EMT, MET, plasticity, and tumor metastasis B Bakir, AM Chiarella, JR Pitarresi, AK Rustgi Trends in cell biology 30 (10), 764-776, 2020 | 679 | 2020 |
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer TA Mace, R Shakya, JR Pitarresi, B Swanson, CW McQuinn, S Loftus, ... Gut, gutjnl-2016-311585, 2016 | 464 | 2016 |
The ETS family of oncogenic transcription factors in solid tumours GM Sizemore, JR Pitarresi, S Balakrishnan, MC Ostrowski Nature Reviews Cancer 17 (6), 337, 2017 | 313 | 2017 |
Regulation of epithelial plasticity determines metastatic organotropism in pancreatic cancer M Reichert, B Bakir, L Moreira, JR Pitarresi, K Feldmann, L Simon, ... Developmental Cell 45 (6), 696-711. e8, 2018 | 127 | 2018 |
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration V Giroux, AA Lento, M Islam, JR Pitarresi, A Kharbanda, KE Hamilton, ... The Journal of clinical investigation 127 (6), 2378-2391, 2017 | 102 | 2017 |
IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-κB AR Victor, AP Nalin, W Dong, S McClory, M Wei, C Mao, RD Kladney, ... The Journal of Immunology 199 (7), 2333-2342, 2017 | 82 | 2017 |
Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis R Gogada, M Amadori, H Zhang, A Jones, A Verone, J Pitarresi, ... Cell Cycle 10 (23), 4128-4137, 2011 | 82 | 2011 |
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar–ductal metaplasia X Liu, JR Pitarresi, MC Cuitiño, RD Kladney, SA Woelke, GM Sizemore, ... Genes & Development 30 (17), 1943-1955, 2016 | 57 | 2016 |
Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation V Prabhu, P Srivastava, N Yadav, M Amadori, A Schneider, A Seshadri, ... Mitochondrion 13 (5), 493-499, 2013 | 52 | 2013 |
Pharmacologic Activation of the G Protein–Coupled Estrogen Receptor Inhibits Pancreatic Ductal Adenocarcinoma CA Natale, J Li, JR Pitarresi, RJ Norgard, T Dentchev, BC Capell, ... Cellular and molecular gastroenterology and hepatology 10 (4), 868-880. e1, 2020 | 47 | 2020 |
MYC levels regulate metastatic heterogeneity in pancreatic adenocarcinoma R Maddipati, RJ Norgard, T Baslan, KS Rathi, A Zhang, A Saeid, ... Cancer discovery 12 (2), 542-561, 2022 | 46 | 2022 |
Calcium signaling induces a partial EMT RJ Norgard, JR Pitarresi, R Maddipati, NM Aiello‐Couzo, D Balli, J Li, ... EMBO reports 22 (9), e51872, 2021 | 39 | 2021 |
PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability JR Pitarresi, RJ Norgard, AM Chiarella, K Suzuki, B Bakir, V Sahu, J Li, ... Cancer discovery 11 (7), 1774-1791, 2021 | 38 | 2021 |
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth JR Pitarresi, X Liu, A Avendano, KA Thies, GM Sizemore, AM Hammer, ... Life Science Alliance 1 (5), e201800190, 2018 | 35 | 2018 |
Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer TA Karakasheva, JT Gabre, UM Sachdeva, R Cruz-Acuña, EW Lin, ... Scientific Reports 11 (1), 21304, 2021 | 33 | 2021 |
Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia JR Pitarresi, X Liu, SM Sharma, MC Cuitiño, RD Kladney, TA Mace, ... Neoplasia 18 (9), 541-552, 2016 | 33 | 2016 |
Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis JA Wallace, JR Pitarresi, N Sharma, M Palettas, MC Cuitiño, ST Sizemore, ... Frontiers in oncology 4, 2014 | 30 | 2014 |
PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells B Marchand, JR Pitarresi, M Reichert, K Suzuki, D Laczkó, AK Rustgi Oncogene, 1, 2019 | 28 | 2019 |
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer JE Lefler, CB MarElia-Bennett, KA Thies, BE Hildreth, SM Sharma, ... Life Science Alliance 5 (11), 2022 | 26 | 2022 |
The LIN28B–IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine P Chatterji, KE Hamilton, S Liang, SF Andres, HRS Wijeratne, R Mizuno, ... Genes & development 32 (15-16), 1020-1034, 2018 | 21 | 2018 |