Upregulation of sodium channel Nav1. 3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury BC Hains, JP Klein, CY Saab, MJ Craner, JA Black, SG Waxman Journal of Neuroscience 23 (26), 8881-8892, 2003 | 488 | 2003 |
Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury BC Hains, CY Saab, JP Klein, MJ Craner, SG Waxman Journal of Neuroscience 24 (20), 4832-4839, 2004 | 353 | 2004 |
Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities KD Davis, N Aghaeepour, AH Ahn, MS Angst, D Borsook, A Brenton, ... Nature Reviews Neurology 16 (7), 381-400, 2020 | 351 | 2020 |
Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo AC Lo, CY Saab, JA Black, SG Waxman Journal of neurophysiology 90 (5), 3566-3571, 2003 | 214 | 2003 |
Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury BC Hains, CY Saab, SG Waxman Brain 128 (10), 2359-2371, 2005 | 207 | 2005 |
The cerebellum: organization, functions and its role in nociception CY Saab, WD Willis Brain research reviews 42 (1), 85-95, 2003 | 197 | 2003 |
Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE JA Black, S Liu, BC Hains, CY Saab, SG Waxman Brain 129 (12), 3196-3208, 2006 | 135 | 2006 |
Pain-related changes in the brain: diagnostic and therapeutic potentials CY Saab Trends in neurosciences 35 (10), 629-637, 2012 | 120 | 2012 |
Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI BC Hains, CY Saab, AC Lo, SG Waxman Experimental neurology 188 (2), 365-377, 2004 | 120 | 2004 |
Preemptive intrathecal ketamine injection produces a long-lasting decrease in neuropathic pain behaviors in a rat model AW Burton, DH Lee, C Saab, JM Chung Regional anesthesia and pain medicine 24 (3), 208-213, 1999 | 113 | 1999 |
Alterations in Burst Firing of Thalamic VPL Neurons and Reversal by Nav1.3 Antisense After Spinal Cord Injury BC Hains, CY Saab, SG Waxman Journal of neurophysiology 95 (6), 3343-3352, 2006 | 107 | 2006 |
Neutrophils invade lumbar dorsal root ganglia after chronic constriction injury of the sciatic nerve N Morin, SA Owolabi, MW Harty, EF Papa, TF Tracy Jr, SK Shaw, M Kim, ... Journal of neuroimmunology 184 (1-2), 164-171, 2007 | 105 | 2007 |
Cortical theta is increased while thalamocortical coherence is decreased in rat models of acute and chronic pain BW LeBlanc, TR Lii, AE Silverman, RT Alleyne, CY Saab PAIN® 155 (4), 773-782, 2014 | 96 | 2014 |
Unilateral focal burn injury is followed by long-lasting bilateral allodynia and neuronal hyperexcitability in spinal cord dorsal horn YW Chang, A Tan, C Saab, S Waxman The Journal of Pain 11 (2), 119-130, 2010 | 91 | 2010 |
Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn SA Owolabi, CY Saab FEBS letters 580 (18), 4306-4310, 2006 | 89 | 2006 |
High-frequency stimulation in the ventral posterolateral thalamus reverses electrophysiologic changes and hyperalgesia in a rat model of peripheral neuropathic pain M Iwata, BW LeBlanc, LM Kadasi, ML Zerah, RG Cosgrove, CY Saab Pain 152 (11), 2505-2513, 2011 | 72 | 2011 |
Minocycline injection in the ventral posterolateral thalamus reverses microglial reactivity and thermal hyperalgesia secondary to sciatic neuropathy BW LeBlanc, ML Zerah, LM Kadasi, N Chai, CY Saab Neuroscience letters 498 (2), 138-142, 2011 | 69 | 2011 |
T-type calcium channel blocker Z944 restores cortical synchrony and thalamocortical connectivity in a rat model of neuropathic pain BW LeBlanc, TR Lii, JJ Huang, YC Chao, PM Bowary, BS Cross, MS Lee, ... Pain 157 (1), 255-263, 2016 | 68 | 2016 |
Microglia: a newly discovered role in visceral hypersensitivity? CY Saab, J Wang, C Gu, KN Garner, ED Al-Chaer Neuron glia biology 2 (4), 271-277, 2006 | 66 | 2006 |
Electroencephalographic signatures of pain and analgesia in rats BW LeBlanc, PM Bowary, YC Chao, TR Lii, CY Saab Pain 157 (10), 2330-2340, 2016 | 63 | 2016 |