G Terre'Blanche, MM Van der Walt MedChemComm 10 (2), 300-309, 2019 | 15 | 2019 |
Benzyloxynitrostyrene analogues–A novel class of selective and highly potent inhibitors of monoamine oxidase B MM Van der Walt, G Terre’Blanche, JP Petzer, A Petzer European journal of medicinal chemistry 125, 1193-1199, 2017 | 15 | 2017 |
Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A1 and A2A receptor antagonists R Harmse, MM Van der Walt, JP Petzer, G Terre’Blanche Bioorganic & medicinal chemistry letters 26 (24), 5951-5955, 2016 | 12 | 2016 |
In Silico Drug Discovery Strategies Identified ADMET Properties of Decoquinate RMB041 and Its Potential Drug Targets against Mycobacterium tuberculosis KE Knoll, MM van der Walt, DT Loots Microbiology Spectrum 10 (2), e02315-21, 2022 | 11 | 2022 |
Benzopyrone represents a privilege scaffold to identify novel adenosine A1/A2A receptor antagonists MM Van der Walt, G Terre'Blanche Bioorganic chemistry 77, 136-143, 2018 | 11 | 2018 |
Treatment of an adrenomyeloneuropathy patient with Lorenzo's oil and supplementation with docosahexaenoic acid-A case report G Terre'Blanche, MM Van der Walt, JJ Bergh, LJ Mienie Lipids in health and disease 10 (1), 152, 2011 | 10 | 2011 |
C2-substituted quinazolinone derivatives exhibit A1 and/or A2A adenosine receptor affinities in the low micromolar range L Pieterse, MM Van der Walt, G Terre'Blanche Bioorganic & Medicinal Chemistry Letters 30 (16), 127274, 2020 | 9 | 2020 |
Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B MM Van der Walt, G Terre’Blanche, ACU Lourens, A Petzer, JP Petzer Bioorganic & medicinal chemistry letters 22 (24), 7367-7370, 2012 | 9 | 2012 |
Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B MM Van der Walt, G Terre’Blanche, A Petzer, JP Petzer Bioorganic & medicinal chemistry letters 22 (21), 6632-6635, 2012 | 8 | 2012 |
8-(3-phenylpropyl)-1, 3, 7-triethylxanthine is a synthetic caffeine substitute with stronger metabolic modulator activity DF Carrageta, TR Dias, I Jarak, MG Alves, PF Oliveira, MM Van der Walt, ... Toxicology in Vitro 53, 114-120, 2018 | 3 | 2018 |