Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer D Cui Zhou, RG Jayasinghe, S Chen, JM Herndon, MD Iglesia, P Navale, ... Nature genetics 54 (9), 1390-1405, 2022 | 99 | 2022 |
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function VG D’Agostino, P Lal, B Mantelli, C Tiedje, C Zucal, N Thongon, ... Scientific reports 5 (1), 16478, 2015 | 82 | 2015 |
Regulation of HuR structure and function by dihydrotanshinone-I P Lal, L Cerofolini, VG D’Agostino, C Zucal, C Fuccio, I Bonomo, E Dassi, ... Nucleic acids research 45 (16), 9514-9527, 2017 | 76 | 2017 |
Targeting the multifaceted HuR protein, benefits and caveats C Zucal, V D’Agostino, R Loffredo, B Mantelli, N Thongon, P Lal, E Latorre, ... Current drug targets 16 (5), 499-515, 2015 | 76 | 2015 |
Interfering with HuR–RNA interaction: design, synthesis and biological characterization of tanshinone mimics as novel, effective HuR inhibitors L Manzoni, C Zucal, DD Maio, VG D’Agostino, N Thongon, I Bonomo, ... Journal of Medicinal Chemistry 61 (4), 1483-1498, 2018 | 48 | 2018 |
Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma Y Wu, NV Terekhanova, W Caravan, N Naser Al Deen, P Lal, S Chen, ... Nature communications 14 (1), 1681, 2023 | 16 | 2023 |
Spatial drivers and pre-cancer populations collaborate with the microenvironment in untreated and chemo-resistant pancreatic cancer DC Zhou, RG Jayasinghe, JM Herndon, E Storrs, CK Mo, Y Wu, RS Fulton, ... BioRxiv, 2021.01. 13.426413, 2021 | 13 | 2021 |
Aza-tanshinone derivatives, process for their preparation and their use in therapy A Provenzani, VG D'agostino, N Thongon, C Zucal, LAL Preet, V Adami, ... US Patent 10,689,342, 2020 | 1 | 2020 |
Isolation and Characterization of Bacteriocin Producing Lactic Acid Bacteria’s from Fermented Milk Products of Solan District of Himachal Pradesh A Pratush, A Gupta, I sha Mahajan, M Sharma, JK Rana, S Kumari Biological Forum—An International Journal 201 (3), 1, 2011 | 1* | 2011 |
Deciphering the roles of germline predisposition variants and somatic mutations on breast cancer cells and the tumor microenvironment FM Rodrigues, K Gallant, R Jayasinghe, M Iglesia, A Houston, S Chen, ... Cancer Research 84 (6_Supplement), 1773-1773, 2024 | | 2024 |
CRISPR-Mediated knockout of Ceruloplasmin (CP) and UCHL1 reveals angiogenic role in renal cell carcinoma (RCC) cell survival and proliferation W Caravan, Y Wu, P Lal, K Sato, Y Li, NNA Deen, S Chen, A Abedin, ... Cancer Research 84 (6_Supplement), 5670-5670, 2024 | | 2024 |
Establishing a papillary renal cell carcinoma mouse model with activating Met mutation P Lal, L Ding, F Chen Cancer Research 84 (6_Supplement), 1442-1442, 2024 | | 2024 |
Molecular signatures associated with the progression from DCIS to IDC S Chen, A Karpova, P Lal, E Storrs, R Jayasinghe, M Iglesia, A Houston, ... Cancer Research 84 (6_Supplement), 1157-1157, 2024 | | 2024 |
Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma Y Wu, S Chen, X Yang, K Sato, P Lal, Y Wang, AT Shinkle, MC Wendl, ... Cancer research 83 (24), 4161-4178, 2023 | | 2023 |
Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages MD Iglesia, RG Jayasinghe, S Chen, NV Terekhanova, JM Herndon, ... bioRxiv, 2023.10. 31.565031, 2023 | | 2023 |
Author Correction: Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma Y Wu, NV Terekhanova, W Caravan, N Naser Al Deen, P Lal, S Chen, ... nature communications 14 (1), 2817, 2023 | | 2023 |
Chromatin accessibility shapes tumor architecture and microenvironment in clear cell renal cell carcinoma Y Wu, N Terekhanova, W Caravan, A Karpova, S Cao, S Chen, H Zhu, ... | | 2022 |
Spatial transcriptomic profiling of progression markers in clear cell renal cell carcinoma CK Mo, Y Wu, T Nadezhda, C Wagma, P Lal, S Chen, NNAL Deen, R Liu, ... Cancer Research 82 (12_Supplement), 2025-2025, 2022 | | 2022 |
Spatial transcriptomics and multiplexed imaging to explore tumor heterogeneity and immune complexity S Chen, A Shinkle, Y Zhao, CK Mo, A Houston, P Lal, JM Herndon, ... Cancer Research 82 (12_Supplement), 1710-1710, 2022 | | 2022 |
Characterization of Small Molecules Inhibiting the RNA Binding Protein HuR P Lal University of Trento, 2017 | | 2017 |