A family of cAMP-binding proteins that directly activate Rap1 H Kawasaki, GM Springett, N Mochizuki, S Toki, M Nakaya, M Matsuda, ... Science 282 (5397), 2275-2279, 1998 | 1734 | 1998 |
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 T Kawai, S Sato, KJ Ishii, C Coban, H Hemmi, M Yamamoto, K Terai, ... Nature immunology 5 (10), 1061-1068, 2004 | 1318 | 2004 |
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells RE Itoh, K Kurokawa, Y Ohba, H Yoshizaki, N Mochizuki, M Matsuda Molecular and cellular biology, 2002 | 721 | 2002 |
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1 N Mochizuki, S Yamashita, K Kurokawa, Y Ohba, T Nagai, A Miyawaki, ... Nature 411 (6841), 1065-1068, 2001 | 716 | 2001 |
Development of an optimized backbone of FRET biosensors for kinases and GTPases N Komatsu, K Aoki, M Yamada, H Yukinaga, Y Fujita, Y Kamioka, ... Molecular biology of the cell 22 (23), 4647-4656, 2011 | 682 | 2011 |
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR) 7-and TLR9-mediated interferon-α induction S Uematsu, S Sato, M Yamamoto, T Hirotani, H Kato, F Takeshita, ... The Journal of experimental medicine 201 (6), 915-923, 2005 | 625 | 2005 |
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling E Hirata, MR Girotti, A Viros, S Hooper, B Spencer-Dene, M Matsuda, ... Cancer cell 27 (4), 574-588, 2015 | 602 | 2015 |
Binding of Transforming Protein, P47gag-crk, to a Broad Range of Phosphotyrosine-containing Proteins M Matsuda, BJ Mayer, Y Fukui, H Hanafusa Science 248 (4962), 1537-1539, 1990 | 551 | 1990 |
Activation of Rac1 by a Crk SH3-binding protein, DOCK180 E Kiyokawa, Y Hashimoto, S Kobayashi, H Sugimura, T Kurata, ... Genes & development 12 (21), 3331-3336, 1998 | 548 | 1998 |
C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins. S Tanaka, T Morishita, Y Hashimoto, S Hattori, S Nakamura, M Shibuya, ... Proceedings of the National Academy of Sciences 91 (8), 3443-3447, 1994 | 493 | 1994 |
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes H Yoshizaki, Y Ohba, K Kurokawa, RE Itoh, T Nakamura, N Mochizuki, ... The Journal of cell biology 162 (2), 223-232, 2003 | 483 | 2003 |
Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G T Gotoh, S Hattori, S Nakamura, H Kitayama, M Noda, Y Takai, K Kaibuchi, ... Molecular and cellular biology, 1995 | 457 | 1995 |
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia H Kawasaki, GM Springett, S Toki, JJ Canales, P Harlan, JP Blumenstiel, ... Proceedings of the National Academy of Sciences 95 (22), 13278-13283, 1998 | 443 | 1998 |
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane H Hasegawa, E Kiyokawa, S Tanaka, K Nagashima, N Gotoh, M Shibuya, ... Molecular and cellular biology 16 (4), 1770-1776, 1996 | 430 | 1996 |
Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes A Fujioka, K Terai, RE Itoh, K Aoki, T Nakamura, S Kuroda, E Nishida, ... Journal of biological chemistry 281 (13), 8917-8926, 2006 | 423 | 2006 |
Two Species of Human CRK cDNA Encode Proteins with Distinct Biological Activities M Matsuda, S Tanaka, S Nagata, A Kojima, T Kurata, M Shibuya Molecular and cellular biology 12 (8), 3482-3489, 1992 | 353 | 1992 |
Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation K Aoki, Y Kumagai, A Sakurai, N Komatsu, Y Fujita, C Shionyu, ... Molecular cell 52 (4), 529-540, 2013 | 335 | 2013 |
Roles played by a subset of integrin signaling molecules in cadherin-based cell–cell adhesion H Yano, Y Mazaki, K Kurokawa, SK Hanks, M Matsuda, H Sabe The Journal of cell biology 166 (2), 283-295, 2004 | 322 | 2004 |
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with Gαi N Mochizuki, Y Ohba, E Kiyokawa, T Kurata, T Murakami, T Ozaki, ... Nature 400 (6747), 891-894, 1999 | 313 | 1999 |
Evidence that DOCK180 up-regulates signals from the CrkII-p130Cas complex E Kiyokawa, Y Hashimoto, T Kurata, H Sugimura, M Matsuda Journal of Biological Chemistry 273 (38), 24479-24484, 1998 | 276 | 1998 |