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Zhiren Wang
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年份
Vitamin A inhibits the action of LPS on the intestinal epithelial barrier function and tight junction proteins
C He, J Deng, X Hu, S Zhou, J Wu, D Xiao, KO Darko, Y Huang, T Tao, ...
Food & function 10 (2), 1235-1242, 2019
1452019
Design, synthesis, and evaluation of orally available clioquinol-moracin M hybrids as multitarget-directed ligands for cognitive improvement in a rat model of neurodegeneration …
Z Wang, Y Wang, B Wang, W Li, L Huang, X Li
Journal of Medicinal Chemistry 58 (21), 8616-8637, 2015
1202015
Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer’s disease
Z Wang, Y Wang, W Li, F Mao, Y Sun, L Huang, X Li
ACS chemical neuroscience 5 (10), 952-962, 2014
1042014
Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy
Z Wang, N Little, J Chen, KT Lambesis, KT Le, W Han, AJ Scott, J Lu
Nature nanotechnology 16 (10), 1130-1140, 2021
972021
Design, synthesis, and evaluation of orally bioavailable quinoline–indole derivatives as innovative multitarget-directed ligands: Promotion of cell proliferation in the adult …
Z Wang, J Hu, X Yang, X Feng, X Li, L Huang, ASC Chan
Journal of Medicinal Chemistry 61 (5), 1871-1894, 2018
862018
Novel application of metformin combined with targeted drugs on anticancer treatment
J Deng, M Peng, Z Wang, S Zhou, D Xiao, J Deng, X Yang, J Peng, ...
Cancer science 110 (1), 23-30, 2019
572019
Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer’s disease
S Xie, J Chen, X Li, T Su, Y Wang, Z Wang, L Huang, X Li
Bioorganic & Medicinal Chemistry 23 (13), 3722-3729, 2015
572015
Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery
Z Wang, J Chen, N Little, J Lu
Acta biomaterialia 111, 20-28, 2020
412020
Design, synthesis and evaluation of clioquinol–ebselen hybrids as multi-target-directed ligands against Alzheimer's disease
Z Wang, W Li, Y Wang, X Li, L Huang, X Li
RSC advances 6 (9), 7139-7158, 2016
262016
Camptothesome elicits immunogenic cell death to boost colorectal cancer immune checkpoint blockade
Z Wang, W Li, J Park, KM Gonzalez, AJ Scott, J Lu
Journal of Controlled Release 349, 929-939, 2022
252022
Hybrids consisting of the pharmacophores of salmeterol and roflumilast or phthalazinone: dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of COPD
A Liu, L Huang, Z Wang, Z Luo, F Mao, W Shan, J Xie, K Lai, X Li
Bioorganic & medicinal chemistry letters 23 (5), 1548-1552, 2013
242013
Computer-assisted designed “selenoxy–chinolin”: a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation
Z Wang, Y Wang, W Li, Z Liu, Z Luo, Y Sun, R Wu, L Huang, X Li
Dalton Transactions 44 (48), 20913-20925, 2015
192015
Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives
D Xiao, Z Lu, Z Wang, S Zhou, M Cao, J Deng, X Hu, M Peng, C He, J Wu, ...
Bioorganic & Medicinal Chemistry 28 (2), 115258, 2020
142020
Anticancer properties of novel pyrazole‐containing biguanide derivatives with activating the adenosine monophosphate‐activated protein kinase signaling pathway
S Zhou, L Xu, M Cao, Z Wang, D Xiao, S Xu, J Deng, X Hu, C He, T Tao, ...
Archiv Der Pharmazie 352 (9), 1900075, 2019
142019
Synthesis and evaluation of 8-hydroxyquinolin derivatives substituted with (benzo [d][1, 2] selenazol-3 (2H)-one) as effective inhibitor of metal-induced Aβ aggregation and …
B Wang, Z Wang, H Chen, CJ Lu, X Li
Bioorganic & Medicinal Chemistry 24 (19), 4741-4749, 2016
142016
WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP …
Z Wang, M Cao, H Xiang, W Wang, X Feng, X Yang
ACS Chemical Neuroscience 10 (12), 4787-4799, 2019
82019
Lipid-Based Nanotechnology: Liposome
Y Jiang, W Li, Z Wang, J Lu
Pharmaceutics 16 (1), 34, 2023
72023
Camptothesome potentiates PD-L1 immune checkpoint blockade for improved metastatic triple-negative breast cancer Immunochemotherapy
Z Wang, LE Cordova, P Chalasani, J Lu
Molecular pharmaceutics 19 (12), 4665-4674, 2022
62022
Synthesis, anti-proliferative evaluation and mechanism of 4-trifluoro methoxy proguanil derivatives with various carbon chain length
S Xu, Y Cao, Y Luo, D Xiao, W Wang, Z Wang, X Yang
Molecules 26 (19), 5775, 2021
62021
Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy
Z Wang, W Li, Y Jiang, TB Tran, LE Cordova, J Chung, M Kim, G Wondrak, ...
Nature Communications 14 (1), 7235, 2023
22023
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