关注
Jing Huang
Jing Huang
National Cancer Institute, National Institutes of Health
在 mail.nih.gov 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
p53 is regulated by the lysine demethylase LSD1
J Huang, R Sengupta, AB Espejo, MG Lee, JA Dorsey, M Richter, ...
Nature 449 (7158), 105-108, 2007
9542007
Repression of p53 activity by Smyd2-mediated methylation
J Huang, L Perez-Burgos, BJ Placek, R Sengupta, M Richter, JA Dorsey, ...
Nature 444 (7119), 629-632, 2006
7552006
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
CHASLB Jiajun Zhu, Morgan A. Sammons, Greg Donahue, Zhixun Dou, Masoud ...
Nature, 2015
4972015
G9a and Glp methylate lysine 373 in the tumor suppressor p53
J Huang, J Dorsey, S Chuikov, X Zhang, T Jenuwein, D Reinberg, ...
Journal of Biological Chemistry 285 (13), 9636-9641, 2010
4612010
T cell stemness and dysfunction in tumors are triggered by a common mechanism
SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ...
Science 363 (6434), eaau0135, 2019
4322019
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes
J Yang, J Huang, M Dasgupta, N Sears, M Miyagi, B Wang, MR Chance, ...
Proceedings of the National Academy of Sciences 107 (50), 21499-21504, 2010
3612010
The emerging field of dynamic lysine methylation of non-histone proteins
J Huang, SL Berger
Current opinion in genetics & development 18 (2), 152-158, 2008
3412008
Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells
M Li, Y He, W Dubois, X Wu, J Shi, J Huang
Molecular cell, 2012
3122012
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression
E Shema, I Tirosh, Y Aylon, J Huang, C Ye, N Moskovits, N Raver-Shapira, ...
Genes & development 22 (19), 2664-2676, 2008
3102008
Single-chain estrogen receptors (ERs) reveal that the ERα/β heterodimer emulates functions of the ERα dimer in genomic estrogen signaling pathways
X Li, J Huang, P Yi, RA Bambara, R Hilf, M Muyan
Molecular and cellular biology, 2004
2312004
Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines
F Liu, D Barsyte-Lovejoy, A Allali-Hassani, Y He, JM Herold, X Chen, ...
Journal of medicinal chemistry 54 (17), 6139-6150, 2011
1672011
A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells
KH Lee, M Li, AM Michalowski, X Zhang, H Liao, L Chen, Y Xu, X Wu, ...
Proceedings of the National Academy of Sciences 107 (1), 69-74, 2010
1602010
The effects of estrogen-responsive element-and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ERα and ERβ
P Yi, MD Driscoll, J Huang, S Bhagat, R Hilf, RA Bambara, M Muyan
Molecular Endocrinology 16 (4), 674-693, 2002
1542002
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue
J Shi, CN Marconett, J Duan, PL Hyland, P Li, Z Wang, W Wheeler, ...
Nature communications 5 (1), 3365, 2014
1532014
Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1
J Huang, JR Kent, B Placek, KA Whelan, CM Hollow, PY Zeng, NW Fraser, ...
Journal of virology 80 (12), 5740-5746, 2006
1332006
The histone variant H3. 3 regulates gene expression during lytic infection with herpes simplex virus type 1
BJ Placek, J Huang, JR Kent, J Dorsey, L Rice, NW Fraser, SL Berger
Journal of virology 83 (3), 1416-1421, 2009
1252009
Direct regulation of alternative splicing by SMAD3 through PCBP1 is essential to the tumor-promoting role of TGF-β
V Tripathi, KM Sixt, S Gao, X Xu, J Huang, R Weigert, M Zhou, YE Zhang
Molecular cell 64 (3), 549-564, 2016
1002016
Current developments of targeting the p53 signaling pathway for cancer treatment
J Huang
Pharmacology & therapeutics 220, 107720, 2021
972021
An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells
M Li, H Gou, BK Tripathi, J Huang, S Jiang, W Dubois, T Waybright, M Lei, ...
Cell Stem Cell, 2015
942015
Targeting protein lysine methylation and demethylation in cancers
Y He, I Korboukh, J Jin, J Huang
Acta Biochim Biophys Sin 44 (1), 70-79, 2012
822012
系统目前无法执行此操作,请稍后再试。
文章 1–20