Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial RH Green, CE Brightling, S McKenna, B Hargadon, D Parker, P Bradding, ... The Lancet 360 (9347), 1715-1721, 2002 | 2198 | 2002 |
Mepolizumab and exacerbations of refractory eosinophilic asthma P Haldar, CE Brightling, B Hargadon, S Gupta, W Monteiro, A Sousa, ... New England journal of medicine 360 (10), 973-984, 2009 | 2163 | 2009 |
Mast-cell infiltration of airway smooth muscle in asthma CE Brightling, P Bradding, FA Symon, ST Holgate, AJ Wardlaw, ID Pavord New England Journal of Medicine 346 (22), 1699-1705, 2002 | 1596 | 2002 |
Interleukin-4,-5, and-6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. P Bradding, JA Roberts, KM Britten, S Montefort, R Djukanovic, R Mueller, ... American journal of respiratory cell and molecular biology 10 (5), 471-480, 1994 | 1096 | 1994 |
Evidence of a role of tumor necrosis factor α in refractory asthma MA Berry, B Hargadon, M Shelley, D Parker, DE Shaw, RH Green, ... New England Journal of Medicine 354 (7), 697-708, 2006 | 1082 | 2006 |
The role of the mast cell in the pathophysiology of asthma P Bradding, AF Walls, ST Holgate Journal of Allergy and Clinical Immunology 117 (6), 1277-1284, 2006 | 798 | 2006 |
Interleukin 4 is localized to and released by human mast cells. P Bradding, IH Feather, PH Howarth, R Mueller, JA Roberts, K Britten, ... The Journal of experimental medicine 176 (5), 1381-1386, 1992 | 776 | 1992 |
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients G Jia, RW Erickson, DF Choy, S Mosesova, LC Wu, OD Solberg, ... Journal of Allergy and Clinical Immunology 130 (3), 647-654. e10, 2012 | 742 | 2012 |
Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal … P Bradding, IH Feather, S Wilson, PG Bardin, CH Heusser, ST Holgate, ... Journal of immunology (Baltimore, Md.: 1950) 151 (7), 3853-3865, 1993 | 720 | 1993 |
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma M Berry, A Morgan, DE Shaw, D Parker, R Green, C Brightling, ... Thorax 62 (12), 1043-1049, 2007 | 635 | 2007 |
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma DF Choy, KM Hart, LA Borthwick, A Shikotra, DR Nagarkar, S Siddiqui, ... Science translational medicine 7 (301), 301ra129-301ra129, 2015 | 494 | 2015 |
Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease CE Brightling, S McKenna, B Hargadon, S Birring, R Green, R Siva, ... Thorax 60 (3), 193-198, 2005 | 449 | 2005 |
Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non–small-cell lung cancer TJ Welsh, RH Green, D Richardson, DA Waller, KJ O'Byrne, P Bradding Journal of clinical oncology 23 (35), 8959-8967, 2005 | 431 | 2005 |
Heterogeneity of human mast cells based on cytokine content. P Bradding, Y Okayama, PH Howarth, MK Church, ST Holgate Journal of immunology (Baltimore, Md.: 1950) 155 (1), 297-307, 1995 | 395 | 1995 |
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle CE Brightling, AJ Ammit, D Kaur, JL Black, AJ Wardlaw, JM Hughes, ... American journal of respiratory and critical care medicine 171 (10), 1103-1108, 2005 | 363 | 2005 |
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma A Shikotra, DF Choy, CM Ohri, E Doran, C Butler, B Hargadon, M Shelley, ... Journal of allergy and clinical immunology 129 (1), 104-111. e9, 2012 | 352 | 2012 |
Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy ST Holgate, P Bradding, AP Sampson, S is supported by the Frances, ... Journal of Allergy and Clinical Immunology 98 (1), 1-13, 1996 | 348 | 1996 |
Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival CM Ohri, A Shikotra, RH Green, DA Waller, P Bradding European Respiratory Journal 33 (1), 118-126, 2009 | 345 | 2009 |
Increased sputum and bronchial biopsy IL-13 expression in severe asthma SK Saha, MA Berry, D Parker, S Siddiqui, A Morgan, R May, P Monk, ... Journal of Allergy and Clinical Immunology 121 (3), 685-691, 2008 | 324 | 2008 |
Comparison of airway immunopathology of eosinophilic bronchitis and asthma CE Brightling, FA Symon, SS Birring, P Bradding, AJ Wardlaw, ID Pavord Thorax 58 (6), 528-532, 2003 | 321 | 2003 |