| Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells D Balboa, T Barsby, V Lithovius, J Saarimäki-Vire, M Omar-Hmeadi, ... Nature biotechnology 40 (7), 1042-1055, 2022 | 207 | 2022 |
| Conditionally stabilized dCas9 activator for controlling gene expression in human cell reprogramming and differentiation D Balboa, J Weltner, S Eurola, R Trokovic, K Wartiovaara, T Otonkoski Stem cell reports 5 (3), 448-459, 2015 | 199 | 2015 |
| Human pluripotent reprogramming with CRISPR activators J Weltner, D Balboa, S Katayama, M Bespalov, K Krjutškov, EM Jouhilahti, ... Nature communications 9 (1), 2643, 2018 | 171 | 2018 |
| Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes D Balboa, J Saarimäki-Vire, D Borshagovski, M Survila, P Lindholm, ... Elife 7, e38519, 2018 | 145 | 2018 |
| An activating STAT3 mutation causes neonatal diabetes through premature induction of pancreatic differentiation J Saarimäki-Vire, D Balboa, MA Russell, J Saarikettu, M Kinnunen, ... Cell reports 19 (2), 281-294, 2017 | 112 | 2017 |
| Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes C Cosentino, S Toivonen, E Diaz Villamil, M Atta, JL Ravanat, S Demine, ... Nucleic acids research 46 (19), 10302-10318, 2018 | 111 | 2018 |
| Activin A and Wnt-dependent specification of human definitive endoderm cells S Toivonen, K Lundin, D Balboa, J Ustinov, K Tamminen, J Palgi, ... Experimental cell research 319 (17), 2535-2544, 2013 | 93 | 2013 |
| A strong contractile actin fence and large adhesions direct human pluripotent colony morphology and adhesion E Närvä, A Stubb, C Guzmán, M Blomqvist, D Balboa, M Lerche, M Saari, ... Stem cell reports 9 (1), 67-76, 2017 | 79 | 2017 |
| Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy HM Haikala, JM Anttila, E Marques, T Raatikainen, M Ilander, H Hakanen, ... Nature communications 10 (1), 620, 2019 | 71 | 2019 |
| Concise review: human pluripotent stem cells for the modeling of pancreatic β-cell pathology D Balboa, J Saarimäki-Vire, T Otonkoski Stem Cells 37 (1), 33-41, 2019 | 63 | 2019 |
| Loss of MANF causes childhood-onset syndromic diabetes due to increased endoplasmic reticulum stress H Montaser, KA Patel, D Balboa, H Ibrahim, V Lithovius, A Näätänen, ... Diabetes 70 (4), 1006-1018, 2021 | 40 | 2021 |
| Intestinal commitment and maturation of human pluripotent stem cells is independent of exogenous FGF4 and R-spondin1 K Tamminen, D Balboa, S Toivonen, MP Pakarinen, Z Wiener, K Alitalo, ... PLoS One 10 (7), e0134551, 2015 | 38 | 2015 |
| Human pluripotent stem cells to model islet defects in diabetes D Balboa, DG Iworima, TJ Kieffer Frontiers in Endocrinology 12, 642152, 2021 | 36 | 2021 |
| Genome editing of human pancreatic beta cell models: problems, possibilities and outlook D Balboa, RB Prasad, L Groop, T Otonkoski Diabetologia 62, 1329-1336, 2019 | 35 | 2019 |
| Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem–like Cells J Högström, S Heino, P Kallio, M Lähde, VM Leppänen, D Balboa, ... Cancer Research 78 (20), 5820-5832, 2018 | 31 | 2018 |
| Human pluripotent stem cell based islet models for diabetes research D Balboa, T Otonkoski Best Practice & Research Clinical Endocrinology & Metabolism 29 (6), 899-909, 2015 | 31 | 2015 |
| SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism V Lithovius, J Saarimäki-Vire, D Balboa, H Ibrahim, H Montaser, T Barsby, ... Diabetologia 64, 630-640, 2021 | 29 | 2021 |
| Redox regulation of GRPEL2 nucleotide exchange factor for mitochondrial HSP70 chaperone S Konovalova, X Liu, P Manjunath, S Baral, N Neupane, T Hilander, ... Redox biology 19, 37-45, 2018 | 29 | 2018 |
| The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α V Chandra, H Ibrahim, C Halliez, RB Prasad, F Vecchio, OP Dwivedi, ... Nature Communications 13 (1), 6363, 2022 | 27 | 2022 |
| Selective microRNA-Offset RNA expression in human embryonic stem cells S Asikainen, L Heikkinen, J Juhila, F Holm, J Weltner, R Trokovic, ... PLoS One 10 (3), e0116668, 2015 | 26 | 2015 |
Hazem IbrahimDoctoral Researcher, University of Helsinki在 helsinki.fi 的电子邮件经过验证
