| eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′ UTR A Wilczynska, SL Gillen, T Schmidt, HA Meijer, R Jukes-Jones, C Langlais, ... Genome Biology 20, 1-21, 2019 | 55 | 2019 |
| Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation M Šolman, A Ligabue, O Blaževitš, A Jaiswal, Y Zhou, H Liang, B Lectez, ... Elife 4, e08905, 2015 | 49 | 2015 |
| Homogeneous dual-parametric-coupled assay for simultaneous nucleotide exchange and KRAS/RAF-RBD interaction monitoring K Kopra, E Vuorinen, M Abreu-Blanco, Q Wang, V Eskonen, W Gillette, ... Analytical chemistry 92 (7), 4971-4979, 2020 | 43 | 2020 |
| Quenching resonance energy transfer (QRET): a single-label technique for inhibitor screening and interaction studies K Kopra, H Härmä New biotechnology 32 (6), 575-580, 2015 | 31 | 2015 |
| Non-competitive aptamer-based quenching resonance energy transfer assay for homogeneous growth factor quantification K Kopra, M Syrjänpää, P Hänninen, H Härmä Analyst 139 (8), 2016-2023, 2014 | 31 | 2014 |
| A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction K Kopra, A Ligabue, Q Wang, M Syrjänpää, O Blaževitš, S Veltel, ... Analytical and bioanalytical chemistry 406, 4147-4156, 2014 | 28 | 2014 |
| Sensitive label-free thermal stability assay for protein denaturation and protein–Ligand interaction studies E Vuorinen, S Valtonen, V Eskonen, T Kariniemi, J Jakovleva, K Kopra, ... Analytical chemistry 92 (5), 3512-3516, 2020 | 21 | 2020 |
| Nanomolar protein–protein interaction monitoring with a label-free Protein-Probe technique S Valtonen, E Vuorinen, T Kariniemi, V Eskonen, J Le Quesne, M Bushell, ... Analytical chemistry 92 (24), 15781-15788, 2020 | 18 | 2020 |
| High-throughput dual screening method for Ras activities and inhibitors K Kopra, AJ van Adrichem, OMH Salo-Ahen, J Peltonen, K Wennerberg, ... Analytical chemistry 89 (8), 4508-4516, 2017 | 17 | 2017 |
| Thermal shift assay for small GTPase stability screening: evaluation and suitability K Kopra, S Valtonen, R Mahran, JN Kapp, N Hassan, W Gillette, B Dennis, ... International journal of molecular sciences 23 (13), 7095, 2022 | 16 | 2022 |
| Time-resolved fluorescence-based assay for rapid detection of Escherichia coli J Kulpakko, K Kopra, P Hänninen Analytical biochemistry 470, 1-6, 2015 | 16 | 2015 |
| High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors G babu Manoharan, K Kopra, V Eskonen, H Härmä, D Abankwa Analytical biochemistry 572, 25-32, 2019 | 14 | 2019 |
| Toward universal protein post-translational modification detection in high throughput format H Härmä, N Tong-Ochoa, AJ van Adrichem, I Jelesarov, K Wennerberg, ... Chemical Communications 54 (23), 2910-2913, 2018 | 12 | 2018 |
| Aptamer-directed lanthanide chelate self-assembly for rapid thrombin detection H Päkkilä, S Blom, K Kopra, T Soukka Analyst 138 (17), 5107-5112, 2013 | 12 | 2013 |
| GTP-specific fab fragment-based GTPase activity assay K Kopra, A Rozwandowicz-Jansen, M Syrjanpaa, O Blazevits, A Ligabue, ... Analytical chemistry 87 (6), 3527-3534, 2015 | 11 | 2015 |
| Protease substrate-independent universal assay for monitoring digestion of native unmodified proteins E Vuorinen, S Valtonen, N Hassan, R Mahran, H Habib, M Malakoutikhah, ... International journal of molecular sciences 22 (12), 6362, 2021 | 10 | 2021 |
| Multiparametric Homogeneous Method for Identification of Ligand Binding to G Protein-Coupled Receptors: Receptor–Ligand Binding and β-Arrestin Assay K Kopra, M Kainulainen, P Mikkonen, A Rozwandowicz-Jansen, ... Analytical chemistry 85 (4), 2276-2281, 2013 | 10 | 2013 |
| Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies S Valtonen, E Vuorinen, V Eskonen, M Malakoutikhah, K Kopra, H Härmä MAbs 13 (1), 1955810, 2021 | 9 | 2021 |
| Homogeneous single-label tyrosine kinase activity assay for high throughput screening N Tong-Ochoa, K Kopra, M Syrjänpää, N Legrand, H Härmä Analytica chimica acta 897, 96-101, 2015 | 9 | 2015 |
| A homogeneous single-label quenching resonance energy transfer assay for a δ-opioid receptor–ligand using intact cells K Kopra, E Martikkala, P Hänninen, U Petäjä-Repo, H Härmä Analyst 138 (17), 4907-4914, 2013 | 9 | 2013 |
