| Nucleoside derived antibiotics to fight microbial drug resistance: new utilities for an established class of drugs? M Serpi, V Ferrari, F Pertusati Journal of medicinal chemistry 59 (23), 10343-10382, 2016 | 131 | 2016 |
| Phosphoramidates and phosphonamidates (ProTides) with antiviral activity M Slusarczyk, M Serpi, F Pertusati Antiviral Chemistry and Chemotherapy 26, 2040206618775243, 2018 | 119 | 2018 |
| Polyfluorinated groups in medicinal chemistry M Bassetto, S Ferla, F Pertusati Future medicinal chemistry 7 (4), 527-546, 2015 | 113 | 2015 |
| λ5-Phosphorus-Containing α-Diazo Compounds: A Valuable Tool for Accessing Phosphorus-Functionalized Molecules M Marinozzi, F Pertusati, M Serpi Chemical reviews 116 (22), 13991-14055, 2016 | 112 | 2016 |
| Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer M Bassetto, S Ferla, F Pertusati, S Kandil, AD Westwell, A Brancale, ... European journal of medicinal chemistry 118, 230-243, 2016 | 70 | 2016 |
| Diastereoselective synthesis of P-chirogenic phosphoramidate prodrugs of nucleoside analogues (ProTides) via copper catalysed reaction F Pertusati, C McGuigan Chemical Communications 51 (38), 8070-8073, 2015 | 53 | 2015 |
| ProTides of N-(3-(5-(2′-deoxyuridine)) prop-2-ynyl) octanamide as potential anti-tubercular and anti-viral agents C McGuigan, M Derudas, B Gonczy, K Hinsinger, S Kandil, F Pertusati, ... Bioorganic & medicinal chemistry 22 (9), 2816-2824, 2014 | 42 | 2014 |
| Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides C McGuigan, C Bourdin, M Derudas, N Hamon, K Hinsinger, S Kandil, ... European journal of medicinal chemistry 70, 326-340, 2013 | 42 | 2013 |
| Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity KS Toti, M Derudas, F Pertusati, D Sinnaeve, F Van den Broeck, ... The Journal of organic chemistry 79 (11), 5097-5112, 2014 | 37 | 2014 |
| Synthesis of phosphoramidate prodrugs: ProTide approach M Serpi, K Madela, F Pertusati, M Slusarczyk Current protocols in nucleic acid chemistry 53 (1), 15.5. 1-15.5. 15, 2013 | 36 | 2013 |
| PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer F Pertusati, K Hinsinger, ÁS Flynn, N Powell, A Tristram, J Balzarini, ... European journal of medicinal chemistry 78, 259-268, 2014 | 34 | 2014 |
| An overview of ProTide technology and its implications to drug discovery M Serpi, F Pertusati Expert Opinion on Drug Discovery, 2021 | 31 | 2021 |
| Anti‐flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues C McGuigan, M Serpi, M Slusarczyk, V Ferrari, F Pertusati, S Meneghesso, ... ChemistryOpen 5 (3), 227, 2016 | 25 | 2016 |
| A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative … F Pertusati, S Ferla, M Bassetto, A Brancale, S Khandil, AD Westwell, ... European journal of medicinal chemistry 180, 1-14, 2019 | 24 | 2019 |
| Process for preparing nucleoside prodrugs C McGuigan, F Pertusati US Patent 10,005,810, 2018 | 23 | 2018 |
| Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy F Pertusati, S Serafini, N Albadry, R Snoeck, G Andrei Antiviral research 143, 262-268, 2017 | 23 | 2017 |
| Kinase-independent phosphoramidate S1P1 receptor agonist benzyl ether derivatives E James, F Pertusati, A Brancale, C McGuigan Bioorganic & medicinal chemistry letters 27 (6), 1371-1378, 2017 | 18 | 2017 |
| Targeting GNE Myopathy: A Dual Prodrug Approach for the Delivery of N-Acetylmannosamine 6-Phosphate C Morozzi, J Sedláková, M Serpi, M Avigliano, R Carbajo, L Sandoval, ... Journal of medicinal chemistry 62 (17), 8178-8193, 2019 | 17 | 2019 |
| Drug repurposing: phosphate prodrugs of anticancer and antiviral FDA-approved nucleosides as novel antimicrobials F Pertusati, E Pileggi, J Richards, M Wootton, T Van Leemputte, ... Journal of Antimicrobial Chemotherapy 75 (10), 2864-2878, 2020 | 16 | 2020 |
| Rational design and synthesis of novel anti-prostate cancer agents bearing a 3, 5-bis-trifluoromethylphenyl moiety S Ferla, M Bassetto, F Pertusati, S Kandil, AD Westwell, A Brancale, ... Bioorganic & medicinal chemistry letters 26 (15), 3636-3640, 2016 | 15 | 2016 |
