Formulation of L-asparaginase-loaded poly (lactide-co-glycolide) nanoparticles: influence of polymer properties on enzyme loading, activity and in vitro release MM Gaspar, D Blanco, MEM Cruz, MJ Alonso Journal of controlled release 52 (1-2), 53-62, 1998 | 237 | 1998 |
Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems CO Silva, JO Pinho, JM Lopes, AJ Almeida, MM Gaspar, C Reis Pharmaceutics 11 (1), 22, 2019 | 175 | 2019 |
Rifabutin encapsulated in liposomes exhibits increased therapeutic activity in a model of disseminated tuberculosis MM Gaspar, A Cruz, AF Penha, J Reymão, AC Sousa, CV Eleutério, ... International journal of antimicrobial agents 31 (1), 37-45, 2008 | 134 | 2008 |
Activation of necroptosis in human and experimental cholestasis MB Afonso, PM Rodrigues, AL Simão, D Ofengeim, T Carvalho, ... Cell Death & Disease 7 (9), e2390-e2390, 2016 | 123 | 2016 |
Liposomes as antibiotic delivery systems: a promising nanotechnological strategy against antimicrobial resistance M Ferreira, M Ogren, JNR Dias, M Silva, S Gil, L Tavares, F Aires-da-Silva, ... Molecules 26 (7), 2047, 2021 | 122 | 2021 |
Biological characterization of L-asparaginase liposomal formulations MM Gaspar, R Perez-Soler, MEM Cruz Cancer chemotherapy and pharmacology 38, 373-377, 1996 | 114 | 1996 |
miRNA-21 ablation protects against liver injury and necroptosis in cholestasis MB Afonso, PM Rodrigues, AL Simão, MM Gaspar, T Carvalho, ... Cell Death & Differentiation 25 (5), 857-872, 2018 | 110 | 2018 |
The secretome derived from 3D-cultured umbilical cord tissue MSCs counteracts manifestations typifying rheumatoid arthritis JP Miranda, SP Camões, MM Gaspar, JS Rodrigues, M Carvalheiro, ... Frontiers in immunology 10, 18, 2019 | 84 | 2019 |
Enzymosomes with surface-exposed superoxide dismutase: in vivo behaviour and therapeutic activity in a model of adjuvant arthritis MM Gaspar, OC Boerman, P Laverman, ML Corvo, G Storm, MEM Cruz Journal of Controlled Release 117 (2), 186-195, 2007 | 83 | 2007 |
Targeted delivery of transferrin-conjugated liposomes to an orthotopic model of lung cancer in nude rats MM Gaspar, A Radomska, OL Gobbo, U Bakowsky, MW Radomski, ... Journal of aerosol medicine and pulmonary drug delivery 25 (6), 310-318, 2012 | 79 | 2012 |
Inhaled liposomes–current strategies and future challenges MM Gaspar, U Bakowsky, C Ehrhardt Journal of Biomedical Nanotechnology 4 (3), 245-257, 2008 | 78 | 2008 |
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease MB Afonso, PM Rodrigues, M Mateus-Pinheiro, AL Simão, MM Gaspar, ... Gut 70 (12), 2359-2372, 2021 | 77 | 2021 |
Microencapsulated solid lipid nanoparticles as a hybrid platform for pulmonary antibiotic delivery DP Gaspar, MM Gaspar, CV Eleuterio, A Grenha, M Blanco, ... Molecular Pharmaceutics 14 (9), 2977-2990, 2017 | 74 | 2017 |
Developments on drug delivery systems for the treatment of mycobacterial infections MM Gaspar, A Cruz, AG Fraga, AG Castro, MEM Cruz, J Pedrosa Current Topics in Medicinal Chemistry 8 (7), 579-591, 2008 | 69 | 2008 |
Therapeutic Efficacy of Liposomal Rifabutin in a Mycobacterium avium Model of Infection MM Gaspar, S Neves, F Portaels, J Pedrosa, MT Silva, MEM Cruz Antimicrobial agents and chemotherapy 44 (9), 2424-2430, 2000 | 65 | 2000 |
Melanoma management: from epidemiology to treatment and latest advances J Lopes, CMP Rodrigues, MM Gaspar, CP Reis Cancers 14 (19), 4652, 2022 | 62 | 2022 |
Liposomal superoxide dismutases and their use in the treatment of experimental arthritis M Eugénia, M Cruz, MM Gaspar, M Bárbara, F Martins, ML Corvo Methods in enzymology 391, 395-413, 2005 | 62 | 2005 |
Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells M Nave, RE Castro, CMP Rodrigues, A Casini, G Soveral, MM Gaspar Nanomedicine 11 (14), 1817-1830, 2016 | 61 | 2016 |
Targeted delivery of paromomycin in murine infectious diseases through association to nano lipid systems MM Gaspar, S Calado, J Pereira, H Ferronha, I Correia, H Castro, ... Nanomedicine: Nanotechnology, Biology and Medicine 11 (7), 1851-1860, 2015 | 61 | 2015 |
Liposomal L-asparaginase: in vitro evaluation MEM Cruz, MM Gaspar, F Lopes, JS Jorge, R Perez-Soler International journal of pharmaceutics 96 (1-3), 67-77, 1993 | 60 | 1993 |