Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease D Sehlin, XT Fang, L Cato, G Antoni, L Lannfelt, S Syvänen Nature communications 7 (1), 10759, 2016 | 201 | 2016 |
Bivalent brain shuttle increases antibody uptake by monovalent binding to the transferrin receptor G Hultqvist, S Syvänen, XT Fang, L Lannfelt, D Sehlin Theranostics 7 (2), 308, 2017 | 168 | 2017 |
Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells XT Fang, D Sehlin, L Lannfelt, S Syvänen, G Hultqvist Biological procedures online 19, 1-9, 2017 | 93 | 2017 |
Gray and white matter degeneration revealed by diffusion in an Alzheimer mouse model V Zerbi, M Kleinnijenhuis, X Fang, D Jansen, A Veltien, J Van Asten, ... Neurobiology of aging 34 (5), 1440-1450, 2013 | 81 | 2013 |
Astroglial responses to amyloid-beta progression in a mouse model of Alzheimer’s disease M Olsen, X Aguilar, D Sehlin, XT Fang, G Antoni, A Erlandsson, ... Molecular Imaging and Biology 20, 605-614, 2018 | 77 | 2018 |
Multinutrient diets improve cerebral perfusion and neuroprotection in a murine model of Alzheimer's disease V Zerbi, D Jansen, M Wiesmann, X Fang, LM Broersen, A Veltien, ... Neurobiology of aging 35 (3), 600-613, 2014 | 72 | 2014 |
High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain XT Fang, G Hultqvist, SR Meier, G Antoni, D Sehlin, S Syvänen Neuroimage 184, 881-888, 2019 | 65 | 2019 |
A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils–a new concept for neuroimaging S Syvänen, XT Fang, G Hultqvist, SR Meier, L Lannfelt, D Sehlin Neuroimage 148, 55-63, 2017 | 61 | 2017 |
Antibody-based in vivo PET imaging detects amyloid-β reduction in Alzheimer transgenic mice after BACE-1 inhibition SR Meier, S Syvänen, G Hultqvist, XT Fang, S Roshanbin, L Lannfelt, ... Journal of Nuclear Medicine 59 (12), 1885-1891, 2018 | 53 | 2018 |
Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β D Sehlin, XT Fang, SR Meier, M Jansson, S Syvänen Scientific Reports 7 (1), 17254, 2017 | 53 | 2017 |
Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size R Faresjö, G Bonvicini, XT Fang, X Aguilar, D Sehlin, S Syvänen Fluids and Barriers of the CNS 18 (1), 26, 2021 | 49 | 2021 |
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q J Spurrier, LS Nicholson, XT Fang, AJ Stoner, T Toyonaga, D Holden, ... Science translational medicine 14 (647), eabi8593, 2022 | 48 | 2022 |
Effects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 mice D Jansen, V Zerbi, IAC Arnoldussen, M Wiesmann, A Rijpma, XT Fang, ... PloS one 8 (9), e75393, 2013 | 48 | 2013 |
Fluorine-18-labeled antibody ligands for PET imaging of amyloid-β in brain S Syvanen, XT Fang, R Faresjo, J Rokka, L Lannfelt, DE Olberg, ... ACS Chemical Neuroscience 11 (24), 4460-4468, 2020 | 36 | 2020 |
Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [11C] ABP688 PET imaging and ex vivo immunoblotting XT Fang, J Eriksson, G Antoni, U Yngve, L Cato, L Lannfelt, D Sehlin, ... Neuropharmacology 113, 293-300, 2017 | 34 | 2017 |
Sex differences in presynaptic density and neurogenesis in middle‐aged ApoE4 and ApoE knockout mice A Rijpma, D Jansen, IAC Arnoldussen, XT Fang, M Wiesmann, ... Journal of neurodegenerative diseases 2013 (1), 531326, 2013 | 31 | 2013 |
Quantification of SV2A Binding in Rodent Brain Using [18F]SynVesT-1 and PET Imaging P Sadasivam, XT Fang, T Toyonaga, S Lee, Y Xu, MQ Zheng, J Spurrier, ... Molecular imaging and biology 23, 372-381, 2021 | 23 | 2021 |
Identifying brain networks in synaptic density PET (11C-UCB-J) with independent component analysis XT Fang, T Toyonaga, AT Hillmer, D Matuskey, SE Holmes, ... Neuroimage 237, 118167, 2021 | 21 | 2021 |
Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and 11C-UCB-J PET study XT Fang, T Volpi, SE Holmes, I Esterlis, RE Carson, PD Worhunsky Frontiers in human neuroscience 17, 1124254, 2023 | 7 | 2023 |
ICA‐derived sources of synaptic density PET ([11C]UCB‐J) relate to cognitive impairment severity in Alzheimer’s disease: Neuroimaging: Imaging the human … XT Fang, AP Mecca, M Naganawa, RS O'Dell, MK Chen, CH van Dyck, ... Alzheimer's & Dementia 16, e041197, 2020 | 2 | 2020 |