Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease EL Konrath, CS Passos, LC Klein-Júnior, AT Henriques Journal of Pharmacy and Pharmacology 65 (12), 1701-1725, 2013 | 267 | 2013 |
Characterization of Lignanamides from Hemp (Cannabis sativa L.) Seed and Their Antioxidant and Acetylcholinesterase Inhibitory Activities X Yan, J Tang, C dos Santos Passos, A Nurisso, CA Simões-Pires, M Ji, ... Journal of agricultural and food chemistry 63 (49), 10611-10619, 2015 | 183 | 2015 |
Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors CS Passos, CA Simões-Pires, A Nurisso, TC Soldi, L Kato, ... Phytochemistry 86, 8-20, 2013 | 111 | 2013 |
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases R Farina, L Pisani, M Catto, O Nicolotti, D Gadaleta, N Denora, ... Journal of medicinal chemistry 58 (14), 5561-5578, 2015 | 104 | 2015 |
Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts EL Konrath, BM Neves, PS Lunardi, C dos Santos Passos, ... Journal of Ethnopharmacology 139 (1), 58-67, 2012 | 96 | 2012 |
Terpenóides com atividade sobre o Sistema Nervoso Central (SNC) CS Passos, MD Arbo, SMK Rates, GL Poser Revista Brasileira de Farmacognosia 19, 140-149, 2009 | 71 | 2009 |
Psychollatine, a Glucosidic Monoterpene Indole Alkaloid from Psychotria umbellata VA Kerber, CS Passos, H Verli, AG Fett-Neto, JP Quirion, AT Henriques Journal of natural products 71 (4), 697-700, 2008 | 57 | 2008 |
Monoamine oxidase inhibition by monoterpene indole alkaloids and fractions obtained from Psychotria suterella and Psychotria laciniata C dos Santos Passos, TC Soldi, R Torres Abib, M Anders Apel, ... Journal of Enzyme Inhibition and Medicinal Chemistry 28 (3), 611-618, 2013 | 54 | 2013 |
Indole alkaloids and semisynthetic indole derivatives as multifunctional scaffolds aiming the inhibition of enzymes related to neurodegenerative diseases–a focus on Psychotria … L Carlos Klein-Junior, C dos Santos Passos, A Pereira Moraes, ... Current Topics in Medicinal Chemistry 14 (8), 1056-1075, 2014 | 50 | 2014 |
A rational approach for the identification of non-hydroxamate HDAC6-selective inhibitors L Goracci, N Deschamps, GM Randazzo, C Petit, C Dos Santos Passos, ... Scientific reports 6 (1), 29086, 2016 | 46 | 2016 |
Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis LC Klein-Júnior, S Cretton, PM Allard, G Genta-Jouve, CS Passos, ... Journal of natural products 80 (11), 3032-3037, 2017 | 40 | 2017 |
Combining in vitro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration JM de Mello Andrade, C dos Santos Passos, MAK Rubio, JN Mendonça, ... Chemico-biological interactions 254, 135-145, 2016 | 35 | 2016 |
Strictosidinic acid, isolated from Psychotria myriantha Mull. Arg.(Rubiaceae), decreases serotonin levels in rat hippocampus FM Farias, CS Passos, MD Arbo, DM Barros, C Gottfried, VM Steffen, ... Fitoterapia 83 (6), 1138-1143, 2012 | 32 | 2012 |
Huperzia quadrifariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain EL Konrath, BM Neves, CS Passos, PS Lunardi, MG Ortega, JL Cabrera, ... Phytomedicine 19 (14), 1321-1324, 2012 | 26 | 2012 |
5-Benzylidene-hydantoin is a new scaffold for Sirt inhibition: From virtual screening to activity assays L Sacconnay, L Ryckewaert, GM Randazzo, C Petit, CDS Passos, ... European Journal of Pharmaceutical Sciences 85, 59-67, 2016 | 24 | 2016 |
Alkaloids as inhibitors of monoamine oxidases and their role in the central nervous system CDS Passos, C Simoes-Pires, A Henriques, M Cuendet, PA Carrupt, ... Studies in Natural Products Chemistry 43, 123-144, 2014 | 24 | 2014 |
Beyond Organoleptic Characteristics: The Pharmacological Potential of Flavonoids and their Role in Leukocyte Migration and in L‐Selectin and β2‐Integrin … ES Suyenaga, LC Klein‐Júnior, CS Passos, R Marin, JR Santin, ... Phytotherapy Research 28 (9), 1406-1411, 2014 | 21 | 2014 |
The catechol-O-methyltransferase inhibitory potential of Z-vallesiachotamine by in silico and in vitro approaches CS Passos, LC Klein-Júnior, JMM Andrade, C Matté, AT Henriques Revista Brasileira de Farmacognosia 25, 382-386, 2015 | 20 | 2015 |
Monoamine levels in rat striatum after acute intraperitoneal injection of strictosidinic acid isolated from Psychotria myriantha Mull. Arg.(Rubiaceae) FM Farias, CS Passos, MD Arbo, JAS Zuanazzi, VM Steffen, ... Phytomedicine 17 (3-4), 289-291, 2010 | 20 | 2010 |
Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair M Wang, W Li, N Tomimatsu, HY Corey, JH Ji, S Alejo, SR Witus, ... Molecular cell 83 (20), 3679-3691. e8, 2023 | 17 | 2023 |