Palladium-triggered deprotection chemistry for protein activation in living cells J Li, J Yu, J Zhao, J Wang, S Zheng, S Lin, L Chen, M Yang, S Jia, ... Nature chemistry 6 (4), 352-361, 2014 | 426 | 2014 |
Optimized tetrazine derivatives for rapid bioorthogonal decaging in living cells X Fan, Y Ge, F Lin, Y Yang, G Zhang, WSC Ngai, Z Lin, S Zheng, J Wang, ... Angewandte Chemie 128 (45), 14252-14256, 2016 | 178 | 2016 |
Time-resolved protein activation by proximal decaging in living systems J Wang, Y Liu, Y Liu, S Zheng, X Wang, J Zhao, F Yang, G Zhang, ... Nature 569 (7757), 509-513, 2019 | 167 | 2019 |
Enzyme-Mediated Intercellular Proximity Labeling for Detecting Cell–Cell Interactions Y Ge, L Chen, S Liu, J Zhao, H Zhang, PR Chen Journal of the American Chemical Society 141 (5), 1833-1837, 2019 | 97 | 2019 |
A genetically encoded FRET sensor for intracellular heme Y Song, M Yang, SV Wegner, J Zhao, R Zhu, Y Wu, C He, PR Chen ACS chemical biology 10 (7), 1610-1615, 2015 | 91 | 2015 |
Genetically encoded photoaffinity histone marks X Xie, XM Li, F Qin, J Lin, G Zhang, J Zhao, X Bao, R Zhu, H Song, XD Li, ... Journal of the American Chemical Society 139 (19), 6522-6525, 2017 | 64 | 2017 |
Mechanism-based design of a photoactivatable firefly luciferase J Zhao, S Lin, Y Huang, J Zhao, PR Chen Journal of the American Chemical Society 135 (20), 7410-7413, 2013 | 61 | 2013 |
Water-soluble triscyclometalated organoiridium complex: phosphorescent nanoparticle formation, nonlinear optics, and application for cell imaging Y Fan, J Zhao, Q Yan, PR Chen, D Zhao ACS applied materials & interfaces 6 (5), 3122-3131, 2014 | 43 | 2014 |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction R Zhu, G Zhang, M Jing, Y Han, J Li, J Zhao, Y Li, PR Chen Nature Communications 12 (1), 581, 2021 | 40 | 2021 |
Cationic Lipid‐based Intracellular Delivery of Bacterial Effectors for Rewiring Malignant Cell Signaling S Yang, Q Tang, L Chen, J Chang, T Jiang, J Zhao, M Wang, PR Chen Angewandte Chemie International Edition 59 (41), 18087-18094, 2020 | 27 | 2020 |
Structural characterization of the DNA-binding mechanism underlying the copper (II)-sensing MarR transcriptional regulator R Zhu, Z Hao, H Lou, Y Song, J Zhao, Y Chen, J Zhu, PR Chen JBIC Journal of Biological Inorganic Chemistry 22, 685-693, 2017 | 27 | 2017 |
Naturally occurring hotspot cancer mutations in Gα13 promote oncogenic signaling M Maziarz, A Federico, J Zhao, L Dujmusic, Z Zhao, S Monti, X Varelas, ... Journal of Biological Chemistry 295 (49), 16897-16904, 2020 | 23 | 2020 |
Bioorthogonal Engineering of Bacterial Effectors for Spatial–Temporal Modulation of Cell Signaling J Zhao, Y Liu, F Lin, W Wang, S Yang, Y Ge, PR Chen ACS Central Science 5 (1), 145-152, 2018 | 19 | 2018 |
Direct interrogation of context-dependent GPCR activity with a universal biosensor platform R Janicot, M Maziarz, JC Park, J Zhao, A Luebbers, E Green, CE Philibert, ... Cell 187 (6), 1527-1546. e25, 2024 | 15 | 2024 |
DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi A Marivin, M Maziarz, J Zhao, V DiGiacomo, IO Calvo, EA Mann, J Ear, ... Journal of Biological Chemistry 295 (8), 2270-2284, 2020 | 14 | 2020 |
Dissection of kinase isoforms through orthogonal and chemical inducible signaling cascades S Zheng, X Fan, J Wang, J Zhao, PR Chen ChemBioChem 18 (16), 1593-1598, 2017 | 11 | 2017 |
Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer J Zhao, V DiGiacomo, M Ferreras-Gutierrez, S Dastjerdi, ... Proceedings of the National Academy of Sciences 120 (18), e2213140120, 2023 | 9 | 2023 |
Structural and mechanistic study of the cysteine oxidation-mediated induction of the Escherichia coli MarR regulator R Zhu, Z Hao, H Lou, Y Song, J Zhao, J Zhu, PR Chen Tetrahedron 73 (26), 3714-3719, 2017 | 6 | 2017 |
Direct detection of endogenous Gαi activity in cells with a sensitive conformational biosensor A Luebbers, R Janicot, J Zhao, CE Philibert, M Garcia-Marcos bioRxiv, 2024.08. 21.609006, 2024 | | 2024 |
Identification of Peptide Sequence Served as Genetically-Encoded or Chemical Probes to Inhibit Gαs in Cells J Zhao, A Luebbers, M Maziarz, M Garcia-Marcos Journal of Biological Chemistry 299 (3), 104348, 2023 | | 2023 |