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Lekha Jain
Lekha Jain
Research Fellow, University of Auckland
在 auckland.ac.nz 的电子邮件经过验证
标题
引用次数
引用次数
年份
TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells
EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins, JK Perry, ...
G3: Genes, Genomes, Genetics 9 (8), 2775-2786, 2019
132019
IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways
M Alhilali, JI Hearn, J Rong, L Jain, SM Bolam, AP Monk, JT Munro, ...
Cellular signalling 87, 110143, 2021
112021
Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease development
RC Poulsen, L Jain, N Dalbeth
Arthritis Research & Therapy 25 (1), 59, 2023
102023
Monosodium urate crystals alter the circadian clock in macrophages leading to loss of NLRP3 inflammasome repression: Implications for timing of the gout flare
D Popov, L Jain, M Alhilali, N Dalbeth, RC Poulsen
The FASEB Journal 37 (6), e22940, 2023
92023
Differential expression of steroid hormone receptors and ten eleven translocation proteins in endometrial cancer cells
V Mahajan, P Gujral, L Jain, AP Ponnampalam
Frontiers in Oncology 12, 763464, 2022
82022
Differential effects of hypoxia versus hyperoxia or physoxia on phenotype and energy metabolism in human chondrocytes from osteoarthritic compared to macroscopically normal …
L Jain, SM Bolam, AP Monk, JT Munro, E Chen, J Tamatea, N Dalbeth, ...
International Journal of Molecular Sciences 24 (8), 7532, 2023
52023
3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways
L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry
Journal of Molecular Endocrinology 64 (4), 209-222, 2020
52020
Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development?
L Jain, CA Jardim, R Yulo, SM Bolam, AP Monk, JT Munro, R Pitto, ...
Osteoarthritis and Cartilage 32 (9), 1084-1096, 2024
42024
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes
JGB Primrose, L Jain, SM Bolam, AP Monk, JT Munro, N Dalbeth, ...
Connective Tissue Research 64 (5), 457-468, 2023
22023
REST, RCOR1 and RCOR2 expression is reduced in osteoarthritic chondrocytes and contributes to increasing MMP13 and ADAMTS5 expression through upregulating HES1
JGB Primrose, L Jain, M Alhilali, SM Bolam, AP Monk, JT Munro, ...
Cellular Signalling 109, 110800, 2023
22023
Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions
L Jain, SM Bolam, P Monk, JT Munro, J Tamatea, N Dalbeth, RC Poulsen
Journal of Cellular Physiology, 2024
12024
Characterisation of growth hormone signal transduction in primary melanoma cell lines
KS Sousa, K Tran, S Kolekar, L Jain, Y Wang, PR Shepherd, J Perry
Annals of Oncology 30, v9, 2019
12019
OR01-04 The Growth Hormone Receptor Interacts With Transcriptional Regulator, HMGN1, Upon GH-induced Nuclear Translocation
L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ...
Journal of the Endocrine Society 7 (Supplement_1), bvad114. 1086, 2023
2023
The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation
L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ...
Journal of Cell Communication and Signaling 17 (3), 925-937, 2023
2023
SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways
L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry
Journal of the Endocrine Society 4 (Supplement_1), SAT-303, 2020
2020
A genomic, proteomic and transcriptomic investigation into growth hormone actions
L Jain
PhD Thesis-University of Auckland, 2020
2020
TNF-α Differentially Regulates Cell Cycle Genes In Promyelocytic TNF-Differentially Regulates Cell Cycle Genes In Promyelocytic And Granulocytic HL-60/S4 Cells
EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins
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