α/β-Peptide foldamers targeting intracellular protein–protein interactions with activity in living cells JW Checco, EF Lee, M Evangelista, NJ Sleebs, K Rogers, ... Journal of the American Chemical Society 137 (35), 11365-11375, 2015 | 137 | 2015 |
Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold JW Checco, DF Kreitler, NC Thomas, DG Belair, NJ Rettko, WL Murphy, ... Proceedings of the National Academy of Sciences 112 (15), 4552-4557, 2015 | 111 | 2015 |
Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling HS Haase, KJ Peterson-Kaufman, SK Lan Levengood, JW Checco, ... Journal of the American Chemical Society 134 (18), 7652-7655, 2012 | 102 | 2012 |
Targeting recognition surfaces on natural proteins with peptidic foldamers JW Checco, SH Gellman Current opinion in structural biology 39, 96-105, 2016 | 91 | 2016 |
Structure‐guided rational design of α/β‐peptide foldamers with high affinity for BCL‐2 family prosurvival proteins BJ Smith, EF Lee, JW Checco, M Evangelista, SH Gellman, WD Fairlie ChemBioChem 14 (13), 1564-1572, 2013 | 74 | 2013 |
Aplysia allatotropin-related peptide and its newly identified d-amino acid–containing epimer both activate a receptor and a neuronal target JW Checco, G Zhang, W Yuan, Z Le, J Jing, JV Sweedler Journal of Biological Chemistry 293 (43), 16862-16873, 2018 | 33 | 2018 |
Molecular and Physiological Characterization of a Receptor for d-Amino Acid-Containing Neuropeptides JW Checco, G Zhang, W Yuan, K Yu, S Yin, RH Roberts-Galbraith, ... ACS chemical biology 13 (5), 1343-1352, 2018 | 33 | 2018 |
Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF JW Checco, SH Gellman ChemBioChem 18 (3), 291-299, 2017 | 25 | 2017 |
Advancing d-amino acid-containing peptide discovery in the metazoan DH Mast, JW Checco, JV Sweedler Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1869 (1), 140553, 2021 | 23 | 2021 |
Differential Post-Translational Amino Acid Isomerization Found among Neuropeptides in Aplysia californica DH Mast, JW Checco, JV Sweedler ACS chemical biology 15 (1), 272-281, 2019 | 23 | 2019 |
Identifying receptors for neuropeptides and peptide hormones: challenges and recent progress MSR Abid, S Mousavi, JW Checco ACS chemical biology 16 (2), 251-263, 2021 | 22 | 2021 |
Conformational investigation of the structure–activity relationship of GdFFD and its analogues on an achatin-like neuropeptide receptor of Aplysia californica involved in the … TD Do, JW Checco, M Tro, JE Shea, MT Bowers, JV Sweedler Physical Chemistry Chemical Physics 20 (34), 22047-22057, 2018 | 13 | 2018 |
Mass spectrometry approaches empowering neuropeptide discovery and therapeutics KDB Anapindi, EV Romanova, JW Checco, JV Sweedler Pharmacological Reviews 74 (3), 662-679, 2022 | 9 | 2022 |
Non-targeted Identification of d-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS HC Tai, JW Checco, JV Sweedler Peptidomics: Methods and Strategies, 107-118, 2018 | 9 | 2018 |
AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction SQ Guo, YD Li, P Chen, G Zhang, HY Wang, HM Jiang, WJ Liu, JP Xu, ... Journal of Biological Chemistry 298 (10), 2022 | 8 | 2022 |
Short-term administration of common anesthetics does not dramatically change the endogenous peptide profile in the rat pituitary S Mousavi, H Qiu, FI Heinis, MSR Abid, MT Andrews, JW Checco ACS chemical neuroscience 13 (19), 2888-2896, 2022 | 8 | 2022 |
Endogenous l- to d-amino acid residue isomerization modulates selectivity between distinct neuropeptide receptor family members BM Yussif, CV Blasing, JW Checco Proceedings of the National Academy of Sciences 120 (11), e2217604120, 2023 | 7 | 2023 |
Trimer-to-monomer disruption mechanism for a potent, protease-resistant antagonist of tumor necrosis factor-α signaling J Niu, AJ Cederstrand, GA Eddinger, B Yin, JW Checco, CA Bingman, ... Journal of the American Chemical Society 144 (22), 9610-9617, 2022 | 7 | 2022 |
Peptidomics analysis reveals changes in small urinary peptides in patients with interstitial cystitis/bladder pain syndrome MSR Abid, H Qiu, BA Tripp, A de Lima Leite, HE Roth, J Adamec, ... Scientific reports 12 (1), 8289, 2022 | 7 | 2022 |
Peptidomic analysis reveals seasonal neuropeptide and peptide hormone changes in the hypothalamus and pituitary of a hibernating mammal S Mousavi, H Qiu, MT Andrews, JW Checco ACS Chemical Neuroscience 14 (14), 2569-2581, 2023 | 6 | 2023 |