| Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases A Pierce, RD Unwin, CA Evans, S Griffiths, L Carney, L Zhang, ... Molecular & Cellular Proteomics 7 (5), 853-863, 2008 | 344 | 2008 |
| Systems-level dynamic analyses of fate change in murine embryonic stem cells R Lu, F Markowetz, RD Unwin, JT Leek, EM Airoldi, BD MacArthur, ... Nature 462 (7271), 358-362, 2009 | 334 | 2009 |
| Proteomic changes in renal cancer and co‐ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect RD Unwin, RA Craven, P Harnden, S Hanrahan, N Totty, M Knowles, ... PROTEOMICS: International Edition 3 (8), 1620-1632, 2003 | 288 | 2003 |
| Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS RD Unwin, JR Griffiths, AD Whetton Nature protocols 5 (9), 1574-1582, 2010 | 278 | 2010 |
| Multiple reaction monitoring to identify sites of protein phosphorylation with high sensitivity* S RD Unwin, JR Griffiths, MK Leverentz, A Grallert, IM Hagan, AD Whetton Molecular & cellular proteomics 4 (8), 1134-1144, 2005 | 263 | 2005 |
| Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells RD Unwin, DL Smith, D Blinco, CL Wilson, CJ Miller, CA Evans, ... Blood 107 (12), 4687-4694, 2006 | 212 | 2006 |
| Regional protein expression in human Alzheimer’s brain correlates with disease severity J Xu, S Patassini, N Rustogi, I Riba-Garcia, BD Hale, AM Phillips, ... Communications biology 2 (1), 43, 2019 | 166 | 2019 |
| Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder J Xu, P Begley, SJ Church, S Patassini, KA Hollywood, M Jüllig, MA Curtis, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (6 …, 2016 | 143 | 2016 |
| Quantitative Proteomic Analysis Using Isobaric Protein Tags Enables Rapid Comparison of Changes in Transcript and Protein Levels in Transformed Cells* S RD Unwin, A Pierce, RB Watson, DW Sternberg, AD Whetton Molecular & cellular proteomics 4 (7), 924-935, 2005 | 141 | 2005 |
| Serological and proteomic evaluation of antibody responses in the identification of tumor antigens in renal cell carcinoma RD Unwin, P Harnden, D Pappin, D Rahman, P Whelan, RA Craven, ... Proteomics 3 (1), 45-55, 2003 | 122 | 2003 |
| A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and … RD Unwin, JR Griffiths, AD Whetton Nature protocols 4 (6), 870-877, 2009 | 119 | 2009 |
| Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma RA Craven, AJ Stanley, S Hanrahan, J Dods, R Unwin, N Totty, ... Proteomics 6 (9), 2853-2864, 2006 | 107 | 2006 |
| Effects of obesity on perivascular adipose tissue vasorelaxant function: nitric oxide, inflammation and elevated systemic blood pressure R Aghamohammadzadeh, RD Unwin, AS Greenstein, AM Heagerty Journal of vascular research 52 (5), 299-305, 2016 | 100 | 2016 |
| Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy OJ Freeman, RD Unwin, AW Dowsey, P Begley, S Ali, KA Hollywood, ... Diabetes 65 (1), 228-238, 2016 | 100 | 2016 |
| Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera TDL Keenan, SJ Clark, RD Unwin, LA Ridge, AJ Day, PN Bishop Investigative ophthalmology & visual science 53 (12), 7528-7538, 2012 | 91 | 2012 |
| Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia J Xu, SJ Church, S Patassini, P Begley, HJ Waldvogel, MA Curtis, ... Metallomics 9 (8), 1106-1119, 2017 | 89 | 2017 |
| Quantification of proteins by iTRAQ RD Unwin LC-MS/MS in proteomics: methods and applications, 205-215, 2010 | 86 | 2010 |
| Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia J Xu, P Begley, SJ Church, S Patassini, S McHarg, N Kureishy, ... Scientific reports 6 (1), 27524, 2016 | 83 | 2016 |
| Relative quantification in proteomics: new approaches for biochemistry RD Unwin, CA Evans, AD Whetton Trends in biochemical sciences 31 (8), 473-484, 2006 | 83 | 2006 |
| Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer’s disease J Xu, S Patassini, P Begley, S Church, HJ Waldvogel, RLM Faull, ... Biochemical and biophysical research communications 527 (3), 676-681, 2020 | 82 | 2020 |
