| Drug-induced liver injury in obesity and nonalcoholic fatty liver disease J Allard, D Le Guillou, K Begriche, B Fromenty Advances in Pharmacology 85, 75-107, 2019 | 93 | 2019 |
| A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: application to acetaminophen A Michaut, D Le Guillou, C Moreau, S Bucher, MR McGill, S Martinais, ... Toxicology and applied pharmacology 292, 40-55, 2016 | 80 | 2016 |
| Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo S Bucher, A Tête, N Podechard, M Liamin, D Le Guillou, M Chevanne, ... Scientific reports 8 (1), 5963, 2018 | 46 | 2018 |
| Relationships between radial glial progenitors and 5‐HT neurons in the paraventricular organ of adult zebrafish–potential effects of serotonin on adult neurogenesis MR Pérez, E Pellegrini, J Cano‐Nicolau, MM Gueguen, ... European Journal of Neuroscience 38 (9), 3292-3301, 2013 | 45 | 2013 |
| Possible involvement of mitochondrial dysfunction and oxidative stress in a cellular model of NAFLD progression induced by benzo [a] pyrene/ethanol coexposure S Bucher, D Le Guillou, J Allard, G Pinon, K Begriche, A Tête, O Sergent, ... Oxidative medicine and cellular longevity 2018 (1), 4396403, 2018 | 41 | 2018 |
| Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity J Allard, S Bucher, J Massart, PJ Ferron, D Le Guillou, R Loyant, Y Daniel, ... Cell Biology and Toxicology 37, 151-175, 2021 | 34 | 2021 |
| Drug-induced alterations of mitochondrial DNA homeostasis in steatotic and nonsteatotic HepaRG cells D Le Guillou, S Bucher, K Begriche, D Hoët, A Lombès, G Labbe, ... Journal of Pharmacology and Experimental Therapeutics 365 (3), 711-726, 2018 | 31 | 2018 |
| Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure S Bucher, P Jalili, D Le Guillou, K Begriche, K Rondel, S Martinais, ... Environmental toxicology 32 (3), 1024-1036, 2017 | 26 | 2017 |
| Induced pluripotent stem cell–derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile CC Duwaerts, D Le Guillou, CL Her, NJ Phillips, H Willenbring, AN Mattis, ... Gastroenterology 160 (7), 2591-2594. e6, 2021 | 17 | 2021 |
| Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice S Anthérieu, D Le Guillou, C Coulouarn, K Begriche, V Trak-Smayra, ... Toxicology and applied pharmacology 276 (1), 63-72, 2014 | 17 | 2014 |
| Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis S Sharma, D Le Guillou, JY Chen Nature Reviews Gastroenterology & Hepatology 20 (10), 662-678, 2023 | 14 | 2023 |
| Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate‐treated hepatocyte and stellate cell W Dornas, D Glaise, A Bodin, A Sharanek, A Burban, D Le Guillou, ... Journal of cellular physiology 234 (1), 122-133, 2019 | 6 | 2019 |
| Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages M Groeger, K Matsuo, E Heidary Arash, A Pereira, D Le Guillou, C Pino, ... Nature communications 14 (1), 3902, 2023 | 5 | 2023 |
| The role of STING in liver injury is both stimulus-and time-dependent K Siao, D Le Guillou, JJ Maher, CC Duwaerts Nutrients 14 (19), 4029, 2022 | 2 | 2022 |
| Benzo [a] pyrene and ethanol exert a high toxicity potential in steatotic HepaRG cells: possible role of low NDUFA4L2 expression S Bucher, D Le Guillou, K Begriche, C Coulouarn, B Fromenty Journal of Hepatology 1 (66), S402, 2017 | 1 | 2017 |
| COMPARATIVE ANALYSIS OF iPSC-DERIVED HEPATOCYTES (iPSC-HEPS) FROM NAFLD PATIENTS AND HEALTHY CONTROLS REVEALS IMPAIRED MITOCHONDRIAL FUNCTION IN NAFLD iPSC-HEPS D Le Guillou, CS Her, K Siao, SK Dhillon, CC Duwaerts, JJ Maher HEPATOLOGY 78, S1078-S1079, 2023 | | 2023 |
| The Role of STING in Liver Injury Is Both Stimulus-and Time-Dependent. Nutrients 2022, 14, 4029 K Siao, D Le Guillou, JJ Maher, CC Duwaerts s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022 | | 2022 |
| INDUCED PLURIPOTENT STEM CELL-DERIVED HEPATOCYTES (iPSC-HEPS) FROM PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE EXHIBIT IMPAIRED MITOCHONDRIAL FUNCTION COMPARED TO CONTROL … D Le Guillou, CL Her, K Siao, CC Duwaerts, JJ Maher HEPATOLOGY 74, 1072A-1072A, 2021 | | 2021 |
| Effets d’une co-exposition chronique au benzo [a] pyrène et à l’éthanol sur l’évolution de la NAFLD dans un modèle in vitro S Bucher Rennes 1, 2018 | | 2018 |
| Altérations de l'homéostasie de l'ADN mitochondrial par les médicaments et modulation par la stéatose hépatique| Theses. fr D Le Guillou Rennes 1, 2017 | | 2017 |
Simon BUCHER在 univ-rennes1.fr 的电子邮件经过验证
