Rotational resonance in solid state NMR DP Raleigh, MH Levitt, RG Griffin Chemical Physics Letters 146 (1-2), 71-76, 1988 | 700 | 1988 |
Theory and simulations of homonuclear spin pair systems in rotating solids MH Levitt, DP Raleigh, F Creuzet, RG Griffin The Journal of chemical physics 92 (11), 6347-6364, 1990 | 514 | 1990 |
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction B Fierz, C Chatterjee, RK McGinty, M Bar-Dagan, DP Raleigh, TW Muir Nature chemical biology 7 (2), 113-119, 2011 | 499 | 2011 |
De Novo Design of Helical Bundles as Models for Understanding Protein Folding and Function RB Hill, DP Raleigh, A Lombardi, WF DeGrado Accounts of chemical research 33 (11), 745-754, 2000 | 399 | 2000 |
Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution SH Shim, R Gupta, YL Ling, DB Strasfeld, DP Raleigh, MT Zanni Proceedings of the National Academy of Sciences 106 (16), 6614-6619, 2009 | 323 | 2009 |
The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP … F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh Biochemistry 49 (37), 8127-8133, 2010 | 307 | 2010 |
Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry LM Young, JC Saunders, RA Mahood, CH Revill, RJ Foster, LH Tu, ... Nature chemistry 7 (1), 73-81, 2015 | 293 | 2015 |
Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet LE Buchanan, EB Dunkelberger, HQ Tran, PN Cheng, CC Chiu, P Cao, ... Proceedings of the National Academy of Sciences 110 (48), 19285-19290, 2013 | 284 | 2013 |
Rational modification of protein stability by the mutation of charged surface residues S Spector, M Wang, SA Carp, J Robblee, ZS Hendsch, R Fairman, B Tidor, ... Biochemistry 39 (5), 872-879, 2000 | 265 | 2000 |
Protein folding: defining a “standard” set of experimental conditions and a preliminary kinetic data set of two‐state proteins KL Maxwell, D Wildes, A Zarrine‐Afsar, MA De Los Rios, AG Brown, ... Protein Science 14 (3), 602-616, 2005 | 259 | 2005 |
Islet amyloid polypeptide: structure, function, and pathophysiology R Akter, P Cao, H Noor, Z Ridgway, LH Tu, H Wang, AG Wong, X Zhang, ... Journal of diabetes research 2016 (1), 2798269, 2016 | 251 | 2016 |
Effects of sequential proline substitutions on amyloid formation by human amylin20-29 DF Moriarty, DP Raleigh Biochemistry 38 (6), 1811-1818, 1999 | 249 | 1999 |
De novo protein design: from molten globules to native-like states: Current opinion in structural biology 1993, 3: 601–610 SF Betz, DP Raleigh, WF DeGrado Current opinion in structural biology 3 (4), 601-610, 1993 | 244 | 1993 |
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence? S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ... Diabetologia 53, 1046-1056, 2010 | 231 | 2010 |
A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides A Abedini, DP Raleigh Protein Engineering, Design & Selection 22 (8), 453-459, 2009 | 219 | 2009 |
A role for helical intermediates in amyloid formation by natively unfolded polypeptides? A Abedini, DP Raleigh Physical biology 6 (1), 015005, 2009 | 211 | 2009 |
Ion mobility spectrometry–mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitors LM Young, P Cao, DP Raleigh, AE Ashcroft, SE Radford Journal of the American Chemical Society 136 (2), 660-670, 2014 | 208 | 2014 |
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ... Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010 | 204 | 2010 |
Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity P Cao, P Marek, H Noor, V Patsalo, LH Tu, H Wang, A Abedini, ... FEBS letters 587 (8), 1106-1118, 2013 | 199 | 2013 |
Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor CT Middleton, P Marek, P Cao, C Chiu, S Singh, AM Woys, JJ De Pablo, ... Nature chemistry 4 (5), 355-360, 2012 | 197 | 2012 |