Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008 | 3471 | 2008 |
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011 | 1032 | 2011 |
Unravelling the structural and mechanistic basis of CRISPR–Cas systems J Van Der Oost, ER Westra, RN Jackson, B Wiedenheft Nature Reviews Microbiology 12 (7), 479-492, 2014 | 858 | 2014 |
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 741 | 2012 |
CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009 | 722 | 2009 |
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011 | 707 | 2011 |
DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014 | 470 | 2014 |
Prophages mediate defense against phage infection through diverse mechanisms J Bondy-Denomy, J Qian, ER Westra, A Buckling, DS Guttman, ... The ISME journal 10 (12), 2854-2866, 2016 | 432 | 2016 |
The CRISPRs, They Are A-Changin': How Prokaryotes Generate Adaptive Immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual Reviews of Genetics 46 (1), 311, 2012 | 404 | 2012 |
CRISPR–Cas systems: beyond adaptive immunity ER Westra, A Buckling, PC Fineran Nature Reviews Microbiology 12 (5), 317-326, 2014 | 375 | 2014 |
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010 | 316 | 2010 |
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014 | 307 | 2014 |
Interactions between bacterial and phage communities in natural environments A Chevallereau, BJ Pons, S van Houte, ER Westra Nature Reviews Microbiology 20 (1), 49-62, 2022 | 294 | 2022 |
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), e1003742, 2013 | 278 | 2013 |
Parasite exposure drives selective evolution of constitutive versus inducible defense ER Westra, S van Houte, S Oyesiku-Blakemore, B Makin, JM Broniewski, ... Current biology 25 (8), 1043-1049, 2015 | 274 | 2015 |
The diversity-generating benefits of a prokaryotic adaptive immune system S van Houte, AKE Ekroth, JM Broniewski, H Chabas, B Ashby, ... Nature 532 (7599), 385-388, 2016 | 266 | 2016 |
Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system NM Høyland-Kroghsbo, J Paczkowski, S Mukherjee, J Broniewski, ... Proceedings of the National Academy of Sciences 114 (1), 131-135, 2017 | 263 | 2017 |
Evolutionary ecology of prokaryotic immune mechanisms S van Houte, A Buckling, ER Westra Microbiology and Molecular Biology Reviews 80 (3), 745-763, 2016 | 253 | 2016 |
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes S Al-Attar, ER Westra, J Van Der Oost, SJJ Brouns Walter de Gruyter 392 (4), 277-289, 2011 | 233 | 2011 |
Anti-CRISPR phages cooperate to overcome CRISPR-Cas immunity M Landsberger, S Gandon, S Meaden, C Rollie, A Chevallereau, ... Cell 174 (4), 908-916. e12, 2018 | 213 | 2018 |