Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk K Kearney, D Tomlinson, K Smith, R Ajjan Cardiovascular diabetology 16, 1-17, 2017 | 139 | 2017 |
Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity RA Ajjan, T Gamlen, KF Standeven, S Mughal, K Hess, KA Smith, ... Blood, The Journal of the American Society of Hematology 122 (1), 134-142, 2013 | 135 | 2013 |
A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3 K Hess, SH Alzahrani, M Mathai, V Schröder, AM Carter, G Howell, ... Diabetologia 55, 1103-1113, 2012 | 128 | 2012 |
Complement C3 is a novel plasma clot component with anti-fibrinolytic properties JM Howes, VR Richardson, KA Smith, V Schroeder, R Somani, A Shore, ... Diabetes and vascular disease research 9 (3), 216-225, 2012 | 91 | 2012 |
Adipose tissue inflammation: feeding the development of type 2 diabetes mellitus VR Richardson, KA Smith, AM Carter Immunobiology 218 (12), 1497-1504, 2013 | 81 | 2013 |
Interactions between factor XIII and the αC region of fibrinogen KA Smith, PJ Adamson, RJ Pease, JM Brown, AJ Balmforth, PA Cordell, ... Blood, The Journal of the American Society of Hematology 117 (12), 3460-3468, 2011 | 79 | 2011 |
Thyroid dysfunction and fibrin network structure: a mechanism for increased thrombotic risk in hyperthyroid individuals JMW Hooper, DJF Stuijver, SM Orme, B van Zaane, K Hess, VE Gerdes, ... The Journal of Clinical Endocrinology 97 (5), 1463-1473, 2012 | 73 | 2012 |
Cre/lox studies identify resident macrophages as the major source of circulating coagulation factor XIII-A CML Beckers, KR Simpson, KJ Griffin, JM Brown, LT Cheah, KA Smith, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1494-1502, 2017 | 57 | 2017 |
The activation peptide cleft exposed by thrombin cleavage of FXIII-A2 contains a recognition site for the fibrinogen α chain KA Smith, RJ Pease, CA Avery, JM Brown, PJ Adamson, EJ Cooke, ... Blood, The Journal of the American Society of Hematology 121 (11), 2117-2126, 2013 | 42 | 2013 |
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications KJ Kearney, N Pechlivani, R King, C Tiede, F Phoenix, R Cheah, ... Blood, The Journal of the American Society of Hematology 133 (11), 1233-1244, 2019 | 23 | 2019 |
Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII KN Mouapi, JD Bell, KA Smith, RAS Ariëns, H Philippou, MC Maurer Blood, The Journal of the American Society of Hematology 127 (18), 2241-2248, 2016 | 23 | 2016 |
Normal bone deposition occurs in mice deficient in factor XIII-A and transglutaminase 2 PA Cordell, LM Newell, KF Standeven, PJ Adamson, KR Simpson, ... Matrix Biology 43, 85-96, 2015 | 22 | 2015 |
Proteolytic and nonproteolytic activation mechanisms result in conformationally and functionally different forms of coagulation factor XIII A BA Anokhin, WL Dean, KA Smith, MJ Flick, RAS Ariëns, H Philippou, ... The FEBS journal 287 (3), 452-464, 2020 | 20 | 2020 |
(±) cis-bisamido epoxides: A novel series of potent FXIII-A inhibitors CA Avery, RJ Pease, K Smith, M Boothby, HM Buckley, PJ Grant, ... European journal of medicinal chemistry 98, 49-53, 2015 | 16 | 2015 |
The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit EL Hethershaw, PJ Adamson, KA Smith, WN Goldsberry, RJ Pease, ... Journal of Thrombosis and Haemostasis 16 (7), 1391-1401, 2018 | 11 | 2018 |
The inflammatory protein complement C3 is a novel substrate for factor XIII and impairs fibrin clot lysis AM Carter, V Schroeder, VR Polkinghorne, KA Smith, R Somani, ... Circulation 120 (suppl_18), S1099-S1099, 2009 | 2 | 2009 |
THROMBOSIS AND HEMOSTASIS A ffi mer proteins as a tool to modulate fi brinolysis, stabilize the blood clot, and reduce bleeding complications KJ Kearney, N Pechlivani, R King, C Tiede, F Phoenix, R Cheah, ... | | 2019 |
Fibrinogen alpha C (233-425): A model protein for characterizing cross-linking by the transglutaminase factor XIII KN Mouapi, J Bell, K Smith, R Ariens, H Philippou, M Maurer 253rd ACS National Meeting 253, 2017 | | 2017 |
Bottom-up approach to describe protein-protein interactions in a continuum mechanics biomolecular model of fibrin A Solernou, D Read, S Harris, O Harlen, K Smith, S Muench ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Transglutaminase Factor XIII Cross-Links Reactive Glutamines in Disordered Regions of Fibrinogen αC KN Mouapi, KA Smith, RAS Ariens, H Philippou, MC Maurer Biophysical Journal 110 (3), 549a, 2016 | | 2016 |