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Thomas Wood
Thomas Wood
Sr. Scientist HTS, Enamine
在 enamine.net 的电子邮件经过验证
标题
引用次数
引用次数
年份
Semisynthetic lipopeptides derived from nisin display antibacterial activity and lipid II binding on par with that of the parent compound
T Koopmans, TM Wood, P ’t Hart, LHJ Kleijn, APA Hendrickx, RJL Willems, ...
Journal of the american chemical society 137 (29), 9382-9389, 2015
772015
The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry
TM Wood, NI Martin
MedChemComm 10 (5), 634-646, 2019
562019
Quantification of protein glycosylation using nanopores
RCA Versloot, FLR Lucas, L Yakovlieva, MJ Tadema, Y Zhang, TM Wood, ...
Nano Letters 22 (13), 5357-5364, 2022
342022
Binding studies reveal phospholipid specificity and its role in the calcium-dependent mechanism of action of daptomycin
I Kotsogianni, TM Wood, FM Alexander, SA Cochrane, NI Martin
ACS Infectious Diseases 7 (9), 2612-2619, 2021
302021
A High‐Resolution Crystal Structure that Reveals Molecular Details of Target Recognition by the Calcium‐Dependent Lipopeptide Antibiotic Laspartomycin C
LHJ Kleijn, HC Vlieg, TM Wood, J Sastre Toraño, BJC Janssen, NI Martin
Angewandte Chemie International Edition 56 (52), 16546-16549, 2017
302017
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase
A Cioce, G Bineva-Todd, AJ Agbay, J Choi, TM Wood, MF Debets, ...
ACS chemical biology 16 (10), 1961-1967, 2021
282021
Cell-specific bioorthogonal tagging of glycoproteins
A Cioce, B Calle, T Rizou, SC Lowery, VL Bridgeman, KE Mahoney, ...
Nature Communications 13 (1), 6237, 2022
232022
P.’t Hart, LHJ Kleijn, APA Hendrickx, RJL Willems, E. Breukink and NI Martin
T Koopmans, TM Wood
J. Am. Chem. Soc 137, 9382-9389, 2015
182015
De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria
TM Wood, KHME Tehrani, RM van Harten, M Śleszyńska, IR Rebollo, ...
Chemical science 8 (12), 7991-7997, 2017
172017
Mechanistic insights into the C 55-P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures
TM Wood, MR Zeronian, N Buijs, K Bertheussen, HK Abedian, ...
Chemical Science 13 (10), 2985-2991, 2022
112022
The contribution of achiral residues in the laspartomycin family of calcium-dependent lipopeptide antibiotics
TM Wood, K Bertheussen, NI Martin
Organic & Biomolecular Chemistry 18 (3), 514-517, 2020
102020
A convenient chemoenzymatic preparation of chimeric macrocyclic peptide antibiotics with potent activity against gram-negative pathogens
TM Wood, CJ Slingerland, NI Martin
Journal of Medicinal Chemistry 64 (15), 10890-10899, 2021
92021
Thrombin-derived peptides potentiate the activity of Gram-positive-specific antibiotics against Gram-negative bacteria
CMJ Wesseling, TM Wood, CJ Slingerland, K Bertheussen, S Lok, ...
Molecules 26 (7), 1954, 2021
92021
The Cell Envelope Stress Response of Bacillus subtilis towards Laspartomycin C
A Diehl, TM Wood, S Gebhard, NI Martin, G Fritz
Antibiotics 9 (11), 729, 2020
82020
The plant stress hormone jasmonic acid evokes defensive responses in streptomycetes
A Van der Meij, SS Elsayed, C Du, J Willemse, TM Wood, NI Martin, ...
Applied and Environmental Microbiology 89 (11), e01239-23, 2023
62023
Chimeric peptidomimetic antibiotic efficiently neutralizes lipopolysaccharides (LPS) and bacteria-induced activation of RAW macrophages
A Javed, CJ Slingerland, TM Wood, NI Martin, F Broere, MH Weingarth, ...
ACS Infectious Diseases 9 (3), 518-526, 2023
52023
A β-hairpin epitope as novel structural requirement for protein arginine rhamnosylation
L Yakovlieva, TM Wood, J Kemmink, I Kotsogianni, F Koller, J Lassak, ...
Chemical Science 12 (4), 1560-1567, 2021
52021
Metabolic Engineering Optimizes Bioorthogonal Glycan Labeling in Living Cells
A Cioce, G Bineva-Todd, AJ Agbay, J Choi, TM Wood, M Debets, ...
22021
Synthetic and Mechanistic Studies with Biologically Active Macrocyclic Peptides
TM Wood
Utrecht University, 2021
2021
Structure-activity studies and high-resolution crystal structures provide new mechanistic insights into C
TM Wood, MR Zeronian, HK Abedian, AV Johnson, NM Pearce, M Lutz, ...
Structural studies on cell surface receptors and lipopeptide antibiotics, 93, 2021
2021
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