Origins of specificity and affinity in antibody–protein interactions HP Peng, KH Lee, JW Jian, AS Yang Proceedings of the National Academy of Sciences 111 (26), E2656-E2665, 2014 | 219 | 2014 |
Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: analysis of sentinel physician surveillance data FC Tseng, HC Huang, CY Chi, TL Lin, CC Liu, JW Jian, LC Hsu, HS Wu, ... Journal of medical virology 79 (12), 1850-1860, 2007 | 194 | 2007 |
Germline breast cancer susceptibility gene mutations and breast cancer outcomes YA Wang, JW Jian, CF Hung, HP Peng, CF Yang, HCS Cheng, AS Yang BMC cancer 18, 1-13, 2018 | 107 | 2018 |
Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface CM Yu, HP Peng, IC Chen, YC Lee, JB Chen, KC Tsai, CT Chen, ... PLoS One 7 (3), e33340, 2012 | 63 | 2012 |
Loop-sequence features and stability determinants in antibody variable domains by high-throughput experiments HJ Chang, JW Jian, HJ Hsu, YC Lee, HS Chen, JJ You, SC Hou, CY Shao, ... Structure 22 (1), 9-21, 2014 | 41 | 2014 |
Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces CT Chen, HP Peng, JW Jian, KC Tsai, JY Chang, EW Yang, JB Chen, ... PloS one 7 (6), e37706, 2012 | 37 | 2012 |
Genetic and epidemiological analysis of influenza virus epidemics in Taiwan during 2003 to 2006 JW Jian, GW Chen, CT Lai, LC Hsu, PJ Chen, SHS Kuo, HS Wu, SR Shih Journal of clinical microbiology 46 (4), 1426-1434, 2008 | 33 | 2008 |
Prediction of carbohydrate binding sites on protein surfaces with 3-dimensional probability density distributions of interacting atoms KC Tsai, JW Jian, EW Yang, PC Hsu, HP Peng, CT Chen, JB Chen, ... PLoS One 7 (7), e40846, 2012 | 31 | 2012 |
Genetic analysis and evaluation of the reassortment of influenza B viruses isolated in Taiwan during the 2004–2005 and 2006–2007 epidemics JW Jian, CT Lai, CY Kuo, SHS Kuo, LC Hsu, PJ Chen, HS Wu, MT Liu Virus research 131 (2), 243-249, 2008 | 31 | 2008 |
Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments HJ Hsu, KH Lee, JW Jian, HJ Chang, CM Yu, YC Lee, C Chen, HP Peng, ... Structure 22 (1), 22-34, 2014 | 30 | 2014 |
Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries CP Tung, IC Chen, CM Yu, HP Peng, JW Jian, SH Ma, YC Lee, JT Jan, ... Scientific Reports 5 (1), 15053, 2015 | 21 | 2015 |
Evaluating BRCA mutation risk predictive models in a Chinese cohort in Taiwan FH Hung, YA Wang, JW Jian, HP Peng, LL Hsieh, CF Hung, MM Yang, ... Scientific Reports 9 (1), 10229, 2019 | 18 | 2019 |
Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens HS Chen, SC Hou, JW Jian, KS Goh, ST Shen, YC Lee, JJ You, HP Peng, ... Scientific reports 5 (1), 12411, 2015 | 18 | 2015 |
Predicting ligand binding sites on protein surfaces by 3-dimensional probability density distributions of interacting atoms JW Jian, P Elumalai, T Pitti, CY Wu, KC Tsai, JY Chang, HP Peng, ... PloS one 11 (8), e0160315, 2016 | 17 | 2016 |
Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities JW Jian, HS Chen, YK Chiu, HP Peng, CP Tung, IC Chen, CM Yu, ... MAbs 11 (2), 373-387, 2019 | 15 | 2019 |
Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models WY Kuo, HJ Hsu, CY Wu, HS Chen, YC Chou, YL Tsou, HP Peng, ... MAbs 11 (1), 153-165, 2019 | 10 | 2019 |
One-step-one-pot hydrothermally derived metal-organic-framework-nanohybrids for integrated point-of-care diagnostics of SARS-CoV-2 viral antigen/pseudovirus utilizing … S Palanisamy, LY Lee, CF Kao, WL Chen, HC Wang, ST Shen, JW Jian, ... Sensors and Actuators B: Chemical 390, 133960, 2023 | 9 | 2023 |
Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries HJ Hsu, CP Tung, CM Yu, CY Chen, HS Chen, YC Huang, PH Tsai, SI Lin, ... Scientific Reports 11 (1), 15430, 2021 | 9 | 2021 |
A panel of anti-influenza virus nucleoprotein antibodies selected from phage-displayed synthetic antibody libraries with rapid diagnostic capability to distinguish diverse … CM Yu, IC Chen, CP Tung, HP Peng, JW Jian, YK Chiu, YL Tsou, ... Scientific Reports 10 (1), 13318, 2020 | 8 | 2020 |
Computational method for predicting functional sites of biological molecules AS Yang, HP Peng, JW Jian US Patent App. 14/215,163, 2014 | 1 | 2014 |