Facile Benzo-Ring Construction via Palladium-Catalyzed Functionalization of Unactivated sp3 C−H Bonds under Mild Reaction Conditions Y Feng, Y Wang, B Landgraf, S Liu, G Chen Organic Letters 12 (15), 3414-3417, 2010 | 170 | 2010 |
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation AD White, KA Peña, LJ Clark, CS Maria, S Liu, FG Jean-Alphonse, JY Lee, ... Science signaling 14 (703), eabc5944, 2021 | 54 | 2021 |
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome KY Lai, SRG Galan, Y Zeng, TH Zhou, C He, R Raj, J Riedl, S Liu, ... Cell 184 (10), 2680-2695. e26, 2021 | 45 | 2021 |
Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR AD White, FG Jean-Alphonse, F Fang, KA Peña, S Liu, GM König, A Inoue, ... Proceedings of the National Academy of Sciences 117 (13), 7455-7460, 2020 | 41 | 2020 |
Receptor selectivity from minimal backbone modification of a polypeptide agonist S Liu, RW Cheloha, T Watanabe, TJ Gardella, SH Gellman Proceedings of the National Academy of Sciences 115 (49), 12383-12388, 2018 | 36 | 2018 |
Use of backbone modification to enlarge the spatiotemporal diversity of parathyroid hormone receptor-1 signaling via biased agonism S Liu, FG Jean-Alphonse, AD White, D Wootten, PM Sexton, TJ Gardella, ... Journal of the American Chemical Society 141 (37), 14486-14490, 2019 | 30 | 2019 |
Preparation of β2-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy S Liu, SH Gellman The Journal of organic chemistry 85 (3), 1718-1724, 2020 | 13 | 2020 |
The mechanism of thia-Michael addition catalyzed by LanC enzymes C Ongpipattanakul, S Liu, Y Luo, SK Nair, WA van der Donk Proceedings of the National Academy of Sciences 120 (3), e2217523120, 2023 | 8 | 2023 |
Recognition of class II MHC peptide ligands that contain β-amino acids RW Cheloha, AW Woodham, D Bousbaine, T Wang, S Liu, J Sidney, ... The Journal of Immunology 203 (6), 1619-1628, 2019 | 8 | 2019 |
Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo S Liu, Z Yu, EJ Daley, CA Bingman, AT Bruchs, TJ Gardella, SH Gellman Proceedings of the National Academy of Sciences 119 (48), e2212736119, 2022 | 3 | 2022 |
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants S Liu, EJ Daley, LML Tran, Z Yu, M Reyes, T Dean, A Khatri, PM Levine, ... Journal of the American Chemical Society 146 (10), 6522-6529, 2024 | | 2024 |
Analogues of parathyroid hormone (1-34) that function as agonists of the parathyroid hormone receptor-1 and display modified activity profiles SH Gellman, S Liu, TJ Gardella US Patent 11,780,901, 2023 | | 2023 |
Location Bias in cAMP Signaling and its effects on Parathyroid Hormone Receptor Biological Effectiveness K Pena, A White, L Clark, S Liu, F Jean‐Alphonse, T Gardella, K Xiao, ... The FASEB Journal 35, 2021 | | 2021 |