Screening of candidate regulators for cellulase and hemicellulase production in Trichoderma reesei and identification of a factor essential for cellulase production M Häkkinen, MJ Valkonen, A Westerholm-Parvinen, N Aro, M Arvas, ... Biotechnology for biofuels 7, 1-21, 2014 | 248 | 2014 |
A novel two‐component regulatory system in Bacillus subtilis for the survival of severe secretion stress HL Hyyryläinen, A Bolhuis, E Darmon, L Muukkonen, P Koski, ... Molecular microbiology 41 (5), 1159-1172, 2001 | 206 | 2001 |
Transformation System for Hypocrea jecorina (Trichoderma reesei) That Favors Homologous Integration and Employs Reusable Bidirectionally Selectable Markers MG Steiger, M Vitikainen, P Uskonen, K Brunner, G Adam, T Pakula, ... Applied and environmental microbiology 77 (1), 114-121, 2011 | 159 | 2011 |
D-Alanine substitution of teichoic acids as a modulator of protein folding and stability at the cytoplasmic membrane/cell wall interface of Bacillus subtilis HL Hyyryläinen, M Vitikainen, J Thwaite, H Wu, M Sarvas, CR Harwood, ... Journal of Biological Chemistry 275 (35), 26696-26703, 2000 | 158 | 2000 |
Structure-function analysis of PrsA reveals roles for the parvulin-like and flanking N-and C-terminal domains in protein folding and secretion in Bacillus subtilis M Vitikainen, I Lappalainen, R Seppala, H Antelmann, H Boer, S Taira, ... Journal of Biological Chemistry 279 (18), 19302-19314, 2004 | 130 | 2004 |
Quantitation of the Capacity of the Secretion Apparatus and Requirement for PrsA in Growth and Secretion of α-Amylase inBacillus subtilis M Vitikainen, T Pummi, U Airaksinen, E Wahlström, H Wu, M Sarvas, ... Journal of bacteriology 183 (6), 1881-1890, 2001 | 117 | 2001 |
Array comparative genomic hybridization analysis of Trichoderma reesei strains with enhanced cellulase production properties M Vitikainen, M Arvas, T Pakula, M Oja, M Penttilä, M Saloheimo BMC genomics 11, 1-16, 2010 | 99 | 2010 |
Penicillin‐binding protein folding is dependent on the PrsA peptidyl‐prolyl cis‐trans isomerase in Bacillus subtilis HL Hyyryläinen, BC Marciniak, K Dahncke, M Pietiäinen, P Courtin, ... Molecular microbiology 77 (1), 108-127, 2010 | 84 | 2010 |
Secretion of heterologous proteins in Bacillus subtilis can be improved by engineering cell components affecting post‐translocational protein folding and degradation M Vitikainen, HL Hyyryläinen, A Kivimäki, VP Kontinen, M Sarvas Journal of Applied Microbiology 99 (2), 363-375, 2005 | 78 | 2005 |
Novel genetic tools that enable highly pure protein production in Trichoderma reesei A Rantasalo, M Vitikainen, T Paasikallio, J Jäntti, CP Landowski, ... Scientific reports 9 (1), 5032, 2019 | 74 | 2019 |
The extracytoplasmic folding factor PrsA is required for protein secretion only in the presence of the cell wall in Bacillus subtilis E Wahlstrom, M Vitikainen, VP Kontinen, M Sarvas Microbiology 149 (3), 569-577, 2003 | 65 | 2003 |
Elastic and pH-responsive hybrid interfaces created with engineered resilin and nanocellulose W Fang, A Paananen, M Vitikainen, S Koskela, A Westerholm-Parvinen, ... Biomacromolecules 18 (6), 1866-1873, 2017 | 32 | 2017 |
Development of a modular vaccine platform for multimeric antigen display using an orthobunyavirus model A Aebischer, K Wernike, P König, K Franzke, PJ Wichgers Schreur, ... Vaccines 9 (6), 651, 2021 | 22 | 2021 |
Coacervation of resilin fusion proteins containing terminal functionalities W Fang, M Vitikainen, P Mohammadi, S Koskela, M Soikkeli, ... Colloids and Surfaces B: Biointerfaces 171, 590-596, 2018 | 16 | 2018 |
In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 … LA Espinosa, Y Ramos, I Andújar, EO Torres, G Cabrera, A Martín, ... Analytical and Bioanalytical Chemistry 413 (30), 7559-7585, 2021 | 15 | 2021 |
A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice L Lazo, M Bequet-Romero, G Lemos, A Musacchio, A Cabrales, AJ Bruno, ... Vaccine 40 (8), 1162-1169, 2022 | 13 | 2022 |
Toxicity and Local Tolerance of a Novel Spike Protein RBD Vaccine Against SARS-CoV-2, Produced Using the C1 Thermothelomyces Heterothallica Protein … Y Ramot, N Kronfeld, Y Ophir, N Ezov, S Friedman, M Saloheimo, ... Toxicologic Pathology 50 (3), 294-307, 2022 | 10 | 2022 |
Detecting novel genes with sparse arrays M Arvas, N Haiminen, B Smit, J Rautio, M Vitikainen, M Wiebe, D Martinez, ... Gene 467 (1-2), 41-51, 2010 | 9 | 2010 |
Thermophilic Filamentous Fungus C1-Cell-Cloned SARS-CoV-2-Spike-RBD-Subunit-Vaccine Adjuvanted with Aldydrogel®85 Protects K18-hACE2 Mice against … R Nechooshtan, S Ehrlich, M Vitikainen, A Makovitzki, E Dor, H Marcus, ... Vaccines 10 (12), 2119, 2022 | 5 | 2022 |
Method for improved protein production in filamentous fungi T PAKULA, M SALOHEIMO, M HÄKKINEN, ... EP Patent 2,733,210, 2014 | 4 | 2014 |