Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy Y Alvarez, K Chen, AL Reynolds, N Waghorne, JJ O’Connor, BN Kennedy Disease models & mechanisms 3 (3-4), 236-245, 2010 | 132 | 2010 |
Selective inhibition of retinal angiogenesis by targeting PI3 kinase Y Alvarez, O Astudillo, L Jensen, AL Reynolds, N Waghorne, DP Brazil, ... PloS one 4 (11), e7867, 2009 | 90 | 2009 |
Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10) LCS Tam, AS Kiang, A Kennan, PF Kenna, N Chadderton, M Ader, A Palfi, ... Human molecular genetics 17 (14), 2084-2100, 2008 | 66 | 2008 |
In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1 I Fichtner, J Cinatl, M Michaelis, L C Sanders, R Hilger, B N Kennedy, ... Letters in Drug Design & Discovery 9 (9), 815-822, 2012 | 57 | 2012 |
A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model. C Daly, L Shine, T Heffernan, S Deeti, AL Reynolds, JJ O'Connor, ... Sci Rep. 7 (1), 11320., 2017 | 43 | 2017 |
Targeting the PI3K/Akt/mTOR pathway in ocular neovascularization T Sasore, AL Reynolds, BN Kennedy Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 805-811, 2014 | 42 | 2014 |
Phenotype-based discovery of 2-[(E)-2-(Quinolin-2-yl) vinyl] phenol as a novel regulator of ocular angiogenesis AL Reynolds, Y Alvarez, T Sasore, N Waghorne, CT Butler, C Kilty, ... Journal of Biological Chemistry 291 (14), 7242-7255, 2016 | 40 | 2016 |
Unexpected genetic heterogeneity for primary ciliary dyskinesia in the Irish Traveller population JP Casey, PA McGettigan, F Healy, C Hogg, A Reynolds, BN Kennedy, ... European Journal of Human Genetics 23 (2), 210-217, 2015 | 38 | 2015 |
A Sustained Release Formulation of Novel Quininib-Hyaluronan Microneedles Inhibits Angiogenesis and Retinal Vascular Permeability In Vivo. KBN Galvin OM, Srivastava A, Carroll O, Kulkarni R, Dykes S, Vickers S ... Journal of Controlled Release, 10.1016/j.jconrel.2016.04.004, 2016 | 36* | 2016 |
Brain-derived neurotrophic factor as a treatment option for retinal degeneration C Daly, R Ward, AL Reynolds, O Galvin, RF Collery, BN Kennedy Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 465-471, 2018 | 24 | 2018 |
A quininib analogue and cysteinyl leukotriene receptor antagonist inhibits vascular endothelial growth factor (VEGF)-independent angiogenesis and exerts an additive … CT Butler, AL Reynolds, M Tosetto, ET Dillon, PJ Guiry, G Cagney, ... Journal of Biological Chemistry 292 (9), 3552-3567, 2017 | 24 | 2017 |
Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer AG Murphy, R Casey, A Maguire, M Tosetto, CT Butler, E Conroy, ... Scientific reports 6 (1), 34523, 2016 | 24 | 2016 |
Inhibition of the Pim1 oncogene results in diminished visual function J Yin, L Shine, F Raycroft, S Deeti, A Reynolds, KM Ackerman, A Glaviano, ... PloS one 7 (12), e52177, 2012 | 24 | 2012 |
Curcumin sensitizes kidney cancer cells to TRAIL-induced apoptosis via ROS mediated activation of JNK-CHOP pathway and upregulation of DR4 I Obaidi, H Cassidy, V Ibanez Gaspar, J McCaul, M Higgins, M Halász, ... Biology 9 (5), 92, 2020 | 23 | 2020 |
Pyrazinib (P3),[(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma AM Buckley, MR Dunne, N Lynam-Lennon, SA Kennedy, A Cannon, ... Cancer letters 447, 115-129, 2019 | 22 | 2019 |
No evidence to support an association between the oestrogen receptor beta gene and bipolar disorder. MKP Kealey C, Reynolds A, Mynett-Johnson L, Claffey E Psychiatr Genet 11 (4), 223-6, 2001 | 20 | 2001 |
Pharmacological restoration of visual function in a zebrafish model of von-Hippel Lindau disease R Ward, Z Ali, K Slater, AL Reynolds, LD Jensen, BN Kennedy Developmental biology 457 (2), 226-234, 2020 | 14 | 2020 |
Emerging Drug Therapies for Inherited Retinal Dystrophies. KB Sundaramurthi H, Moran A, Perpetuini AC, Reynolds A Adv Exp Med Biol. 1185, 263-267, 2019 | 12* | 2019 |
The role of mitochondria in optic atrophy with autosomal inheritance EL Strachan, D Mac White-Begg, J Crean, AL Reynolds, BN Kennedy, ... Frontiers in Neuroscience 15, 784987, 2021 | 8 | 2021 |
On the importance of integrating comparative anatomy and One Health perspectives in anatomy education S Bhattacharjee, D Ceri Davies, JC Holland, JM Holmes, D Kilroy, ... Journal of Anatomy 240 (3), 429-446, 2022 | 7 | 2022 |