Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci FR Schumacher, AA Al Olama, SI Berndt, S Benlloch, M Ahmed, ... Nature genetics 50 (7), 928-936, 2018 | 876 | 2018 |
Prediction of breast cancer risk based on profiling with common genetic variants N Mavaddat, PDP Pharoah, K Michailidou, J Tyrer, MN Brook, MK Bolla, ... Journal of the National Cancer Institute 107 (5), djv036, 2015 | 705 | 2015 |
Genome-wide association studies identify four ER negative–specific breast cancer risk loci M Garcia-Closas, FJ Couch, S Lindstrom, K Michailidou, MK Schmidt, ... Nature genetics 45 (4), 392-398, 2013 | 487 | 2013 |
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021 | 389 | 2021 |
Association of body mass index and age with subsequent breast cancer risk in premenopausal women MJ Schoemaker, HB Nichols, LB Wright, MN Brook, ME Jones, ... JAMA oncology 4 (11), e181771-e181771, 2018 | 343 | 2018 |
Interim results from the IMPACT study: evidence for prostate-specific antigen screening in BRCA2 mutation carriers EC Page, EK Bancroft, MN Brook, M Assel, MH Al Battat, S Thomas, ... European urology 76 (6), 831-842, 2019 | 245 | 2019 |
Breast cancer risk after recent childbirth: a pooled analysis of 15 prospective studies HB Nichols, MJ Schoemaker, J Cai, J Xu, LB Wright, MN Brook, ME Jones, ... Annals of internal medicine 170 (1), 22-30, 2019 | 196 | 2019 |
Shared heritability and functional enrichment across six solid cancers X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, ... Nature communications 10 (1), 431, 2019 | 128 | 2019 |
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium A Rudolph, M Song, MN Brook, RL Milne, N Mavaddat, K Michailidou, ... International journal of epidemiology 47 (2), 526-536, 2018 | 114 | 2018 |
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants T Dadaev, EJ Saunders, PJ Newcombe, E Anokian, DA Leongamornlert, ... Nature communications 9 (1), 2256, 2018 | 109 | 2018 |
Comparative validation of breast cancer risk prediction models and projections for future risk stratification P Pal Choudhury, AN Wilcox, MN Brook, Y Zhang, T Ahearn, N Orr, ... JNCI: Journal of the National Cancer Institute 112 (3), 278-285, 2020 | 94 | 2020 |
iCARE: An R package to build, validate and apply absolute risk models P Pal Choudhury, P Maas, A Wilcox, W Wheeler, M Brook, D Check, ... PloS one 15 (2), e0228198, 2020 | 85 | 2020 |
Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective … P Pal Choudhury, MN Brook, AN Hurson, A Lee, CV Mulder, P Coulson, ... Breast Cancer Research 23, 1-5, 2021 | 78 | 2021 |
Genetic predisposition to ductal carcinoma in situ of the breast C Petridis, MN Brook, V Shah, K Kohut, P Gorman, M Caneppele, D Levi, ... Breast Cancer Research 18, 1-15, 2016 | 78 | 2016 |
Temporal stability and determinants of white blood cell DNA methylation in the breakthrough generations study JM Flanagan, MN Brook, N Orr, K Tomczyk, P Coulson, O Fletcher, ... Cancer Epidemiology, Biomarkers & Prevention 24 (1), 221-229, 2015 | 75 | 2015 |
A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study EK Bancroft, EC Page, MN Brook, S Thomas, N Taylor, J Pope, J McHugh, ... The Lancet Oncology 22 (11), 1618-1631, 2021 | 72 | 2021 |
Germline DNA repair gene mutations in young-onset prostate cancer cases in the UK: evidence for a more extensive genetic panel DA Leongamornlert, EJ Saunders, S Wakerell, I Whitmore, T Dadaev, ... European urology 76 (3), 329-337, 2019 | 70 | 2019 |
Genetic predisposition to in situ and invasive lobular carcinoma of the breast E Sawyer, R Roylance, C Petridis, MN Brook, S Nowinski, E Papouli, ... PLoS genetics 10 (4), e1004285, 2014 | 62 | 2014 |
Germline variation at 8q24 and prostate cancer risk in men of European ancestry M Matejcic, EJ Saunders, T Dadaev, MN Brook, K Wang, X Sheng, ... Nature communications 9 (1), 4616, 2018 | 60 | 2018 |
Mitochondrial DNA copy number in peripheral blood cells and risk of developing breast cancer A Lemnrau, MN Brook, O Fletcher, P Coulson, K Tomczyk, M Jones, ... Cancer research 75 (14), 2844-2850, 2015 | 57 | 2015 |