Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target. HT Gilbert, N Hodson, P Baird, SM Richardson, JA Hoyland Scientific Reports 6, 37360, 2016 | 133 | 2016 |
Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion NM Blythe, K Muraki, MJ Ludlow, V Stylianidis, HTJ Gilbert, EL Evans, ... Journal of Biological Chemistry 294 (46), 17395-17408, 2019 | 121 | 2019 |
In situ-forming robust chitosan-poly (ethylene glycol) hydrogels prepared by copper-free azide–alkyne click reaction for tissue engineering VX Truong, MP Ablett, HTJ Gilbert, J Bowen, SM Richardson, JA Hoyland, ... Biomaterials Science 2 (2), 167-175, 2014 | 106 | 2014 |
The response of human anulus fibrosus cells to cyclic tensile strain is frequency‐dependent and altered with disc degeneration HTJ Gilbert, JA Hoyland, SJ Millward‐Sadler Arthritis & Rheumatism 62 (11), 3385-3394, 2010 | 92 | 2010 |
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading HTJ Gilbert, V Mallikarjun, O Dobre, MR Jackson, R Pedley, AP Gilmore, ... Nature communications 10 (1), 4149, 2019 | 62 | 2019 |
The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with … HTJ Gilbert, JA Hoyland, AJ Freemont, SJ Millward-Sadler Arthritis research & therapy 13, 1-12, 2011 | 53 | 2011 |
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness A Galarza Torre, JE Shaw, A Wood, HTJ Gilbert, O Dobre, P Genever, ... Scientific reports 8 (1), 8981, 2018 | 45 | 2018 |
Integrin–dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degeneration HTJ Gilbert, NS Nagra, AJ Freemont, SJ Millward-Sadler, JA Hoyland PLoS One 8 (9), e72994, 2013 | 45* | 2013 |
Fabrication of 3-dimensional cellular constructs via microstereolithography using a simple, three-component, poly (ethylene glycol) acrylate-based system SJ Leigh, HTJ Gilbert, IA Barker, JM Becker, SM Richardson, JA Hoyland, ... Biomacromolecules 14 (1), 186-192, 2013 | 39 | 2013 |
A microstereolithography resin based on thiol-ene chemistry: towards biocompatible 3D extracellular constructs for tissue engineering SMRAPD Ian A. Barker a, Matthew P. Ablett b, Hamish T. J. Gilbert b, Simon J ... Biomaterials Science 2 (4), 472-475, 2014 | 38 | 2014 |
Stem cell regeneration of degenerated intervertebral discs: current status (update) HTJ Gilbert, JA Hoyland, SM Richardson Current pain and headache reports 17, 1-9, 2013 | 36 | 2013 |
The consequences of ageing, progeroid syndromes and cellular senescence on mechanotransduction and the nucleus HTJ Gilbert, J Swift Experimental cell research 378 (1), 98-103, 2019 | 19 | 2019 |
Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells NW Hodson, S Patel, SM Richardson, JA Hoyland, HTJ Gilbert JOR spine 1 (1), e1004, 2018 | 18 | 2018 |
Regenerative response of degenerate human nucleus pulposus cells to GDF6 stimulation T Hodgkinson, HTJ Gilbert, T Pandya, AD Diwan, JA Hoyland, ... International Journal of Molecular Sciences 21 (19), 7143, 2020 | 11 | 2020 |
Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human mesenchymal stem cells J Llewellyn, V Mallikarjun, E Appleton, M Osipova, HTJ Gilbert, ... Proceedings of the National Academy of Sciences 120 (14), e2210745120, 2023 | 5 | 2023 |
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading HTJ Gilbert, V Mallikarjun, O Dobre, MR Jackson, R Pedley, AP Gilmore, ... bioRxiv, 317404, 2018 | 5 | 2018 |
Stimulation of cardiac fibroblast Piezo1 channels opposes myofibroblast differentiation and induces IL-6 secretion via Ca2+-mediated p38 MAP kinase activation NM Blythe, V Stylianidis, MJ Ludlow, HTJ Gilbert, EL Evans, ... BioRxiv, 603456, 2019 | 4 | 2019 |
Interior decoration: Adapting multiwell plates for high throughput mechanobiology HTJ Gilbert, J Swift Biotechnology Journal 10 (10), 1513-1514, 2015 | 4 | 2015 |
Senescence inhibits the chaperone response to thermal stress J Llewellyn, V Mallikarjun, E Appleton, M Osipova, HTJ Gilbert, ... bioRxiv, 2021.06. 15.448532, 2021 | 3 | 2021 |
Molecular Pathways of Mechanotransduction: From Extracellular Matrix to Nucleus HTJ Gilbert, J Swift Mechanobiology: Exploitation for Medical Benefit, 23-42, 2017 | 3 | 2017 |