Using graph theory to analyze biological networks GA Pavlopoulos, M Secrier, CN Moschopoulos, TG Soldatos, S Kossida, ... BioData mining 4, 1-27, 2011 | 883 | 2011 |
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ... Nature genetics 46 (8), 837-843, 2014 | 384 | 2014 |
Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance M Secrier, X Li, N De Silva, MD Eldridge, G Contino, J Bornschein, ... Nature genetics 48 (10), 1131-1141, 2016 | 366 | 2016 |
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics X Li, HE Francies, M Secrier, J Perner, A Miremadi, N Galeano-Dalmau, ... Nature communications 9 (1), 2983, 2018 | 302 | 2018 |
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 603 (7899), 131-137, 2022 | 238 | 2022 |
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia M Prudencio, J Humphrey, S Pickles, AL Brown, SE Hill, JM Kachergus, ... The Journal of clinical investigation 130 (11), 2020 | 140 | 2020 |
Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma F Noble, MA Lloyd, R Turkington, E Griffiths, M O'Donovan, JR O'Neill, ... Journal of British Surgery 104 (13), 1816-1828, 2017 | 104 | 2017 |
Identification of prognostic phenotypes of esophageal adenocarcinoma in 2 independent cohorts T Sawas, S Killcoyne, PG Iyer, KK Wang, TC Smyrk, JB Kisiel, Y Qin, ... Gastroenterology 155 (6), 1720-1728. e4, 2018 | 86 | 2018 |
Identification of subtypes of Barrett’s esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome data SG Jammula, AC Katz-Summercorn, X Li, C Linossi, E Smyth, S Killcoyne, ... Gastroenterology 158 (6), 1682-1697. e1, 2020 | 80 | 2020 |
Molecular landscape of esophageal cancer: implications for early detection and personalized therapy FR Talukdar, M di Pietro, M Secrier, M Moehler, K Goepfert, SSC Lima, ... Annals of the New York Academy of Sciences 1434 (1), 342-359, 2018 | 80 | 2018 |
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma A Noorani, X Li, M Goddard, J Crawte, LB Alexandrov, M Secrier, ... Nature genetics 52 (1), 74-83, 2020 | 65 | 2020 |
Visualizing time-related data in biology, a review M Secrier, R Schneider Briefings in bioinformatics 15 (5), 771-782, 2014 | 60 | 2014 |
Arena3D: visualizing time-driven phenotypic differences in biological systems M Secrier, GA Pavlopoulos, J Aerts, R Schneider BMC bioinformatics 13, 1-11, 2012 | 59 | 2012 |
The ABC of reverse engineering biological signalling systems M Secrier, T Toni, MPH Stumpf Molecular BioSystems 5 (12), 1925-1935, 2009 | 58 | 2009 |
Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, ... Science translational medicine 16 (734), eadg7162, 2024 | 47 | 2024 |
Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium. Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with … M Secrier, X Li, N de Silva, MD Eldridge, G Contino, J Bornschein, ... Nat Genet 48 (10), 1131-1141, 2016 | 36 | 2016 |
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease U Šušnjar, N Škrabar, AL Brown, Y Abbassi, H Phatnani, A Cortese, ... Communications biology 5 (1), 314, 2022 | 35 | 2022 |
Molecular effects of Lapatinib in the treatment of HER2 overexpressing oesophago-gastric adenocarcinoma N De Silva, L Schulz, A Paterson, W Qain, M Secrier, E Godfrey, H Cheow, ... British journal of cancer 113 (9), 1305-1312, 2015 | 31 | 2015 |
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 E Garcia, A Hayden, C Birts, E Britton, A Cowie, K Pickard, M Mellone, ... Scientific reports 6 (1), 32417, 2016 | 30 | 2016 |
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre-and post-chemotherapy A Noorani, J Bornschein, AG Lynch, M Secrier, A Achilleos, M Eldridge, ... Genome research 27 (6), 902-912, 2017 | 28 | 2017 |