| Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma RWK Chiu, KCA Chan, Y Gao, VYM Lau, W Zheng, TY Leung, CHF Foo, ... Proceedings of the National Academy of Sciences 105 (51), 20458-20463, 2008 | 1445 | 2008 |
| Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus YMD Lo, KCA Chan, H Sun, EZ Chen, P Jiang, FMF Lun, YW Zheng, ... Science translational medicine 2 (61), 61ra91-61ra91, 2010 | 1390 | 2010 |
| Detection and characterization of placental microRNAs in maternal plasma SSC Chim, TKF Shing, ECW Hung, T Leung, T Lau, RWK Chiu, ... Clinical chemistry 54 (3), 482-490, 2008 | 1211 | 2008 |
| Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study RWK Chiu, R Akolekar, YWL Zheng, TY Leung, H Sun, KCA Chan, ... Bmj 342, 2011 | 1134 | 2011 |
| Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients N Lee, KCA Chan, DS Hui, EKO Ng, A Wu, RWK Chiu, VWS Wong, ... Journal of clinical virology 31 (4), 304-309, 2004 | 719 | 2004 |
| Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients P Jiang, CWM Chan, KCA Chan, SH Cheng, J Wong, VWS Wong, ... Proceedings of the National Academy of Sciences 112 (11), E1317-E1325, 2015 | 715 | 2015 |
| Predominant hematopoietic origin of cell-free DNA in plasma and serum after sex-mismatched bone marrow transplantation YYN Lui, KW Chik, RWK Chiu, CY Ho, CWK Lam, YMD Lo Clinical chemistry 48 (3), 421-427, 2002 | 713 | 2002 |
| Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments K Sun, P Jiang, KCA Chan, J Wong, YKY Cheng, RHS Liang, W Chan, ... Proceedings of the National Academy of Sciences 112 (40), E5503-E5512, 2015 | 710 | 2015 |
| Digital PCR for the molecular detection of fetal chromosomal aneuploidy YMD Lo, FMF Lun, KCA Chan, NBY Tsui, KC Chong, TK Lau, TY Leung, ... Proceedings of the National Academy of Sciences 104 (32), 13116-13121, 2007 | 686 | 2007 |
| Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection YMD Lo, NBY Tsui, RWK Chiu, TK Lau, TN Leung, MMS Heung, ... Nature medicine 13 (2), 218-223, 2007 | 663 | 2007 |
| Analysis of plasma Epstein–Barr virus DNA to screen for nasopharyngeal cancer KCA Chan, JKS Woo, A King, BCY Zee, WKJ Lam, SL Chan, SWI Chu, ... New England Journal of Medicine 377 (6), 513-522, 2017 | 655 | 2017 |
| Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma FMF Lun, RWK Chiu, KC Allen Chan, T Yeung Leung, T Kin Lau, ... Clinical chemistry 54 (10), 1664-1672, 2008 | 655 | 2008 |
| Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing KCA Chan, P Jiang, YWL Zheng, GJW Liao, H Sun, J Wong, SSN Siu, ... Clinical chemistry 59 (1), 211-224, 2013 | 604 | 2013 |
| mRNA of placental origin is readily detectable in maternal plasma EKO Ng, NBY Tsui, TK Lau, TN Leung, RWK Chiu, NS Panesar, LCW Lit, ... Proceedings of the National Academy of Sciences 100 (8), 4748-4753, 2003 | 563 | 2003 |
| Effects of blood-processing protocols on fetal and total DNA quantification in maternal plasma RWK Chiu, LLM Poon, TK Lau, TN Leung, EMC Wong, YMD Lo Clinical chemistry 47 (9), 1607-1613, 2001 | 554 | 2001 |
| Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma FMF Lun, NBY Tsui, KCA Chan, TY Leung, TK Lau, P Charoenkwan, ... Proceedings of the National Academy of Sciences 105 (50), 19920-19925, 2008 | 532 | 2008 |
| Detection of the placental epigenetic signature of the maspin gene in maternal plasma SSC Chim, YK Tong, RWK Chiu, TK Lau, TN Leung, LYS Chan, ... Proceedings of the National Academy of Sciences 102 (41), 14753-14758, 2005 | 509 | 2005 |
| Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing EZ Chen, RWK Chiu, H Sun, R Akolekar, KCA Chan, TY Leung, P Jiang, ... PloS one 6 (7), e21791, 2011 | 495 | 2011 |
| Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing KCA Chan, P Jiang, CWM Chan, K Sun, J Wong, EP Hui, SL Chan, ... Proceedings of the National Academy of Sciences 110 (47), 18761-18768, 2013 | 480 | 2013 |
| Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis KCA Chan, C Ding, A Gerovassili, SW Yeung, RWK Chiu, TN Leung, ... Clinical chemistry 52 (12), 2211-2218, 2006 | 478 | 2006 |
