Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss W Yu, L Zhong, L Yao, Y Wei, T Gui, Z Li, H Kim, N Holdreith, X Jiang, ... The Journal of clinical investigation 131 (2), 2021 | 131 | 2021 |
Targeting cartilage EGFR pathway for osteoarthritis treatment Y Wei, L Luo, T Gui, F Yu, L Yan, L Yao, L Zhong, W Yu, B Han, JM Patel, ... Science translational medicine 13 (576), eabb3946, 2021 | 107 | 2021 |
Metabolic syndrome increases the risk for knee osteoarthritis: a meta‐analysis H Wang, Y Cheng, D Shao, J Chen, Y Sang, T Gui, S Luo, J Li, C Chen, ... Evidence‐Based Complementary and Alternative Medicine 2016 (1), 7242478, 2016 | 64 | 2016 |
The BET bromodomain inhibitor JQ1 suppresses chondrosarcoma cell growth via regulation of YAP/p21/c‐Myc signaling HT Zhang, T Gui, Y Sang, J Yang, YH Li, GH Liang, T Li, QY He, ZG Zha Journal of Cellular Biochemistry 118 (8), 2182-2192, 2017 | 56 | 2017 |
Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy T Gui, L Luo, B Chhay, L Zhong, Y Wei, L Yao, W Yu, J Li, CL Nelson, ... Biomaterials 283, 121437, 2022 | 52 | 2022 |
Phospholipase A2 inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression Y Wei, L Yan, L Luo, T Gui, B Jang, A Amirshaghaghi, T You, A Tsourkas, ... Science advances 7 (15), eabe6374, 2021 | 42 | 2021 |
Knee muscle atrophy is a risk factor for development of knee osteoarthritis in a rat model J Xu, G She, T Gui, H Hou, J Li, Y Chen, Z Zha Journal of orthopaedic translation 22, 67-72, 2020 | 22 | 2020 |
Andrographolide induces cell cycle arrest and apoptosis of chondrosarcoma by targeting TCF‐1/SOX9 axis HT Zhang, J Yang, GH Liang, XJ Gao, Y Sang, T Gui, ZJ Liang, MS Tam, ... Journal of Cellular Biochemistry 118 (12), 4575-4586, 2017 | 22 | 2017 |
Csf1 from marrow adipogenic precursors is required for osteoclast formation and hematopoiesis in bone L Zhong, J Lu, J Fang, L Yao, W Yu, T Gui, M Duffy, N Holdreith, ... Elife 12, e82112, 2023 | 20 | 2023 |
EGFR signaling is required for maintaining adult cartilage homeostasis and attenuating osteoarthritis progression Y Wei, X Ma, H Sun, T Gui, J Li, L Yao, L Zhong, W Yu, B Han, CL Nelson, ... Journal of Bone and Mineral Research 37 (5), 1012-1023, 2020 | 20 | 2020 |
Sequential targeting of YAP1 and p21 enhances the elimination of senescent cells induced by the BET inhibitor JQ1 HT Zhang, T Gui, RX Liu, KL Tong, CJ Wu, Z Li, X Huang, QT Xu, J Yang, ... Cell Death & Disease 12 (1), 121, 2021 | 19 | 2021 |
The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair Y Wei, H Sun, T Gui, L Yao, L Zhong, W Yu, SJ Heo, L Han, NA Dyment, ... Elife 10, e62917, 2021 | 18 | 2021 |
Elevated expression of ICAM‐1 in synovium is associated with early inflammatory response for cartilage degeneration in type 2 diabetes mellitus T Gui, YK Lin, SW Huan, YH Li, BH Wang, J Yang, RH Gu, Q Liu, ZY Li, ... Journal of Cellular Biochemistry 120 (8), 13177-13186, 2019 | 13 | 2019 |
Activating EGFR signaling attenuates osteoarthritis development following loading injury in mice T Gui, Y Wei, L Luo, J Li, L Zhong, L Yao, F Beier, CL Nelson, A Tsourkas, ... Journal of Bone and Mineral Research 37 (12), 2498-2511, 2020 | 12 | 2020 |
YAP/miR-524-5p axis negatively regulates TXNIP expression to promote chondrosarcoma cell growth RX Liu, W Tang, BY Zheng, Y Yang, ZY Li, T Gui, HT Zhang, N Liu, ... Biochemical and Biophysical Research Communications 590, 20-26, 2022 | 9 | 2022 |
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation L Zhong, L Yao, N Holdreith, W Yu, T Gui, Z Miao, Y Elkaim, M Li, Y Gong, ... JCI insight 7 (7), 2022 | 8 | 2022 |
Combination BET family protein and HDAC inhibition synergistically elicits chondrosarcoma cell apoptosis through RAD51-related DNA damage repair S Huan, T Gui, Q Xu, S Zhuang, Z Li, Y Shi, J Lin, B Gong, G Miao, M Tam, ... Cancer management and research, 4429-4439, 2020 | 7 | 2020 |
Bone marrow adipogenic lineage precursors (MALPs) promote osteoclastogenesis in bone remodeling and pathologic bone loss W Yu, L Zhong, L Yao, Y Wei, T Gui, Z Li, H Kim, N Dyment, XS Liu, ... bioRxiv, 2020.08. 01.231829, 2020 | 6 | 2020 |
Targeting YAP1‐regulated glycolysis in fibroblast‐like synoviocytes impairs macrophage infiltration to ameliorate diabetic osteoarthritis progression J Yang, S Li, Z Li, L Yao, M Liu, KL Tong, Q Xu, B Yu, R Peng, T Gui, ... Advanced Science 11 (5), 2304617, 2024 | 5 | 2024 |
Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis J Li, T Gui, L Yao, H Guo, YL Lin, J Lu, M Duffy, M Zgonis, R Mauck, ... Journal of Bone and Mineral Research 39 (2), 161-176, 2024 | 4 | 2024 |