| A crucial role for adipose tissue p53 in the regulation of insulin resistance T Minamino, M Orimo, I Shimizu, T Kunieda, M Yokoyama, T Ito, A Nojima, ... Nature medicine 15 (9), 1082-1087, 2009 | 954 | 2009 |
| Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice A Bitto, TK Ito, VV Pineda, NJ LeTexier, HZ Huang, E Sutlief, H Tung, ... elife 5, e16351, 2016 | 401 | 2016 |
| p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure I Shimizu, Y Yoshida, T Katsuno, K Tateno, S Okada, J Moriya, ... Cell metabolism 15 (1), 51-64, 2012 | 210 | 2012 |
| In vivo characterization of bone marrow–derived fibroblasts recruited into fibrotic lesions G Ishii, T Sangai, K Sugiyama, T Ito, T Hasebe, Y Endoh, J Magae, ... Stem cells 23 (5), 699-706, 2005 | 196 | 2005 |
| The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells TK Ito, G Ishii, H Chiba, A Ochiai Oncogene 26 (51), 7194-7203, 2007 | 182 | 2007 |
| Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system–mediated pathway S Okada, M Yokoyama, H Toko, K Tateno, J Moriya, I Shimizu, A Nojima, ... Arteriosclerosis, thrombosis, and vascular biology 32 (8), 1902-1909, 2012 | 175 | 2012 |
| Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation: podoplanin in fibroblast functions for tumor progression A Hoshino, G Ishii, T Ito, K Aoyagi, Y Ohtaki, K Nagai, H Sasaki, A Ochiai Cancer research 71 (14), 4769-4779, 2011 | 171 | 2011 |
| Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells TK Ito, G Ishii, S Saito, K Yano, A Hoshino, T Suzuki, A Ochiai Blood, The Journal of the American Society of Hematology 113 (10), 2363-2369, 2009 | 105 | 2009 |
| Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow‐derived endothelial cells and myofibroblasts in cancer‐induced stroma T Sangai, G Ishii, K Kodama, S Miyamoto, Y Aoyagi, T Ito, J Magae, ... International journal of cancer 115 (6), 885-892, 2005 | 86 | 2005 |
| LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis D Ren, J Chen, Z Li, H Yan, Y Yin, D Wo, J Zhang, L Ao, B Chen, TK Ito, ... Nature communications 6 (1), 6906, 2015 | 68 | 2015 |
| A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis TK Ito, M Yokoyama, Y Yoshida, A Nojima, H Kassai, K Oishi, S Okada, ... PloS one 9 (7), e102186, 2014 | 59 | 2014 |
| In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma G Ishii, T Sangai, T Ito, T Hasebe, Y Endoh, H Sasaki, K Harigaya, ... International journal of cancer 117 (2), 212-220, 2005 | 53 | 2005 |
| Involvement of telomerase reverse transcriptase in heterochromatin maintenance Y Maida, M Yasukawa, N Okamoto, S Ohka, K Kinoshita, Y Totoki, TK Ito, ... Molecular and Cellular Biology 34 (9), 1576-1593, 2014 | 52 | 2014 |
| Presence of human circulating progenitor cells for cancer stromal fibroblasts in the blood of lung cancer patients G Ishii, TK Ito, K Aoyagi, H Fujimoto, H Chiba, T Hasebe, S Fujii, K Nagai, ... Stem cells 25 (6), 1469-1477, 2007 | 41 | 2007 |
| Preferential incorporation of administered eicosapentaenoic acid into thin-cap atherosclerotic plaques T Sato, M Horikawa, S Takei, F Yamazaki, TK Ito, T Kondo, T Sakurai, ... Arteriosclerosis, thrombosis, and vascular biology 39 (9), 1802-1816, 2019 | 38 | 2019 |
| Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells: a novel character of tumor educated fibroblasts G Ishii, H Hashimoto, K Asada, T Ito, A Hoshino, S Fujii, M Kojima, ... International journal of oncology 37 (2), 317-325, 2010 | 34 | 2010 |
| PKC downregulation upon rapamycin treatment attenuates mitochondrial disease M Martin-Perez, AS Grillo, TK Ito, AS Valente, J Han, SW Entwisle, ... Nature metabolism 2 (12), 1472-1481, 2020 | 32 | 2020 |
| Dietary intake of green nut oil or DHA ameliorates DHA distribution in the brain of a mouse model of dementia accompanied by memory recovery E Takeyama, A Islam, N Watanabe, H Tsubaki, M Fukushima, MA Mamun, ... Nutrients 11 (10), 2371, 2019 | 23 | 2019 |
| Hepatic S6K1 partially regulates lifespan of mice with mitochondrial complex I deficiency TK Ito, C Lu, J Khan, Q Nguyen, HZ Huang, D Kim, J Phillips, J Tan, Y Lee, ... Frontiers in genetics 8, 113, 2017 | 23 | 2017 |
| Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway D Kinoshita, A Nagasawa, I Shimizu, TK Ito, Y Yoshida, M Tsuchida, ... Oncotarget 8 (21), 34045, 2017 | 20 | 2017 |
