Molecular hybridization: a useful tool in the design of new drug prototypes C Viegas-Junior, A Danuello, V da Silva Bolzani, EJ Barreiro, CAM Fraga Current medicinal chemistry 14 (17), 1829-1852, 2007 | 1209 | 2007 |
Os produtos naturais e a química medicinal moderna C Viegas Jr, VS Bolzani, EJ Barreiro Química nova 29, 326-337, 2006 | 461 | 2006 |
Terpenos com atividade inseticida: uma alternativa para o controle químico de insetos C Viegas Júnior Química Nova 26, 390-400, 2003 | 390 | 2003 |
Multi-target directed drugs: a modern approach for design of new drugs for the treatment of Alzheimer’s disease K Simone Tranches Dias, C Viegas Current Neuropharmacology 12 (3), 239-255, 2014 | 187 | 2014 |
Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer C Viegas Junior, VS Bolzani, M Furlan, CAM Fraga, EJ Barreiro Química Nova 27, 655-660, 2004 | 180 | 2004 |
The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, ... Molecules 17 (7), 7887-7902, 2012 | 175 | 2012 |
Further Bioactive Piperidine Alkaloids from the Flowers and Green Fruits of Cassia spectabilis C Viegas, V da S. Bolzani, M Furlan, EJ Barreiro, MCM Young, ... Journal of Natural Products 67 (5), 908-910, 2004 | 151 | 2004 |
Potential impact of the multi-target drug approach in the treatment of some complex diseases XH Makhoba, C Viegas Jr, RA Mosa, FPD Viegas, OJ Pooe Drug design, development and therapy, 3235-3249, 2020 | 145 | 2020 |
The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease M Divino da Rocha, F Pereira Dias Viegas, H Cristina Campos, ... CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2011 | 128 | 2011 |
Biological and chemical aspects of natural biflavonoids from plants: a brief review VS Gontijo, MH Dos Santos, C Viegas Jr Mini reviews in medicinal chemistry 17 (10), 834-862, 2017 | 101 | 2017 |
Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp VS Gontijo, TC de Souza, IA Rosa, MG Soares, MA da Silva, W Vilegas, ... Food chemistry 132 (3), 1230-1235, 2012 | 95 | 2012 |
The Keap1/Nrf2-ARE pathway as a pharmacological target for chalcones M de Freitas Silva, L Pruccoli, F Morroni, G Sita, F Seghetti, C Viegas Jr, ... Molecules 23 (7), 1803, 2018 | 93 | 2018 |
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids C Viegas Jr, VS Bolzani, LSB Pimentel, NG Castro, RF Cabral, RS Costa, ... Bioorganic & medicinal chemistry 13 (13), 4184-4190, 2005 | 87 | 2005 |
Multi-target directed drugs as a modern approach for drug design towards Alzheimer's disease: an update M de Freitas Silva, KST Dias, VS Gontijo, CJC Ortiz, C Viegas Jr Current Medicinal Chemistry 25 (29), 3491-3525, 2018 | 85 | 2018 |
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease KST Dias, CT de Paula, T Dos Santos, INO Souza, MS Boni, ... European journal of medicinal chemistry 130, 440-457, 2017 | 84 | 2017 |
Molecular hybridization as a tool in the design of multi-target directed drug candidates for neurodegenerative diseases VS Gontijo, FPD Viegas, CJC Ortiz, M de Freitas Silva, CM Damasio, ... Current neuropharmacology 18 (5), 348-407, 2020 | 81 | 2020 |
Plant derived alkaloid (−)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models KABS da Silva, MN Manjavachi, AF Paszcuk, M Pivatto, C Viegas Jr, ... Neuropharmacology 62 (2), 967-977, 2012 | 81 | 2012 |
Natural products from Brazilian biodiversity as a source of new models for medicinal chemistry VS Bolzani, M Valli, M Pivatto, C Viegas Jr Pure and Applied Chemistry 84 (9), 1837-1846, 2012 | 79 | 2012 |
Donepezil: an important prototype to the design of new drug candidates for Alzheimer’s disease M Cecilia Rodrigues Simoes, F Pereira Dias Viegas, M Soares Moreira, ... Mini reviews in medicinal chemistry 14 (1), 2-19, 2014 | 73 | 2014 |
New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors C Viegas Jr, VS Bolzani, EJ Barreiro, CA Manssour Fraga Mini Reviews in Medicinal Chemistry 5 (10), 915-926, 2005 | 70 | 2005 |