mRNA vaccines—a new era in vaccinology N Pardi, MJ Hogan, FW Porter, D Weissman Nature reviews Drug discovery 17 (4), 261-279, 2018 | 3798 | 2018 |
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination N Pardi, MJ Hogan, RS Pelc, H Muramatsu, H Andersen, CR DeMaso, ... Nature 543 (7644), 248-251, 2017 | 899 | 2017 |
Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes N Pardi, S Tuyishime, H Muramatsu, K Kariko, BL Mui, YK Tam, ... Journal of Controlled Release 217, 345-351, 2015 | 834 | 2015 |
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses N Pardi, MJ Hogan, MS Naradikian, K Parkhouse, DW Cain, L Jones, ... Journal of Experimental Medicine 215 (6), 1571-1588, 2018 | 458 | 2018 |
Recent advances in mRNA vaccine technology N Pardi, MJ Hogan, D Weissman Current opinion in immunology 65, 14-20, 2020 | 414 | 2020 |
D614G spike mutation increases SARS CoV-2 susceptibility to neutralization D Weissman, MG Alameh, T de Silva, P Collini, H Hornsby, R Brown, ... Cell host & microbe 29 (1), 23-31. e4, 2021 | 363 | 2021 |
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses MG Alameh, I Tombácz, E Bettini, K Lederer, S Ndeupen, C Sittplangkoon, ... Immunity 54 (12), 2877-2892. e7, 2021 | 342 | 2021 |
SARS-CoV-2 mRNA vaccines foster potent antigen-specific germinal center responses associated with neutralizing antibody generation K Lederer, D Castaño, DG Atria, TH Oguin, S Wang, TB Manzoni, ... Immunity 53 (6), 1281-1295. e5, 2020 | 339 | 2020 |
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge N Pardi, AJ Secreto, X Shan, F Debonera, J Glover, Y Yi, H Muramatsu, ... Nature communications 8 (1), 14630, 2017 | 328 | 2017 |
A single immunization with nucleoside-modified mRNA vaccines elicits strong cellular and humoral immune responses against SARS-CoV-2 in mice D Laczkó, MJ Hogan, SA Toulmin, P Hicks, K Lederer, BT Gaudette, ... Immunity 53 (4), 724-732. e7, 2020 | 325 | 2020 |
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels T Rothgangl, MK Dennis, PJC Lin, R Oka, D Witzigmann, L Villiger, W Qi, ... Nature biotechnology 39 (8), 949-957, 2021 | 239 | 2021 |
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies N Pardi, K Parkhouse, E Kirkpatrick, M McMahon, SJ Zost, BL Mui, ... Nature communications 9 (1), 3361, 2018 | 239 | 2018 |
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses KO Saunders, E Lee, R Parks, DR Martinez, D Li, H Chen, RJ Edwards, ... Nature 594 (7864), 553-559, 2021 | 227 | 2021 |
A multi-targeting, nucleoside-modified mRNA influenza virus vaccine provides broad protection in mice AW Freyn, JR da Silva, VC Rosado, CM Bliss, M Pine, BL Mui, YK Tam, ... Molecular Therapy 28 (7), 1569-1584, 2020 | 214 | 2020 |
In vitro transcription of long RNA containing modified nucleosides N Pardi, H Muramatsu, D Weissman, K Karikó Synthetic Messenger RNA and Cell Metabolism Modulation: Methods and …, 2013 | 183 | 2013 |
The transcription factor T-bet resolves memory B cell subsets with distinct tissue distributions and antibody specificities in mice and humans JL Johnson, RL Rosenthal, JJ Knox, A Myles, MS Naradikian, J Madej, ... Immunity 52 (5), 842-855. e6, 2020 | 175 | 2020 |
HPLC purification of in vitro transcribed long RNA D Weissman, N Pardi, H Muramatsu, K Karikó Synthetic messenger RNA and cell metabolism modulation: Methods and …, 2013 | 168 | 2013 |
mRNA vaccines in the COVID-19 pandemic and beyond MJ Hogan, N Pardi Annual review of medicine 73, 17-39, 2022 | 167 | 2022 |
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice DR Martinez, A Schäfer, SR Leist, G De la Cruz, A West, ... Science 373 (6558), 991-998, 2021 | 160 | 2021 |
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes CP Arevalo, MJ Bolton, V Le Sage, N Ye, C Furey, H Muramatsu, ... Science 378 (6622), 899-904, 2022 | 151 | 2022 |