Circulating microRNAs as stable blood-based markers for cancer detection PS Mitchell, RK Parkin, EM Kroh, BR Fritz, SK Wyman, ... Proceedings of the national academy of sciences 105 (30), 10513-10518, 2008 | 9942 | 2008 |
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma JD Arroyo, JR Chevillet, EM Kroh, IK Ruf, CC Pritchard, DF Gibson, ... Proceedings of the National Academy of Sciences 108 (12), 5003-5008, 2011 | 3904 | 2011 |
Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR) EM Kroh, RK Parkin, PS Mitchell, M Tewari Methods 50 (4), 298-301, 2010 | 1395 | 2010 |
MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries M Bar, SK Wyman, BR Fritz, J Qi, KS Garg, RK Parkin, EM Kroh, ... Stem cells 26 (10), 2496-2505, 2008 | 415 | 2008 |
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes A Sandstrom, PS Mitchell, L Goers, EW Mu, CF Lesser, RE Vance Science 364 (6435), eaau1330, 2019 | 352 | 2019 |
Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer WM Grady, RK Parkin, PS Mitchell, JH Lee, YH Kim, KD Tsuchiya, ... Oncogene 27 (27), 3880-3888, 2008 | 351 | 2008 |
Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries SK Wyman, RK Parkin, PS Mitchell, BR Fritz, K O'Briant, AK Godwin, ... PloS one 4 (4), e5311, 2009 | 297 | 2009 |
Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia HH Cheng, PS Mitchell, EM Kroh, AE Dowell, L Chéry, J Siddiqui, ... PloS one 8 (7), e69239, 2013 | 197 | 2013 |
The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries PS Mitchell, A Sandstrom, RE Vance Current opinion in immunology 60, 37-45, 2019 | 169 | 2019 |
MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression Y Wang, JW Huang, M Li, WK Cavenee, PS Mitchell, X Zhou, M Tewari, ... Molecular Cancer Research 9 (8), 1100-1111, 2011 | 169 | 2011 |
Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA PS Mitchell, C Patzina, M Emerman, O Haller, HS Malik, G Kochs Cell host & microbe 12 (4), 598-604, 2012 | 161 | 2012 |
Multiple integrated copies and high-level production of the human retrovirus XMRV (xenotropic murine leukemia virus-related virus) from 22Rv1 prostate carcinoma cells EC Knouf, MJ Metzger, PS Mitchell, JD Arroyo, JR Chevillet, M Tewari, ... Journal of virology 83 (14), 7353-7356, 2009 | 155 | 2009 |
Diverse viral proteases activate the NLRP1 inflammasome BV Tsu, C Beierschmitt, AP Ryan, R Agarwal, PS Mitchell, MD Daugherty elife 10, e60609, 2021 | 153 | 2021 |
Functional and evolutionary analyses identify proteolysis as a general mechanism for NLRP1 inflammasome activation J Chavarría-Smith, PS Mitchell, AM Ho, MD Daugherty, RE Vance PLoS pathogens 12 (12), e1006052, 2016 | 133 | 2016 |
Can Uhear me now? Validation of an iPod-based hearing loss screening test J Szudek, A Ostevik, P Dziegielewski, J Robinson-Anagor, N Gomaa, ... Journal of Otolaryngology-Head and Neck Surgery 41 (1), S78, 2012 | 131 | 2012 |
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity JW Huang, Y Wang, KK Dhillon, P Calses, E Villegas, PS Mitchell, ... Molecular cancer research 11 (12), 1564-1573, 2013 | 114 | 2013 |
MiR‐221 and MiR‐222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival K Wurz, RL Garcia, BA Goff, PS Mitchell, JH Lee, M Tewari, EM Swisher Genes, chromosomes and cancer 49 (7), 577-584, 2010 | 93 | 2010 |
A phase II trial to evaluate the efficacy of fostamatinib in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) IW Flinn, NL Bartlett, KA Blum, KM Ardeshna, AS LaCasce, CR Flowers, ... European journal of cancer 54, 11-17, 2016 | 86 | 2016 |
An evolutionary perspective on the broad antiviral specificity of MxA PS Mitchell, M Emerman, HS Malik Current opinion in microbiology 16 (4), 493-499, 2013 | 86 | 2013 |
NAIP–NLRC4-deficient mice are susceptible to shigellosis PS Mitchell, JL Roncaioli, EA Turcotte, L Goers, RA Chavez, AY Lee, ... Elife 9, e59022, 2020 | 85 | 2020 |