| Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy S Maddika, SR Ande, S Panigrahi, T Paranjothy, K Weglarczyk, A Zuse, ... Drug Resistance Updates 10 (1-2), 13-29, 2007 | 599 | 2007 |
| WWP2 is an E3 ubiquitin ligase for PTEN S Maddika, S Kavela, N Rani, VR Palicharla, JL Pokorny, JN Sarkaria, ... Nature cell biology 13 (6), 728-733, 2011 | 362 | 2011 |
| Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development MV Jain, AM Paczulla, T Klonisch, FN Dimgba, SB Rao, K Roberg, ... Journal of cellular and molecular medicine 17 (1), 12-29, 2013 | 326 | 2013 |
| Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis S Maddika, SR Ande, E Wiechec, LL Hansen, S Wesselborg, M Los Journal of cell science 121 (7), 979-988, 2008 | 219 | 2008 |
| Switching Akt: from survival signaling to deadly response M Los, S Maddika, B Erb, K Schulze‐Osthoff Bioessays 31 (5), 492-495, 2009 | 203 | 2009 |
| Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase S Maddika, J Chen Nature cell biology 11 (4), 409-419, 2009 | 196 | 2009 |
| Deubiquitylation and stabilization of PTEN by USP13 J Zhang, P Zhang, Y Wei, H Piao, W Wang, S Maddika, M Wang, D Chen, ... Nature cell biology 15 (12), 1486-1494, 2013 | 195 | 2013 |
| Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy K Barczyk, M Kreuter, J Pryjma, EP Booy, S Maddika, S Ghavami, ... International journal of cancer 116 (2), 167-173, 2005 | 170 | 2005 |
| Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells RS Kuna, SB Girada, S Asalla, J Vallentyne, S Maddika, JT Patterson, ... American journal of physiology-endocrinology and metabolism 305 (2), E161-E170, 2013 | 160 | 2013 |
| PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7 SR Shinde, S Maddika Nature communications 7 (1), 10689, 2016 | 154 | 2016 |
| Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death … S Maddika, EP Booy, D Johar, SB Gibson, S Ghavami, M Los Journal of cell science 118 (19), 4485-4493, 2005 | 146 | 2005 |
| Cancer-selective therapy of the future: apoptin and its mechanism of action S Maddika, FJ Mendoza, K Hauff, CR Zamzow, T Paranjothy, M Los Cancer biology & therapy 5 (1), 10-19, 2006 | 129 | 2006 |
| Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent M Burek, S Maddika, CJ Burek, PT Daniel, K Schulze-Osthoff, M Los Oncogene 25 (15), 2213-2222, 2006 | 115 | 2006 |
| Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity S Maddika, S Panigrahi, E Wiechec, S Wesselborg, U Fischer, ... Molecular and cellular biology, 2009 | 89 | 2009 |
| Role of BNIP3 in TNF-induced cell death—TNF upregulates BNIP3 expression S Ghavami, M Eshraghi, K Kadkhoda, MM Mutawe, S Maddika, GH Bay, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (3), 546-560, 2009 | 81 | 2009 |
| HACE1 mediated K27 ubiquitin linkage leads to YB-1 protein secretion VR Palicharla, S Maddika Cellular Signalling 27 (12), 2355-2362, 2015 | 73 | 2015 |
| WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 … NR Gangula, S Maddika Journal of Biological Chemistry 288 (48), 34545-34554, 2013 | 73 | 2013 |
| Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor‐positive and‐negative human breast cancer cells via the intrinsic pathway M Hashemi, F Karami‐Tehrani, S Ghavami, S Maddika, M Los Cell proliferation 38 (5), 269-285, 2005 | 71 | 2005 |
| Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin‐induced cell death S Maddika, GH Bay, TJ Kroczak, SR Ande, S Maddika, E Wiechec, ... Cell proliferation 40 (6), 835-848, 2007 | 67 | 2007 |
| Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties B Dulla, KT Kirla, V Rathore, GS Deora, S Kavela, S Maddika, K Chatti, ... Organic & biomolecular chemistry 11 (19), 3103-3107, 2013 | 66 | 2013 |
