TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins, JK Perry, ... G3: Genes, Genomes, Genetics 9 (8), 2775-2786, 2019 | 13 | 2019 |
IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways M Alhilali, JI Hearn, J Rong, L Jain, SM Bolam, AP Monk, JT Munro, ... Cellular signalling 87, 110143, 2021 | 11 | 2021 |
Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease development RC Poulsen, L Jain, N Dalbeth Arthritis Research & Therapy 25 (1), 59, 2023 | 10 | 2023 |
Monosodium urate crystals alter the circadian clock in macrophages leading to loss of NLRP3 inflammasome repression: Implications for timing of the gout flare D Popov, L Jain, M Alhilali, N Dalbeth, RC Poulsen The FASEB Journal 37 (6), e22940, 2023 | 9 | 2023 |
Differential expression of steroid hormone receptors and ten eleven translocation proteins in endometrial cancer cells V Mahajan, P Gujral, L Jain, AP Ponnampalam Frontiers in Oncology 12, 763464, 2022 | 8 | 2022 |
Differential effects of hypoxia versus hyperoxia or physoxia on phenotype and energy metabolism in human chondrocytes from osteoarthritic compared to macroscopically normal … L Jain, SM Bolam, AP Monk, JT Munro, E Chen, J Tamatea, N Dalbeth, ... International Journal of Molecular Sciences 24 (8), 7532, 2023 | 5 | 2023 |
3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry Journal of Molecular Endocrinology 64 (4), 209-222, 2020 | 5 | 2020 |
Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development? L Jain, CA Jardim, R Yulo, SM Bolam, AP Monk, JT Munro, R Pitto, ... Osteoarthritis and Cartilage 32 (9), 1084-1096, 2024 | 4 | 2024 |
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes JGB Primrose, L Jain, SM Bolam, AP Monk, JT Munro, N Dalbeth, ... Connective Tissue Research 64 (5), 457-468, 2023 | 2 | 2023 |
REST, RCOR1 and RCOR2 expression is reduced in osteoarthritic chondrocytes and contributes to increasing MMP13 and ADAMTS5 expression through upregulating HES1 JGB Primrose, L Jain, M Alhilali, SM Bolam, AP Monk, JT Munro, ... Cellular Signalling 109, 110800, 2023 | 2 | 2023 |
Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions L Jain, SM Bolam, P Monk, JT Munro, J Tamatea, N Dalbeth, RC Poulsen Journal of Cellular Physiology, 2024 | 1 | 2024 |
Characterisation of growth hormone signal transduction in primary melanoma cell lines KS Sousa, K Tran, S Kolekar, L Jain, Y Wang, PR Shepherd, J Perry Annals of Oncology 30, v9, 2019 | 1 | 2019 |
OR01-04 The Growth Hormone Receptor Interacts With Transcriptional Regulator, HMGN1, Upon GH-induced Nuclear Translocation L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ... Journal of the Endocrine Society 7 (Supplement_1), bvad114. 1086, 2023 | | 2023 |
The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ... Journal of Cell Communication and Signaling 17 (3), 925-937, 2023 | | 2023 |
SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry Journal of the Endocrine Society 4 (Supplement_1), SAT-303, 2020 | | 2020 |
A genomic, proteomic and transcriptomic investigation into growth hormone actions L Jain PhD Thesis-University of Auckland, 2020 | | 2020 |
TNF-α Differentially Regulates Cell Cycle Genes In Promyelocytic TNF-Differentially Regulates Cell Cycle Genes In Promyelocytic And Granulocytic HL-60/S4 Cells EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins | | |