The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds F Fontana, M Raimondi, M Marzagalli, A Di Domizio, P Limonta Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1873 (2), 188338, 2020 | 119 | 2020 |
3D proteome-wide scale screening and activity evaluation of a new ALKBH5 inhibitor in U87 glioblastoma cell line A Malacrida, M Rivara, A Di Domizio, G Cislaghi, M Miloso, V Zuliani, ... Bioorganic & Medicinal Chemistry 28 (4), 115300, 2020 | 109 | 2020 |
Natural compounds in prostate cancer prevention and treatment: mechanisms of action and molecular targets F Fontana, M Raimondi, M Marzagalli, A Di Domizio, P Limonta Cells 9 (2), 460, 2020 | 72 | 2020 |
First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand A Palmioli, E Sacco, S Abraham, CJ Thomas, A Di Domizio, L De Gioia, ... Bioorganic & medicinal chemistry letters 19 (15), 4217-4222, 2009 | 55 | 2009 |
Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RasG13D A Palmioli, E Sacco, C Airoldi, F Di Nicolantonio, A D’Urzo, S Shirasawa, ... Biochemical and Biophysical Research Communications 386 (4), 593-597, 2009 | 46 | 2009 |
Unraveling the molecular mechanisms and the potential chemopreventive/therapeutic properties of natural compounds in melanoma F Fontana, M Raimondi, A Di Domizio, RM Moretti, MM Marelli, P Limonta Seminars in Cancer Biology 59, 266-282, 2019 | 27 | 2019 |
Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target S Giatti, A Di Domizio, S Diviccaro, E Falvo, D Caruso, A Contini, R Melcangi J. Med. Chem., 2021 | 22 | 2021 |
MV1035 overcomes temozolomide resistance in patient-derived glioblastoma stem cell lines A Malacrida, A Di Domizio, A Bentivegna, G Cislaghi, E Messuti, ... Biology 11 (1), 70, 2022 | 14 | 2022 |
AMPK and diseases: state of the art regulation by AMPK-targeting molecules O Tarasiuk, M Miceli, A Di Domizio, G Nicolini Biology 11 (7), 1041, 2022 | 13 | 2022 |
SPILLO-PBSS: Detecting hidden binding sites within protein 3D-structures through a flexible structure-based approach A Di Domizio*, A Vitriolo, G Vistoli, A Pedretti J. Comput. Chem. (Software News and Updates) 35 (27), 2005–2017, 2014 | 13 | 2014 |
Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect A Malacrida, S Semperboni, A Di Domizio, A Palmioli, L Broggi, C Airoldi, ... Scientific Reports 11 (1), 10523, 2021 | 8 | 2021 |
Identification of a novel off-target of paroxetine: Possible role in sexual dysfunction induced by this SSRI antidepressant drug S Giatti, A Di Domizio, S Diviccaro, L Cioffi, I Marmorini, E Falvo, D Caruso, ... Journal of Molecular Structure 1268, 133690, 2022 | 4 | 2022 |
Sugar-Based Inhibitors of Ras Activation: Biological Activity and Identification of Ras–Inhibitor Binding Interface A Di Domizio, F Peri The Enzymes 33, 95-116, 2013 | 2 | 2013 |
Natural compounds in prostate cancer prevention and treatment: Mechanisms of action and molecular targets. Cells. 2020, 9, 460 F Fontana, M Raimondi, M Marzagalli, A Di Domizio, P Limonta | 2 | |
Differential pattern of neurotoxicity induced by the gliadin peptides p31-43 and p57-68 in in vitro model of epilepsy E Gerace, F Resta, L Curti, A Di Domizio, G Ranieri, M Becatti, D Renzi, ... Biochemical Pharmacology, 116409, 2024 | | 2024 |
Fraisinib: a calixpyrrole derivative reducing A549 cells-derived NSCLC tumor in-vivo, acts as ligand of the Glycine-tRNA Synthase, a new molecular target in oncology I Ben Toumia, T Bachetti, L Chekir-Ghedira, A Profumo, M Ponassi, ... Frontiers in Pharmacology 14, 1258108, 2024 | | 2024 |
Potential in-vitro antiviral activity of MV1035 on SARS-CoV-2 wild type viruses L Benincasa, E Molesti, A Manenti, E Montomoli, A Malacrida, V Zuliani, ... Letters in Drug Design & Discovery 20 (10), 1656-1663, 2023 | | 2023 |
Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology TI Ben, T Bachetti, L Chekir-Ghedira, A Profumo, M Ponassi, A Di Domizio, ... Frontiers in Pharmacology (Web) 14, 1258108, 2023 | | 2023 |
Innovative 3D proteome-wide scale identification of ALKBH5 target for MV1035 small molecule able to reduce migration and invasiveness in U87 glioblastoma cell lines by SPILLO-PBSS A Malacrida, M Rivara, OB Mariem, A Di Domizio, G Cislaghi, M Miloso, ... Biomedical Science and Engineering 5 (s1), 2021 | | 2021 |
Deciphering the ligand/xenobiotic molecular recognition mechanism in SLC transporters via a new structural binding site analysis O Ben Mariem, A Di Domizio, L Palazzolo, I Eberini | | 2021 |