| Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ... Cell 172 (5), 979-992. e6, 2018 | 461 | 2018 |
| Development of a spontaneously active dorsal root ganglia assay using multiwell multielectrode arrays K Newberry, S Wang, N Hoque, L Kiss, MK Ahlijanian, J Herrington, ... Journal of neurophysiology 115 (6), 3217-3228, 2016 | 52 | 2016 |
| An acquired channelopathy involving thalamic T-type Ca2+ channels after status epilepticus JD Graef, BK Nordskog, WF Wiggins, DW Godwin Journal of Neuroscience 29 (14), 4430-4441, 2009 | 51 | 2009 |
| TC-8831, a nicotinic acetylcholine receptor agonist, reduces L-DOPA-induced dyskinesia in the MPTP macaque TH Johnston, P Huot, SH Fox, JB Koprich, KT Szeliga, JW James, ... Neuropharmacology 73, 337-347, 2013 | 49 | 2013 |
| Effect of acute NR2B antagonist treatment on long-term potentiation in the rat hippocampus JD Graef, K Newberry, A Newton, R Pieschl, E Shields, F Luan, ... Brain Research 1609, 31-39, 2015 | 42 | 2015 |
| Differential pharmacologies of mecamylamine enantiomers: positive allosteric modulation and noncompetitive inhibition NB Fedorov, LC Benson, J Graef, PM Lippiello, M Bencherif Journal of Pharmacology and Experimental Therapeutics 328 (2), 525-532, 2009 | 38 | 2009 |
| Development of New Benzenesulfonamides As Potent and Selective Nav1.7 Inhibitors for the Treatment of Pain YJ Wu, J Guernon, J Shi, J Ditta, KJ Robbins, R Rajamani, A Easton, ... Journal of Medicinal Chemistry 60 (6), 2513-2525, 2017 | 37 | 2017 |
| Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons JD Graef, H Wu, C Ng, C Sun, V Villegas, D Qadir, K Jesseman, ... European Journal of Neuroscience 51 (10), 2143-2157, 2020 | 32 | 2020 |
| Disrupted Thalamic T-Type Ca2+ Channel Expression and Function During Ethanol Exposure and Withdrawal JD Graef, TW Huitt, BK Nordskog, JH Hammarback, DW Godwin Journal of neurophysiology 105 (2), 528-540, 2011 | 26 | 2011 |
| Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain G Luo, L Chen, A Easton, A Newton, C Bourin, E Shields, K Mosure, ... Journal of Medicinal Chemistry 62 (2), 831-856, 2018 | 24 | 2018 |
| B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor DJ Post-Munson, RL Pieschl, TF Molski, JD Graef, AW Hendricson, ... European Journal of Pharmacology 799, 16-25, 2017 | 21 | 2017 |
| Preclinical characterization of (R)-3-((3S, 4S)-3-fluoro-4-(4-hydroxyphenyl) piperidin-1-yl)-1-(4-methylbenzyl) pyrrolidin-2-one (BMS-986169), a novel, intravenous, glutamate N … LJ Bristow, J Gulia, MR Weed, BN Srikumar, YW Li, JD Graef, PS Naidu, ... Journal of Pharmacology and Experimental Therapeutics 363 (3), 377-393, 2017 | 20 | 2017 |
| Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and nursery rearing GM Alexander, JD Graef, JA Hammarback, BK Nordskog, EJ Burnett, ... Neuroscience 207, 167-181, 2012 | 18 | 2012 |
| Validation of a high-throughput, automated electrophysiology platform for the screening of nicotinic agonists and antagonists JD Graef, LC Benson, SS Sidach, H Wei, PM Lippiello, M Bencherif, ... Journal of biomolecular screening 18 (1), 116-127, 2013 | 17 | 2013 |
| Ethosuximide Reduces Ethanol Withdrawal–Mediated Disruptions in Sleep‐Related EEG Patterns WF Wiggins, JD Graef, TW Huitt, DW Godwin Alcoholism: Clinical and Experimental Research 37 (3), 372-382, 2013 | 14 | 2013 |
| Intrinsic plasticity in acquired epilepsy: too much of a good thing? JD Graef, DW Godwin The Neuroscientist 16 (5), 487-495, 2010 | 11 | 2010 |
| A method for bidirectional solution exchange—“Liquid bullet” applications of acetylcholine to α7 nicotinic receptors N Fedorov, L Benson, JD Graef, J Hyman, J Sollenberger, F Pettersson, ... Journal of neuroscience methods 206 (1), 23-33, 2012 | 6 | 2012 |
| Slice XVIvo™: a novel electrophysiology system with the capability for 16 independent brain slice recordings JD Graef, H Wei, PM Lippiello, M Bencherif, N Fedorov Journal of Neuroscience Methods 212 (2), 228-233, 2013 | 5 | 2013 |
| AAV-based CRISPR-Cas9 genome editing: challenges and engineering opportunities AM Kabadi, MK Mejia-Guerra, JD Graef, SZ Khan, EM Walton, X Wang, ... Current Opinion in Biomedical Engineering, 100517, 2023 | 2 | 2023 |
| Antibodies to alpha-synuclein and uses thereof MK Ahlijanian, JE Meredith Jr, N Devidze, JD Graef, EL Halk US Patent 11,142,570, 2021 | 1 | 2021 |
