Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins M Pirazzini, D Azarnia Tehran, G Zanetti, A Megighian, M Scorzeto, S Fillo, ... Cell reports 8 (6), 1870-1878, 2014 | 127 | 2014 |
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments M Pirazzini, D Azarnia Tehran, O Leka, G Zanetti, O Rossetto, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (3), 467-474, 2016 | 110 | 2016 |
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain I Zornetta, D Azarnia Tehran, G Arrigoni, F Anniballi, L Bano, O Leka, ... Scientific Reports 6, 2016 | 106 | 2016 |
Novel Botulinum Neurotoxins: Exploring Underneath the Iceberg Tip D Azarnia Tehran, M Pirazzini Toxins 10 (5), 190, 2018 | 70 | 2018 |
Presynaptic endocytic factors in autophagy and neurodegeneration D Azarnia Tehran, M Kuijpers, V Haucke Current opinion in neurobiology 48, 153-159, 2018 | 57* | 2018 |
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals D Azarnia Tehran, M Pirazzini, O Leka, A Mattarei, F Lista, T Binz, ... Cellular microbiology, 2017 | 47 | 2017 |
The thioredoxin reductase–Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles M Pirazzini, D Azarnia Tehran, G Zanetti, F Lista, T Binz, CC Shone, ... Toxicon 107, 32-36, 2015 | 45 | 2015 |
Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism G Zanetti, D Azarnia Tehran, M Pirazzini, T Binz, CC Shone, S Fillo, ... Biochemical pharmacology 98 (3), 522-530, 2015 | 38 | 2015 |
A novel inhibitor prevents the peripheral neuroparalysis of botulinum neurotoxins D Azarnia Tehran, G Zanetti, O Leka, F Lista, S Fillo, T Binz, CC Shone, ... Scientific reports 5, 17513, 2015 | 37 | 2015 |
Endocytic adaptor proteins in health and disease: lessons from model organisms and human mutations D Azarnia Tehran, T Lopez-Hernandez, T Maritzen Cells 8 (11), 1345, 2019 | 34 | 2019 |
The axonal endolysosomal and autophagic systems M Kuijpers, D Azarnia Tehran, V Haucke, T Soykan Journal of Neurochemistry 158 (3), 589-602, 2021 | 32 | 2021 |
Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals M Pirazzini, D Azarnia Tehran, G Zanetti, O Rossetto, C Montecucco Toxicon, 2017 | 30 | 2017 |
Genomic characterization of Italian Clostridium botulinum group I strains F Giordani, S Fillo, A Anselmo, AM Palozzi, A Fortunato, B Gentile, ... Infection, Genetics and Evolution 36, 62-71, 2015 | 30 | 2015 |
Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity D Azarnia Tehran, G Kochlamazashvili, NP Pampaloni, S Sposini, ... Science Advances 8 (21), eabl5032, 2022 | 17 | 2022 |
Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells from Intoxication L Schnell, AK Mittler, A Mattarei, D Azarnia Tehran, C Montecucco, ... Toxins 8 (7), 221, 2016 | 13 | 2016 |
Multiple-locus variable number of tandem repeat analysis as a tool for molecular epidemiology of botulism: The Italian experience F Anniballi, S Fillo, F Giordani, B Auricchio, D Azarnia Tehran, ... Infection, Genetics and Evolution 46, 28-32, 2016 | 11 | 2016 |
Preparation of Cerebellum Granule Neurons from Mouse or Rat Pups and Evaluation of Clostridial Neurotoxin Activity and Their Inhibitors by Western Blot and Immunohistochemistry D Azarnia Tehran, M Pirazzini | 10* | 2018 |
EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin L Schnell, AK Mittler, M Sadi, MR Popoff, C Schwan, K Aktories, A Mattarei, ... Toxins 8 (4), 101, 2016 | 8 | 2016 |
Endocytic proteins: An expanding repertoire of presynaptic functions D Azarnia Tehran, T Maritzen Current Opinion in Neurobiology 73, 102519, 2022 | 7* | 2022 |
The booming field of botulinum neurotoxins O Rossetto, M Pirazzini, G Zanetti, D Azarnia Tehran, F Lista, T Binz, ... Toxicon 158, S14-S14, 2019 | | 2019 |