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Nathanyal J. Truax
Nathanyal J. Truax
Research Scientist, Vertex Pharmaceuticals
在 vrtx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Bridging the gap between natural product synthesis and drug discovery
NJ Truax, D Romo
Natural product reports 37 (11), 1436-1453, 2020
712020
Synthesis of Benzo[a]carbazoles and an Indolo[2,3-a]carbazole from 3-Aryltetramic Acids
NJ Truax, F Banales Mejia, DO Kwansare, MM Lafferty, MH Kean, ...
The Journal of Organic Chemistry 81 (15), 6808-6815, 2016
282016
Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Sinularia Natural Product Tricyclic Cores
JN Truax, S Ayinde, K Van, JO Liu, D Romo
Organic Letters 21 (18), 7394-7399, 2019
242019
Total Synthesis of Rameswaralide Utilizing a Pharmacophore-Directed Retrosynthetic Strategy
NJ Truax, S Ayinde, JO Liu, D Romo
Journal of the American Chemical Society 144 (40), 18575-18585, 2022
212022
Synthesis and evaluation of the anti-proliferative activity of diaryl-3-pyrrolin-2-ones and fused analogs
P Mowery, FB Mejia, CL Franceschi, MH Kean, DO Kwansare, ...
Bioorganic & Medicinal Chemistry Letters 27 (2), 191-195, 2017
172017
Discovery of an indole-substituted furanone with tubulin polymerization inhibition activity
P Mowery, MM Filkorn, B Hurysz, DO Kwansare, MM Lafferty, ...
Bioorganic & Medicinal Chemistry Letters 41, 127991, 2021
92021
Total Synthesis of Dragocins A− C through Electrochemical Cyclization
BP Smith, NJ Truax, AS Pollatos, M Meanwell, P Bedekar, ...
Angewandte Chemie 136 (19), e202401107, 2024
52024
Necator americanus Ancylostoma Secreted Protein-2 (Na-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site
O El Atab, R Darwiche, NJ Truax, R Schneiter, KG Hull, D Romo, ...
Frontiers in Chemistry 8, 608296, 2020
52020
Lewis Acid Mediated Addition of Indoles and Alcohols to Tetronic Acid and Tetramic Acids
FB Mejia, MM Lafferty, SJ Melvin, NJ Truax, MH Kean, ET Pelkey
Synlett 28 (02), 260-264, 2017
32017
Necator americanus Ancylostoma secreted protein-2 (Na-ASP-2) selectively binds an ascaroside (ascr# 3)
O El Atab, R Darwiche, NJ Truax, R Schneiter, KG Hull, D Romo, ...
bioRxiv, 2020.08. 07.224964, 2020
12020
Simple, Enantiocontrolled Azetidine Library Synthesis via Strain Release Functionalization of 1-Azabicyclobutanes
M Bielecki, M Nassir, HA Sharma, NJ Truax, N Raheja, TM Thompson, ...
2024
Total Synthesis of Dragocins A–C via Electrochemical Cyclization
B Smith, N Truax, A Pollatos, M Meanwell, P Bedekar, A Garrido-Castro, ...
2024
Total Synthesis of Rameswaralide Utilizing a Pharmacophore Directed Retrosynthetic Approach
NJ Truax
Baylor University, 2022
2022
Natural Product Reports
NJ Truax, D Romo
2020
Pharmacophore-Directed Retrosynthesis: A Function-Oriented Approach to Natural Product Total Synthesis
D Romo, H Xue, N Truax, K Van, Y Tao
MARINE DRUGS 18 (1), 2020
2020
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