Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma R Bonavia, A Mukasa, Y Narita, DWY Sah, S Vandenberg, C Brennan, ... Genes & development 24 (16), 1731-1745, 2010 | 600 | 2010 |
Targeting the ERBB family in cancer: couples therapy N Tebbutt, MW Pedersen, TG Johns Nature Reviews Cancer 13 (9), 663-673, 2013 | 504 | 2013 |
The epidermal growth factor receptor variant III (EGFR v III): where wild things are altered HK Gan, AN Cvrljevic, TG Johns The FEBS journal 280 (21), 5350-5370, 2013 | 428 | 2013 |
Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis CCA Bernard, TG Johns, A Slavin, M Ichikawa, C Ewing, J Liu, ... Journal of molecular medicine 75, 77-88, 1997 | 362 | 1997 |
The structure and function of myelin oligodendrocyte glycoprotein TG Johns, CCA Bernard Journal of neurochemistry 72 (1), 1-9, 1999 | 355 | 1999 |
A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors AM Scott, FT Lee, N Tebbutt, R Herbertson, SS Gill, Z Liu, E Skrinos, ... Proceedings of the National Academy of Sciences 104 (10), 4071-4076, 2007 | 306 | 2007 |
Targeted drug delivery using genetically engineered diatom biosilica B Delalat, VC Sheppard, S Rasi Ghaemi, S Rao, CA Prestidge, G McPhee, ... Nature communications 6 (1), 8791, 2015 | 295 | 2015 |
Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806 … K Mishima, TG Johns, RB Luwor, AM Scott, E Stockert, AA Jungbluth, ... Cancer research 61 (14), 5349-5354, 2001 | 265 | 2001 |
A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor AA Jungbluth, E Stockert, HJ Huang, VP Collins, K Coplan, K Iversen, ... Proceedings of the National Academy of Sciences 100 (2), 639, 2003 | 260 | 2003 |
Validation of the MTT dye assay for enumeration of cells in proliferative and antiproliferative assays. BE Loveland, TG Johns, IR Mackay, F Vaillant, ZX Wang, PJ Hertzog Biochemistry international 27 (3), 501-510, 1992 | 227 | 1992 |
Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2–7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR RB Luwor, TG Johns, C Murone, HJS Huang, WK Cavenee, G Ritter, ... Cancer research 61 (14), 5355-5361, 2001 | 220 | 2001 |
Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury B Liu, H Chen, TG Johns, AH Neufeld Journal of Neuroscience 26 (28), 7532-7540, 2006 | 213 | 2006 |
Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor TG Johns, TE Adams, JR Cochran, NE Hall, PA Hoyne, MJ Olsen, YS Kim, ... Journal of Biological Chemistry 279 (29), 30375-30384, 2004 | 184 | 2004 |
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients KV Lu, S Zhu, A Cvrljevic, TT Huang, S Sarkaria, D Ahkavan, J Dang, ... Cancer research 69 (17), 6889-6898, 2009 | 183 | 2009 |
Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon β TG Johns, IR Mackay, KA Callister, PJ Hertzog, RJ Devenish, ... JNCI: Journal of the National Cancer Institute 84 (15), 1185-1190, 1992 | 182 | 1992 |
Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis. TG Johns, N Kerlero de Rosbo, KK Menon, S Abo, MF Gonzales, ... Journal of immunology (Baltimore, Md.: 1950) 154 (10), 5536-5541, 1995 | 174 | 1995 |
Novel monoclonal antibody specific for the de2‐7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene TG Johns, E Stockert, G Ritter, AA Jungbluth, HJS Huang, WK Cavenee, ... International journal of cancer 98 (3), 398-408, 2002 | 170 | 2002 |
The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis CS Clements, HH Reid, T Beddoe, FE Tynan, MA Perugini, TG Johns, ... Proceedings of the National Academy of Sciences 100 (19), 11059-11064, 2003 | 164 | 2003 |
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma BW Stringer, BW Day, RCJ D’Souza, PR Jamieson, KS Ensbey, ZC Bruce, ... Scientific reports 9 (1), 4902, 2019 | 157 | 2019 |
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor–specific antibody generates enhanced … RM Perera, Y Narita, FB Furnari, HK Gan, C Murone, M Ahlkvist, ... Clinical Cancer Research 11 (17), 6390-6399, 2005 | 150 | 2005 |