| PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication J Bianchi, SG Rudd, SK Jozwiakowski, LJ Bailey, V Soura, E Taylor, ... Molecular cell 52 (4), 566-573, 2013 | 301 | 2013 |
| Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 142 | 2016 |
| Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies N Herold, SG Rudd, L Ljungblad, K Sanjiv, IH Myrberg, CBJ Paulin, ... Nature medicine 23 (2), 256, 2017 | 128 | 2017 |
| Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism N Tsesmetzis, C Paulin, S Rudd, N Herold Cancers 10 (7), 240, 2018 | 121 | 2018 |
| Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins TA Guilliam, SK Jozwiakowski, A Ehlinger, RP Barnes, SG Rudd, ... Nucleic acids research 43 (2), 1056-1068, 2015 | 120 | 2015 |
| Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells BDG Page, NCK Valerie, RHG Wright, O Wallner, R Isaksson, M Carter, ... Nature communications 9 (1), 250, 2018 | 77 | 2018 |
| SAMHD1 protects cancer cells from various nucleoside-based antimetabolites N Herold, SG Rudd, K Sanjiv, J Kutzner, J Bladh, CBJ Paulin, T Helleday, ... Cell Cycle 16 (11), 1029-1038, 2017 | 69 | 2017 |
| PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African Trypanosome SG Rudd, L Glover, SK Jozwiakowski, D Horn, AJ Doherty Molecular cell 52 (4), 554-565, 2013 | 69 | 2013 |
| Pathways controlling dNTP pools to maintain genome stability SG Rudd, NCK Valerie, T Helleday DNA repair 44, 193-204, 2016 | 64 | 2016 |
| With me or against me: Tumor suppressor and drug resistance activities of SAMHD1 N Herold, SG Rudd, K Sanjiv, J Kutzner, IH Myrberg, CBJ Paulin, ... Experimental hematology 52, 32-39, 2017 | 52 | 2017 |
| PrimPol—A new polymerase on the block SG Rudd, J Bianchi, AJ Doherty Molecular & Cellular Oncology 1 (2), e960754, 2014 | 52 | 2014 |
| Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy SG Rudd, N Tsesmetzis, K Sanjiv, CBJ Paulin, L Sandhow, J Kutzner, ... EMBO Molecular Medicine, 2020 | 47 | 2020 |
| WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line SJ Goodfellow, MR Rebello, E Toska, LAH Zeef, SG Rudd, KF Medler, ... Biochemical Journal 435 (1), 113-125, 2011 | 47 | 2011 |
| Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens GZ Rassidakis, N Herold, IH Myrberg, N Tsesmetzis, SG Rudd, JI Henter, ... Blood cancer journal 8 (11), 98, 2018 | 37 | 2018 |
| Cell Cycle Profiling Reveals Protein Oscillation, Phosphorylation, and Localization Dynamics P Herr, J Boström, E Rullman, SG Rudd, M Vesterlund, J Lehtiö, ... Molecular & Cellular Proteomics 19 (4), 608-623, 2020 | 33 | 2020 |
| hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia S Eshtad, Z Mavajian, SG Rudd, T Visnes, J Boström, M Altun, T Helleday Oncogenesis 5 (12), e275-e275, 2016 | 22 | 2016 |
| MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells K Sanjiv, SG Rudd, O Mortusewicz, A Stolz, N Amaral, L Brautigham, ... Cancer Research 79 (13 Supplement), 105-105, 2019 | 21* | 2019 |
| MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells H Gad, O Mortusewicz, SG Rudd, A Stolz, N Amaral, L Brautigham, ... BioRxiv, 575290, 2019 | 21 | 2019 |
| MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG SG Rudd, H Gad, K Sanjiv, N Amaral, A Hagenkort, P Groth, CE Ström, ... Cancer research 80 (17), 3530-3541, 2020 | 19 | 2020 |
| Targeting the DNA damage response and repair in cancer through nucleotide metabolism T Helleday, SG Rudd Molecular Oncology 16 (21), 3792-3810, 2022 | 18 | 2022 |
