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Aleša Bricelj
Aleša Bricelj
University of Ljubljana, Faculty of Pharmacy
在 ffa.uni-lj.si 的电子邮件经过验证
标题
引用次数
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年份
E3 ligase ligands in successful PROTACs: an overview of syntheses and linker attachment points
A Bricelj, C Steinebach, R Kuchta, M Gütschow, I Sosič
Frontiers in chemistry 9, 707317, 2021
1282021
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders
C Steinebach, YLD Ng, I Sosič, CS Lee, S Chen, S Lindner, LP Vu, ...
Chemical science 11 (13), 3474-3486, 2020
1012020
E3 ligase ligand chemistries: from building blocks to protein degraders
I Sosič, A Bricelj, C Steinebach
Chemical Society Reviews 51 (9), 3487-3534, 2022
662022
A MedChem toolbox for cereblon-directed PROTACs
C Steinebach, I Sosič, S Lindner, A Bricelj, F Kohl, YLD Ng, M Monschke, ...
MedChemComm 10 (6), 1037-1041, 2019
562019
Influence of linker attachment points on the stability and neosubstrate degradation of cereblon ligands
A Bricelj, YL Dora Ng, D Ferber, R Kuchta, S Müller, M Monschke, ...
ACS Medicinal Chemistry Letters 12 (11), 1733-1738, 2021
362021
A facile synthesis of ligands for the von Hippel–Lindau E3 ligase
C Steinebach, SA Voell, LP Vu, A Bricelj, I Sosič, G Schnakenburg, ...
Synthesis 52 (17), 2521-2527, 2020
242020
Medication review service implementation in community pharmacy settings: scoping review with focus on implementation studies
J Brandt, ML Lê, S Jantscher, A Bricelj, C Louizos, S Ng, K Sibley
Research in Social and Administrative Pharmacy 16 (7), 875-885, 2020
162020
Leveraging ligand affinity and properties: discovery of novel benzamide-type cereblon binders for the design of PROTACs
C Steinebach, A Bricelj, A Murgai, I Sosic, L Bischof, YLD Ng, C Heim, ...
Journal of medicinal chemistry 66 (21), 14513-14543, 2023
62023
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel–Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α …
LP Vu, CJ Diehl, R Casement, AG Bond, C Steinebach, N Strasek, ...
Journal of Medicinal Chemistry 66 (18), 12776-12811, 2023
22023
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor …
LP Vu, C Diehl, R Casement, A Bond, C Steinebach, N Strasek, A Bricelj, ...
12023
Heterobifunctional ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins
YLD Ng, A Bricelj, JA Jansen, A Murgai, K Peter, KA Donovan, ...
Journal of medicinal chemistry 66 (7), 4703-4733, 2023
12023
Design, synthesis, and evaluation of BCL‐2 targeting PROTACs
A Bricelj, YLD Ng, M Gobec, R Kuchta, W Hu, Š Javornik, M Rožič, ...
Chemistry–A European Journal, e202400430, 2024
2024
Načrtovanje, sinteza in vrednotenje himernih molekul za inducirano razgradnjo proteinov, vpletenih v patogenezo malignih obolenj
A Bricelj
Univerza v Ljubljani, Fakulteta za farmacijo, 2023
2023
PROTACS as tools for the modulation of pharmacological targets
I Sosic, C Steinebach, A Bricelj, YLD Ng, M Gobec, J Kroenke, RJ Pieters, ...
FEBS OPEN BIO 11, 100-100, 2021
2021
PROTAC-MEDIATED INACTIVATION OF E3 LIGASES: FROM TOOLS TO CANCER TREATMENT
C Steinebach, YLD Ng, A Bricelj, I Sosič, J Krönke, M Gütschow
Book of, 290, 0
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