Immune response in mice that lack the interferon-γ receptor S Huang, W Hendriks, A Althage, S Hemmi, H Bluethmann, R Kamijo, ... Science 259 (5102), 1742-1745, 1993 | 1988 | 1993 |
Biology of disease J Le, J Vilcek Tumor necrosis factor and interleukin 1, 234-248, 1987 | 1877 | 1987 |
Tumor necrosis factor: new insights into the molecular mechanisms of its multiple actions J Vilcek, TH Lee Journal of Biological Chemistry 266 (12), 7313-7316, 1991 | 1293 | 1991 |
Requirement for transcription factor IRF-1 in NO synthase induction in macrophages R Kamijo, H Harada, T Matsuyama, M Bosland, J Gerecitano, D Shapiro, ... Science 263 (5153), 1612-1615, 1994 | 1060 | 1994 |
Construction and initial characterization of a mouse-human chimeric anti-TNF antibody DM Knight, HAN Trinh, J Le, S Siegel, D Shealy, M McDonough, ... Molecular immunology 30 (16), 1443-1453, 1993 | 1001 | 1993 |
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. D Aderka, JM Le, J Vilcek Journal of immunology (Baltimore, Md.: 1950) 143 (11), 3517-3523, 1989 | 832 | 1989 |
Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors. J Vilcek, VJ Palombella, D Henriksen-DeStefano, C Swenson, R Feinman, ... The Journal of experimental medicine 163 (3), 632-643, 1986 | 803 | 1986 |
Induction of β2-interferon by tumor necrosis factor: a homeostatic mechanism in the control of cell proliferation M Kohase, D Henriksen-DeStefano, LT May, J Vilček, PB Sehgal Cell 45 (5), 659-666, 1986 | 735 | 1986 |
Interleukin 6: a multifunctional cytokine regulating immune reactions and the acute phase protein response J Le, J Vilček Pathology Reviews• 1990, 97-111, 1990 | 707 | 1990 |
Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells. M Tsujimoto, YK Yip, J Vilcek Proceedings of the National Academy of Sciences 82 (22), 7626-7630, 1985 | 595 | 1985 |
Production of high-titered interferon in cultures of human diploid cells EA Havell, J Vilček Antimicrobial agents and chemotherapy 2 (6), 476-484, 1972 | 589 | 1972 |
Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon OT Preble, RJ Black, RM Friedman, JH Klippel, J Vilček Science 216 (4544), 429-431, 1982 | 565 | 1982 |
Interferons and other cytokines J Vilcek Fields virology, 1996 | 466* | 1996 |
Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guérin and subsequent challenge with lipopolysaccharide. R Kamijo, J Le, D Shapiro, EA Havell, S Huang, M Aguet, M Bosland, ... The Journal of experimental medicine 178 (4), 1435-1440, 1993 | 451 | 1993 |
Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor. M Tsujimoto, YK Yip, J Vilcek Journal of immunology (Baltimore, Md.: 1950) 136 (7), 2441-2444, 1986 | 398 | 1986 |
A cytokine network in human diploid fibroblasts: interactions of β-interferons, tumor necrosis factor, platelet-derived growth factor, and interleukin-1 M Kohase, LT May, I Tamm, J Vilček, PB Sehgal Molecular and cellular biology, 1987 | 393 | 1987 |
Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies J Le, J Vilcek, P Dadonna, J Ghrayeb, D Knight, SA Siegel US Patent 5,656,272, 1997 | 391 | 1997 |
Acid-labile human leukocyte interferon in homosexual men with Kaposi's sarcoma and lymphadenopathy E DeStefano, RM Friedman, AE Friedman-Kien, JJ Goedert, D Henriksen, ... Journal of Infectious Diseases 146 (4), 451-455, 1982 | 391 | 1982 |
Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6. YH Zhang, JX Lin, YK Yip, J Vilcek Proceedings of the National Academy of Sciences 85 (18), 6802-6805, 1988 | 389 | 1988 |
Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways. T FuJITA, LF Reis, N Watanabe, Y KIMuRA, T Taniguchi, J Vilcek Proceedings of the National Academy of Sciences 86 (24), 9936-9940, 1989 | 378 | 1989 |