| Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion F Rodier, JP Coppé, CK Patil, WAM Hoeijmakers, DP Muñoz, SR Raza, ... Nature cell biology 11 (8), 973-979, 2009 | 2296 | 2009 |
| Inflammatory networks during cellular senescence: causes and consequences A Freund, AV Orjalo, PY Desprez, J Campisi Trends in molecular medicine 16 (5), 238-246, 2010 | 1519 | 2010 |
| p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype A Freund, CK Patil, J Campisi The EMBO journal 30 (8), 1536-1548, 2011 | 1083 | 2011 |
| MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 1026 | 2015 |
| Mitochondrial dysfunction induces senescence with a distinct secretory phenotype CD Wiley, MC Velarde, P Lecot, SU Liu, EA Sarnoski, A Freund, ... Cell metabolism 23 (2), 303-314, 2016 | 1008 | 2016 |
| Lamin B1 loss is a senescence-associated biomarker A Freund, RM Laberge, M Demaria, J Campisi Molecular biology of the cell 23 (11), 2066-2075, 2012 | 956 | 2012 |
| Tumor suppressor and aging biomarker p16INK4a induces cellular senescence without the associated inflammatory secretory phenotype JP Coppé, F Rodier, CK Patil, A Freund, PY Desprez, J Campisi Journal of Biological Chemistry 286 (42), 36396-36403, 2011 | 523 | 2011 |
| Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells H Mou, V Vinarsky, PR Tata, K Brazauskas, SH Choi, AK Crooke, B Zhang, ... Cell stem cell 19 (2), 217-231, 2016 | 377 | 2016 |
| TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends FL Zhong, LFZ Batista, A Freund, MF Pech, AS Venteicher, SE Artandi Cell 150 (3), 481-494, 2012 | 359 | 2012 |
| Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype RM Laberge, L Zhou, MR Sarantos, F Rodier, A Freund, PLJ de Keizer, ... Aging cell 11 (4), 569-578, 2012 | 243 | 2012 |
| Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1 A Freund, FL Zhong, AS Venteicher, Z Meng, TD Veenstra, J Frydman, ... Cell 159 (6), 1389-1403, 2014 | 162 | 2014 |
| Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lopez, M Kawahara, ... JCI insight 4 (14), 2019 | 124 | 2019 |
| An activity switch in human telomerase based on RNA conformation and shaped by TCAB1 L Chen, CM Roake, A Freund, PJ Batista, S Tian, YA Yin, CR Gajera, ... Cell 174 (1), 218-230. e13, 2018 | 87 | 2018 |
| ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 56 | 2020 |
| Novel insights from a multiomics dissection of the Hayflick limit M Chan, H Yuan, I Soifer, TM Maile, RY Wang, A Ireland, JJ O'Brien, ... Elife 11, e70283, 2022 | 49 | 2022 |
| Untangling aging using dynamic, organism-level phenotypic networks A Freund Cell systems 8 (3), 172-181, 2019 | 31 | 2019 |
| Age and diet shape the genetic architecture of body weight in diversity outbred mice KM Wright, AG Deighan, A Di Francesco, A Freund, V Jojic, GA Churchill, ... Elife 11, e64329, 2022 | 14 | 2022 |
| Automated, high-dimensional evaluation of physiological aging and resilience in outbred mice Z Chen, A Raj, GV Prateek, A Di Francesco, J Liu, BE Keyes, G Kolumam, ... Elife 11, e72664, 2022 | 13 | 2022 |
| Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells M Mohrin, J Liu, J Zavala‐Solorio, S Bhargava, J Maxwell Trumble, A Brito, ... Aging Cell 20 (3), e13313, 2021 | 10 | 2021 |
| Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice G Zhang, A Deighan, A Raj, L Robinson, HJ Donato, G Garland, M Leland, ... Genetics 220 (1), iyab157, 2022 | 7 | 2022 |
Francis RodierUniversité de Montréal - Dep. Radiologie, radio-oncologie et médecine nucléaire - CHUM - CRCHUM在 umontreal.ca 的电子邮件经过验证
