Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms JT Mattila, OO Ojo, D Kepka-Lenhart, S Marino, JH Kim, SY Eum, LE Via, ... The Journal of Immunology 191 (2), 773-784, 2013 | 373 | 2013 |
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ... Immunological reviews 285 (1), 147-167, 2018 | 236 | 2018 |
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection S Marino, NA Cilfone, JT Mattila, JJ Linderman, JAL Flynn, DE Kirschner Infection and immunity 83 (1), 324-338, 2015 | 204 | 2015 |
Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load CR Diedrich, JT Mattila, E Klein, C Janssen, J Phuah, TJ Sturgeon, ... PloS one 5 (3), e9611, 2010 | 200 | 2010 |
“Of mice and men”: arginine metabolism in macrophages AC Thomas, JT Mattila Frontiers in immunology 5, 479, 2014 | 197 | 2014 |
Immunology studies in non‐human primate models of tuberculosis JAL Flynn, HP Gideon, JT Mattila, PL Lin Immunological reviews 264 (1), 60-73, 2015 | 179 | 2015 |
Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis JY Phuah, JT Mattila, PL Lin, JAL Flynn The American journal of pathology 181 (2), 508-514, 2012 | 162 | 2012 |
Nitric oxide synthase: non-canonical expression patterns JT Mattila, AC Thomas Frontiers in immunology 5, 478, 2014 | 160 | 2014 |
CD4+ Regulatory T Cells in a Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection AM Green, JT Mattila, CL Bigbee, KS Bongers, P Ling Lin, JAL Flynn The Journal of infectious diseases 202 (4), 533-541, 2010 | 116 | 2010 |
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ... Immunity 55 (5), 827-846. e10, 2022 | 108 | 2022 |
Neutrophils express pro-and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques HP Gideon, J Phuah, BA Junecko, JT Mattila Mucosal immunology 12 (6), 1370-1381, 2019 | 103 | 2019 |
Simian immunodeficiency virus-induced changes in T cell cytokine responses in cynomolgus macaques with latent Mycobacterium tuberculosis infection are associated with timing of … JT Mattila, CR Diedrich, PL Lin, J Phuah, JAL Flynn The Journal of Immunology 186 (6), 3527-3537, 2011 | 90 | 2011 |
Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques SKC Ganchua, AM Cadena, P Maiello, HP Gideon, AJ Myers, BF Junecko, ... PLoS pathogens 14 (11), e1007337, 2018 | 87 | 2018 |
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity–mediated antimicrobial responses with caseation during Mycobacterium … NA Cilfone, CB Ford, S Marino, JT Mattila, HP Gideon, JAL Flynn, ... The Journal of Immunology 194 (2), 664-677, 2015 | 75 | 2015 |
Isolation of Cell Lines and a Rickettsial Endosymbiont from the Soft Tick Carios capensis (Acari: Argasidae: Ornithodorinae) JT Mattila, NY Burkhardt, HJ Hutcheson, UG Munderloh, TJ Kurtti Journal of medical entomology 44 (6), 1091-1101, 2007 | 72 | 2007 |
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment E Pienaar, NA Cilfone, PL Lin, V Dartois, JT Mattila, JR Butler, JAL Flynn, ... Journal of theoretical biology 367, 166-179, 2015 | 71 | 2015 |
Granzyme B‐expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis‐infected cynomolgus macaques JT Mattila, P Maiello, T Sun, LE Via, JAL Flynn Cellular microbiology 17 (8), 1085-1097, 2015 | 69 | 2015 |
Active transforming growth factor-β is associated with phenotypic changes in granulomas after drug treatment in pulmonary tuberculosis RM DiFazio, JT Mattila, EC Klein, LR Cirrincione, M Howard, EA Wong, ... Fibrogenesis & tissue repair 9, 1-11, 2016 | 66 | 2016 |
Predicting lymph node output efficiency using systems biology C Gong, JT Mattila, M Miller, JAL Flynn, JJ Linderman, D Kirschner Journal of theoretical biology 335, 169-184, 2013 | 59 | 2013 |
IL-10 impairs local immune response in lung granulomas and lymph nodes during early Mycobacterium tuberculosis infection EA Wong, S Evans, CR Kraus, KD Engelman, P Maiello, WJ Flores, ... The Journal of Immunology 204 (3), 644-659, 2020 | 56 | 2020 |