| Atherton–Todd reaction: mechanism, scope and applications SS Le Corre, M Berchel, H Couthon-Gourvès, JP Haelters, PA Jaffrès Beilstein journal of organic chemistry 10 (1), 1166-1196, 2014 | 189 | 2014 |
| Phosphonic acid: preparation and applications CM Sevrain, M Berchel, H Couthon, PA Jaffrès Beilstein journal of organic chemistry 13 (1), 2186-2213, 2017 | 164 | 2017 |
| Synthesis of gem-bisphosphonic methotrexate conjugates and their biological response towards Walker's osteosarcoma G Sturtz, H Couthon, O Fabulet, M Mian, S Rosini European journal of medicinal chemistry 28 (11), 899-903, 1993 | 75 | 1993 |
| Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy PA Jaffres, C Gajate, AM Bouchet, H Couthon-Gourves, A Chantôme, ... Pharmacology & Therapeutics 165, 114-131, 2016 | 71 | 2016 |
| New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis A Girault, JP Haelters, M Potier-Cartereau, A Chantôme, M Pinault, ... Current cancer drug targets 11 (9), 1111-1125, 2011 | 68 | 2011 |
| Targeted delivery of antineoplastic agent to bone: biodistribution studies of technetium-99m-labeled gem-bisphosphonate conjugate of methotrexate. F Hosain, RP Spencer, HM Couthon, GL Sturtz Journal of Nuclear Medicine: Official Publication, Society of Nuclear …, 1996 | 68 | 1996 |
| Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery M Berchel, T Le Gall, H Couthon-Gourvès, JP Haelters, T Montier, ... Biochimie 94 (1), 33-41, 2012 | 55 | 2012 |
| The gene transfection properties of a lipophosphoramidate derivative with two phytanyl chains MF Lindberg, N Carmoy, T Le Gall, A Fraix, M Berchel, C Lorilleux, ... Biomaterials 33 (26), 6240-6253, 2012 | 49 | 2012 |
| Structural Study of Hydrated/Dehydrated Manganese Thiophene-2,5-diphosphonate Metal Organic Frameworks, Mn2(O3P–C4H2S–PO3)·2H2O JM Rueff, O Perez, A Pautrat, N Barrier, GB Hix, S Hernot, ... Inorganic Chemistry 51 (19), 10251-10261, 2012 | 39 | 2012 |
| Cationic lipo-thiophosphoramidates for gene delivery: synthesis, physico-chemical characterization and gene transfection activity–comparison with lipo-phosphoramidates A Fraix, T Montier, N Carmoy, D Loizeau, L Burel-Deschamps, T Le Gall, ... Organic & Biomolecular Chemistry 9 (7), 2422-2432, 2011 | 36 | 2011 |
| Towards the syntheses of N‐H and N‐alkylated derivatives of meridianins B Corbel, FO Michaud, L Meijer, G Simon, H Couthon‐Gourves, ... Journal of heterocyclic chemistry 44 (4), 793-801, 2007 | 36 | 2007 |
| First general approach to cyclohex-3-ene-1, 1-bis (phosphonates) by Diels− Alder cycloaddition of tetraethyl vinylidenebis (phosphonate) to 1, 3-dienes R Ruzziconi, G Ricci, A Gioiello, H Couthon-Gourves, JP Gourves The Journal of Organic Chemistry 68 (3), 736-742, 2003 | 26 | 2003 |
| 3, 5-Diphosphonobenzoic Acid, a New Rigid Heterotrifunctional Building Block to Design Metal Organic Frameworks. Illustration with the Characterization of Cu5 [(O3P) 2-C6H3-CO2 … JM Rueff, O Perez, C Simon, C Lorilleux, H Couthon-Gourvès, PA Jaffres Crystal growth & design 9 (10), 4262-4268, 2009 | 23 | 2009 |
| DiGalactosyl-Glycero-Ether Lipid: Synthetic approaches and evaluation as SK3 channel inhibitor CM Sevrain, JP Haelters, A Chantôme, H Couthon-Gourvès, ... Organic & Biomolecular Chemistry 11 (27), 4479-4487, 2013 | 22 | 2013 |
| Synthesis of functionalized alkoxyalkylidene gem-bisphosphonates JP Haelters, H Couthon-Gourves, A Le Goff, G Simon, B Corbel, ... Tetrahedron 64 (27), 6537-6543, 2008 | 22 | 2008 |
| A NEW EFFICIENT SYNTHESIS OF ω-AMINOALKYLIDENE-1, 1-BISPHOSPHONATE TETRAETHYLESTERS JP Gourves, H Couthon, G Sturtz Phosphorus, Sulfur, and Silicon and the Related Elements 132 (1), 219-229, 1998 | 22 | 1998 |
| Singular interaction between an antimetastatic agent and the lipid bilayer: The Ohmline case FE Herrera, CM Sevrain, PA Jaffrès, H Couthon, A Grélard, EJ Dufourc, ... ACS omega 2 (10), 6361-6370, 2017 | 21 | 2017 |
| Synthesis of 3,4‐Dihydro‐2H‐pyrido[1,2‐b]isoindol‐1‐one and 3,4‐Dihydro‐2H‐pyrido[1,2‐b]pyrrolidin‐1‐one Functionalized at the C‐6 Position by an … JP Gourves, H Couthon, G Sturtz European journal of organic chemistry 1999 (12), 3489-3493, 1999 | 20 | 1999 |
| New disaccharide‐based ether lipids as SK3 ion channel inhibitors W Berthe, CM Sevrain, A Chantôme, AM Bouchet, M Gueguinou, ... ChemMedChem 11 (14), 1531-1539, 2016 | 19 | 2016 |
| Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection D Afonso, T Le Gall, H Couthon-Gourvès, A Grélard, S Prakash, ... Soft matter 12 (20), 4516-4520, 2016 | 18 | 2016 |
